Bezafibrat
|
|
|
- CAS-Nr.
- 41859-67-0
- Bezeichnung:
- Bezafibrat
- Englisch Name:
- Bezafibrate
- Synonyma:
- CEDUR;bf-759;bm15075;Befizal;Bezatol;BEZALIP;Difaterol;Bezabrate;bezafibrat;bezafibrato
- CBNumber:
- CB1188501
- Summenformel:
- C19H20ClNO4
- Molgewicht:
- 361.82
- MOL-Datei:
- 41859-67-0.mol
|
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
|
|
| R-Sätze: |
22 |
|
|
| S-Sätze: |
36 |
|
|
| WGK Germany |
1 |
|
|
| RTECS-Nr. |
UE8755000 |
|
|
| HS Code |
29242990 |
|
|
| Toxizität |
LD50 oral in rat: 1082mg/kg |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
|
| Sicherheit |
|
Bezafibrat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Bezafibrate is a non-selective agonist of peroxisome proliferator-activated receptors (PPARs; EC
50s = 50, 60, and 20 μM for human PPARα, PPARγ, and PPARδ, respectively). It reduces triglyceride levels and the size of lipid droplets in an oleic acid-induced HepaRG hepatocyte model of steatosis when used at a concentration of 25 μM. Bezafibrate (10 mg/kg per day) reduces plasma VLDL and LDL mass and triglyceride and free fatty acid levels in a high-fructose plus lard diet-induced rat model of insulin resistance.
Chemische Eigenschaften
Off-White Solid
Verwenden
Bezafibrate has been used:
- a supplement in the standard diet (SD)?for mice to study its effect on diabetes
- to evaluate its effect on hepatitis C virus (HCV) assembly and secretion
- to evaluate its effect on gonadal steroidogenesis and?spermatogenesis?of zebrafish and also used as standard for HPLC
Bezafibrat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Bezafibrat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 384)Lieferanten
41859-67-0(Bezafibrat)Verwandte Suche:
- Bezafibrate D6 (dimethyl D6)
- Bezabrate D6 (DiMethyl D6)
- 2-(4-{2-[(4-chlorophenyl)forMaMido]ethyl}phenoxy)-2-Methylpropanoic acid
- Bezafibrate-d6
- BEZAFIBRATE EPB(CRM STANDARD)
- BEZAFIBRATE MM(CRM STANDARD)
- bezafibrat
- bezafibrato
- bf-759
- bm15075
- ([(Chloro-4-benzamido)-2-ethyl]-4-phenoxy)-2-methylpropionic acid
- 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxyl]-2-methylpropanoic Acid
- Befizal
- Bezatol
- Difaterol
- 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid
- 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropionic acid
- Bezafibrate,2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid
- 2-[4-[2-(4-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPANOIC ACID
- 2-[4-(2-[4-CHLOROBENZAMIDO]ETHYL)-PHENOXYL]-2-METHYLPROPANOIC ACID
- 2-[4-(2-[4-CHLOROBENZOMIDO]ETHYL)-PHENOXY]-2-METHYLPROPANOIC ACID
- 2-(4-(2-((4-CHLOROBENZOYL)AMINO)ETHYL)PHENOXY)-2-METHYLPROPIONIC ACID
- Propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-
- Bezafibrate, 98.0%(LC&T
- Bezafibrate Imp.(EP)
- AURORA KA-851
- BEZAFIBRATE
- BEZALIP
- CEDUR
- 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-propionicaci
- 2-(p-(2-(p-chlorobenzamido)ethyl)phenoxy)-2-methylpropionicacid
- Bezafibrate 41859-67-0
- BezafibrateQ: What is
Bezafibrate Q: What is the CAS Number of
Bezafibrate Q: What is the storage condition of
Bezafibrate Q: What are the applications of
Bezafibrate
- Bezafibrate CRS
- Bezafibrate >
- Bezabrate
- 2-[4-[2-[[(4-chlorophenyl)-oxomethyl]amino]ethyl]phenoxy]-2-methylpropanoate
- Bezafibrate Solution, 100ppm
- 2-(89-Chlorobenzoyl)benzoic&acid
- N-(4-Chlorobenzoyl)-Tyramine (Bezafibrate Intermediate)
- 41859-67-0
- 637927-29-7
- 1859-67-0
- C19H20ClNO4
- Cell Biology
- Cell Signaling and Neuroscience
- BioChemical
- Gene Regulation and Expression
- PPAR and RXR Regulators
- Intracellular receptor
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Active Pharmaceutical Ingredients
- Pharmaceutical intermediates
- Cardiovascular Drugs
