Pregabalin
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- CAS-Nr.
- 148553-50-8
- Englisch Name:
- Pregabalin
- Synonyma:
- Pregablin;Pregabilin;3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;Pregabali;PREDNISOLONESODIUMPHOSPHATE;PREGABAIN;Prebagalin;1-pregabalin;Pregabalin CRS;3-(Aminomethyl)-5-methyl-hexanoic acid
- CBNumber:
- CB2251105
- Summenformel:
- C8H17NO2
- Molgewicht:
- 159.23
- MOL-Datei:
- 148553-50-8.mol
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Pregabalin Eigenschaften
- Schmelzpunkt:
- 194-196°C
- alpha
- D23 +10.52° (c = 1.06 in water)
- Siedepunkt:
- 274.0±23.0 °C(Predicted)
- Dichte
- 0.997±0.06 g/cm3(Predicted)
- Flammpunkt:
- 9℃
- storage temp.
- 2-8°C
- Löslichkeit
- deionized water: ≥10mg/mL
- pka
- 4.23±0.10(Predicted)
- Aggregatzustand
- white powder
- Wasserlöslichkeit
- Soluble to 100 mM in water
- BCS Class
- 1
- InChI
- InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1
- InChIKey
- AYXYPKUFHZROOJ-ZETCQYMHSA-N
- SMILES
- C(O)(=O)C[C@@H](CN)CC(C)C
- CAS Datenbank
- 148553-50-8(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
 
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H336 |
Kann Schläfrigkeit und Benommenheit verursachen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Schläfrigkeit und Benommenheit) |
Warnung |
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P261, P271, P304+P340, P312,P403+P233, P405, P501 |
| H361 |
Kann vermutlich die Fruchtbarkeit beeinträchtigen oder das Kind im Mutterleib schädigen. |
Reproduktionstoxizität |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P261 |
Einatmen von Staub vermeiden. |
| P271 |
Nur im Freien oder in gut belüfteten Räumen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P308+P313 |
BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
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Pregabalin Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Pregabalin (Lyrica), a derivative of GABA that is closely related to gabapentin, has undergone extensive research for its efficacy in treating conditions such as generalized anxiety disorder (GAD), fibromyalgia, neuropathic pain, and partial complex seizures. It seems to have a more targeted effect on the a2-δ subunit of calcium channels in the brain compared to gabapentin. Pregabalin was granted FDA approval at the end of 2004 for the treatment of neuropathic pain and epilepsy. In 2008, it became the first medication approved for the management of fibromyalgia. Although pregabalin was approved for GAD treatment in the European Union in 2006, it has not yet received FDA approval for GAD in the United States as of the time of writing.
Chemische Eigenschaften
Off-White Solid
Verwenden
S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.
Allgemeine Beschreibung
Pregabalin, marketed as the anticonvulsant drug Lyrica, is used in the treatment of epilepsy and generalized anxiety disorder. Along with other anticonvulsants such as gabapentin and levetiracetam, pregabalin is also used to treat neuropathic pain. This certified reference standard is suitable for pregabalin GC/MS or LC/MS applications from forensic analysis, clinical toxicology and pain prescription monitoring to urine drug testing.
Pregabalin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Pregabalin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 881)Lieferanten
148553-50-8()Verwandte Suche:
- PREGABALIN
- (R)-Pregabalin
- (S)-Pregabalin
- (S)-3-(Ammoniomethyl)-5-methylhexanoate
- 3(S)-(AMINOMETHYL)-5
- Pregabalin-13C3 RaceMic
- PREGABALINE (S)-(+)-3-AMinoMethyl-5-Methylhexanoic acid
- (S)-(+)-Pregabalin-d4
- xiangxizhiliao
- Pregabalin (S)-(+)-3-AMinoMethyl-5-Methylhexanoic acid
- (S)-Pregabalin (1.0 Mg/ML in Methanol)
- Pregabalin SynonyMs 3-(AMinoMethyl)-5-Methyl-hexanoic acid
- Pregabalin
3-(Aminomethyl)-5-methyl-hexanoic acid
- Pregabalin solution
- Hexanoic acid, 3-(aminomethyl)-5-methyl-, (3S)-
- Pregabalin and Intermediates
- Pregabalin kf-wang(at)kf-chem.com
- API Pregabalin 148553-50-8 wickr alinalee
- (S)-3-(Aminomethyl)-5-methylhexanoic acid (Pregabalin)
- Neugaba 75
- Maxgalin 75
- Pregabalin Manufacturer
- ACTIVE PHARMACEUTICALS INGRADIENTS : PRE GABALIN 3-( AMINOMETHYL)-5-METHYL-HEXANO IC ACID (OTHER) [TAX I
- Pregabalin powder 99%
- APIPregabalin
- Pregabalin powder
- 3-(aminomethyl)-5-methyl-(3S)-Hexanoic acid
- TOS-BB-0910
- Pregabalin Lyric Pregablin
- Prebagalin for sale
- Pregabalin Basic information
- Pregabalin USP/EP/BP
- pure pregabalin
- (S)(+)-3-Aminomethyl-5-methyl-hecanoic acid
- crystal Pregabalin
- Pregabalin -IP/IH/USP/EP
- prégabaline
- Pregabalin #69-1 gram
- Pregabalin (Y0001805)Q: What is
Pregabalin (Y0001805) Q: What is the CAS Number of
Pregabalin (Y0001805)
- Pregabalin D6
- PregabalinQ: What is
Pregabalin Q: What is the CAS Number of
Pregabalin Q: What is the storage condition of
Pregabalin Q: What are the applications of
Pregabalin
- Pregabalin CV (1559618)
- pregabalin crystal
- 3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID
- (3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID
- Pregablin
- 3-(Aminomethyl)-5-methyl-hexanoic acid
- PREDNISOLONESODIUMPHOSPHATE
- Pregabilin
- Pregabalin CRS
- Prebagalin
- Pregabali
- PREGABAIN
- 1-pregabalin
- Pregabalin C8H17NO2
- Pregabalin (CRM)
- Pregabalin
IP/BP/EP/USP
- Prybalin
