N,N-Diethyl-α-methyl-10H-phenothiazin-10-ethylaminmonohydrochlorid
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- CAS-Nr.
- 1094-08-2
- Bezeichnung:
- N,N-Diethyl-α-methyl-10H-phenothiazin-10-ethylaminmonohydrochlorid
- Englisch Name:
- Ethopropazine Hydrochloride
- Synonyma:
- parfezin;NSC 64074;NSC 169467;PROFENAMIN HCL;ProphenamineHCl;Profenamine HCl;ethopropazine hcl;Ethopropazine hydroc;lysivanehydrochloride;parsidolhydrochloride
- CBNumber:
- CB3149595
- Summenformel:
- C19H25ClN2S
- Molgewicht:
- 348.93
- MOL-Datei:
- 1094-08-2.mol
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N,N-Diethyl-α-methyl-10H-phenothiazin-10-ethylaminmonohydrochlorid Eigenschaften
- Schmelzpunkt:
- 223-225° (some decompn)
- storage temp.
- 2-8°C
- Löslichkeit
- DMSO: >5mg/mL at ~60°C, clear
- Aggregatzustand
- powder
- Farbe
- white
- Merck
- 13,3783
- Stabilität:
- Hygroscopic
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
22 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
SO5002000 |
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| Toxizität |
LD50 s.c. in mice: 670 mg/kg (Farquharson, Johnston) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P330 |
Mund ausspülen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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N,N-Diethyl-α-methyl-10H-phenothiazin-10-ethylaminmonohydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
Verwenden
Ethopropazine hydrochloride is a drug that shifts energy metabolism from mitochondrial respiration to glycolysis.
Definition
ChEBI: The monohydrochloride salt of profenamine. An antimuscarinic, it is used for the symptomatic treatment of Parkinson's disease.
Allgemeine Beschreibung
Ethopropazinehydrochloride, 10-[2-(diethylamino)propyl]phenothiazinemonohydrochloride (Parsidol), introduced to therapy in1954, has antimuscarinic activity and is especially useful inthe symptomatic treatment of parkinsonism. In this capacity,it has value in controlling rigidity, and it also has a favorableeffect on tremor, sialorrhea, and oculogyric crises.
Clinical Use
Ethopropazine Hydrochloride is oftenused in conjunction with other antiparkinsonian drugs forcomplementary activity.Side effects are common with this drug but are usuallynot severe. Drowsiness and dizziness are the most commonside effects at ordinary dosage levels, and as the dose increases,xerostomia, mydriasis, and others become evident.It is contraindicated in conditions such as glaucoma becauseof its mydriatic effect.
N,N-Diethyl-α-methyl-10H-phenothiazin-10-ethylaminmonohydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N,N-Diethyl-α-methyl-10H-phenothiazin-10-ethylaminmonohydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 50)Lieferanten
1094-08-2(N,N-Diethyl-α-methyl-10H-phenothiazin-10-ethylaminmonohydrochlorid)Verwandte Suche:
- lysivanehydrochloride
- n,n-diethyl-alpha-methyl-10h-phenothiazine-10-ethanaminmonohydrochloride
- n,n-diethyl-alpha-methyl-10-phenothiazineethylaminhydrochloride
- profenaminemonohydrochloride
- ethopropazine hcl
- 10H-Phenothiazine-10-ethanamine, N,N-diethyl-.alpha.-methyl-, monohydrochloride
- 10H-Phenothiazine-10-ethanamine, N,N-diethyl-a-methyl-, monohydrochloride (9CI)
- NSC 169467
- NSC 64074
- Phenothiazine, 10-[2-(diethylamino)propyl]-, hydrochloride (7CI)
- Phenothiazine, 10-[2-(diethylamino)propyl]-, monohydrochloride (8CI)
- 10-(2-Diethylaminopropyl)phenothiazine, 10-[2-(Diethylamino)propyl]phenothiazine hydrochloride, Dibutil hydrochloride, Parkin
- N,N-diethyl-alpha-methyl-10H-phenothiazine-10-ethylamine monohydrochloride
- ProphenamineHCl
- 10-[2-(Diethylamino)propyl]phenothiazine hydrochloride
- N-(2-diethylaMinopropyl)-phenothiazine hydrochloride
- N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride
- parfezin
- parsidolhydrochloride
- parsidolmonohydrochloride
- profenaminehydrochloride
- 10-[2-DIETHYLAMINOPROPYL]PHENOTHIAZINE
- LABOTEST-BB LT00452011
- ETHOPROPAZINE HYDROCHLORIDE
- SALOR-INT L308765-1EA
- 10-(2-(diethylamino)propyl)-phenothiazinmonohydrochloride
- isothazinehydrochloride
- l-10-(2-diethylaminopropyl)phenothiazinehydrochloride
- Profenamine HCl
- Ethopropazine hydroc
- PROFENAMIN HCL
- Ethopropazine hydrochloride >=98% (HPLC), powder
- 1094-08-2
- C19H24N2SHCl
- C19H25ClN2S
