1-Boc-4-(4-fluoro-phenylamino)-piperidine

1-Boc-4-(4-fluoro-phenylamino)-piperidine Struktur
288573-56-8
CAS-Nr.
288573-56-8
Englisch Name:
1-Boc-4-(4-fluoro-phenylamino)-piperidine
Synonyma:
tert-butyl 4-(4-fluoroanilino)piperidine-1-carboxylate;KS0037;Pharmaceutical Powder;tert-Butyl 4-(4-fluoroanilino)-1-;1-Piperidinecarboxylicacid CAS 288573-56-8;High purity 4-[(4-fluorophenyl)amino]- CAS 288573-56-8;KS-0037 powder;1,1-dimethylethyl ester CAS 288573-56-8;1-Boc-4- (4-fluorophenamide) -piperidine;Boc-4- (4-FLUORO-PHENYLAMINO) -Piperidine
CBNumber:
CB3280285
Summenformel:
C16H23FN2O2
Molgewicht:
294.36
MOL-Datei:
288573-56-8.mol

1-Boc-4-(4-fluoro-phenylamino)-piperidine Eigenschaften

Siedepunkt:
400.4±40.0 °C(Predicted)
Dichte
1.159±0.06 g/cm3(Predicted)
pka
5.09±0.20(Predicted)
InChI
InChI=1S/C16H23FN2O2/c1-16(2,3)21-15(20)19-10-8-14(9-11-19)18-13-6-4-12(17)5-7-13/h4-7,14,18H,8-11H2,1-3H3
InChIKey
TUYSUNKDSSHKHM-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(NC2=CC=C(F)C=C2)CC1

Sicherheit

1-Boc-4-(4-fluoro-phenylamino)-piperidine Chemische Eigenschaften,Einsatz,Produktion Methoden

synthetische

Sodium cyanoborohydride (661 mg, 10.0 mmol) was added to a methylene chloride solution (30 ml) of t-butyl 4-oxopiperidine-1-carboxylate (2.66 g, 13.1 mmol), 4-fluoroaniline (1.46 g, 13.1 mmol) and acetic acid (0.750 ml, 13.1 mmol), at 0°C, and stirring was carried out at room temperature for 15 hours. A saturated aqueous sodium hydrogencarbonate solution was added to the reaction solution, followed by extraction with ethyl acetate, and the extract was washed sequentially with water and saline, and dried over anhydrous sodium sulfate. The organic layer was concentrated and the resulting residue was washed with diisopropyl ether, followed by drying to afford 1-Boc-4-(4-Fluoro-Phenylamino)-Piperidine. Yield 80%.
1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE

1-Boc-4-(4-fluoro-phenylamino)-piperidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


  • 1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE
  • 1-tert-Butoxycarbonyl-4-[(4-fluorophenyl)amino]piperidine
  • 1,1-dimethylethyl ester CAS 288573-56-8
  • 1-Piperidinecarboxylic acid, 4-[(4-fluorophenyl)amino]-, 1,1-dimethylethyl ester
  • 1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE Basic information
  • China Tert-Butyl 4- (4-fluoroanilino) Piperidine-1-Carboxylate
  • KS-0037 powder
  • 4-[(4-Fluorophenyl)Amino]Piperidine-1-Carboxylate
  • Boc-4- (4-FLUORO-PHENYLAMINO) -Piperidine
  • 1-Boc-4-(4-Fluoro-phenylamino)-piperidine KS-0037
  • 1-Piperidinecarboxylicacid, 4-[(4-fluorophenyl)amino]-, 1,1-...
  • tert-butyl 4-(4-fluoroanilino)piperidine-1-carboxylate
  • High purity 4-[(4-fluorophenyl)amino]- CAS 288573-56-8
  • 1-Piperidinecarboxylicacid CAS 288573-56-8
  • KS0037
  • Pharmaceutical Powder
  • tert-Butyl 4-(4-fluoroanilino)-1-
  • 1-Boc-4-(4-fluoro-phenylamino)-piperidine,tert-butyl 4-(4-fluoroanilino)piperidine-1-carboxylate
  • 1-Boc-4- (4-fluorophenamide) -piperidine
  • ert-butyl4-(4-fluoroanilino)piperidine-1-carboxylate
  • ks-0037, 1-BOC-4-(4-fluorophenylamine)-piperidine
  • 288573-56-8
  • 2573-56-8
  • 288573-56-8
  • 1
  • Pharm
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