Medroxyprogesteron

MEDROXYPROGESTERONE Struktur
520-85-4
CAS-Nr.
520-85-4
Bezeichnung:
Medroxyprogesteron
Englisch Name:
MEDROXYPROGESTERONE
Synonyma:
(-)-Allantoin;u8840;farlutal;NSC 27408;Medoxyprogesterone;medroxyprogesteron;6-DIHYDROMEGESTROL;MEDROXYPROGESTERONE;METHYLOXYPROGESTERONE;Medroxyprogesteronebase
CBNumber:
CB3419654
Summenformel:
C22H32O3
Molgewicht:
344.49
MOL-Datei:
520-85-4.mol

Medroxyprogesteron Eigenschaften

Schmelzpunkt:
204-206°C
alpha 
D25 +75° (in chloroform)
Siedepunkt:
419.57°C (rough estimate)
Dichte
1.0906 (rough estimate)
Brechungsindex
1.5000 (estimate)
storage temp. 
Sealed in dry,Room Temperature
Löslichkeit
Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
13.03±0.70(Predicted)
Farbe
White
Merck 
13,5817
BRN 
2510965
CAS Datenbank
520-85-4(CAS DataBase Reference)
EPA chemische Informationen
Medroxyprogesterone (520-85-4)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn
R-Sätze: 48-63-68
S-Sätze: 22-24/25
WGK Germany  3
RTECS-Nr. TU5300000
HS Code  29372390
Giftige Stoffe Daten 520-85-4(Hazardous Substances Data)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H361 Kann vermutlich die Fruchtbarkeit beeinträchtigen oder das Kind im Mutterleib schädigen. Reproduktionstoxizität Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

Medroxyprogesteron Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R48:Gefahr ernster Gesundheitsschäden bei längerer Exposition.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
R68:Irreversibler Schaden möglich.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

MEDROXYPROGESTERONE is White Solid

Verwenden

MEDROXYPROGESTERONE is an orally active progestogen used in hormone replacement therepy (HRT), in the past has been used as a component of oral contraceptives.

Definition

ChEBI: A 3-oxo Delta4-steroid that is pregn-4-ene-3,20-dione substituted by an alpha-hydroxy group at position 17 and a methyl group at position 6.

läuterung methode

If it contains the epi-isomer (TLC), then dissolve it in CHCl3, bubble dry HCl gas to epimerise it, evaporate and recrystallise it from chloroform. The UV has max at 241nm ( 16,150) in EtOH. The 17-acetate [71-58-9] crystallises from MeOH with m 207-208o and [] D 25 +61o (CHCl3). Its UV has max at 240nm ( 15,950) in EtOH. [Babcock et al. J Am Chem Soc 80 2904 1958, Beilstein 8 IV 2212.]

Medroxyprogesteron Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Medroxyprogesteron Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 164)Lieferanten
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520-85-4(Medroxyprogesteron)Verwandte Suche:


  • PREGN-4-ENE-3,20-DIONE,17-HYDROXY-6-ALPHA-METHYL-
  • 17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione, 17α-Hydroxy-6α-methylprogesterone, 6α-Methyl-5-pregnen-17α-ol-3,20-dione, 6-Dihydromegestrol
  • (6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
  • (6S,8R,9S,10R,13S,14S,17R)-17-ethanoyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
  • 4-Pregnen-6a-Methyl-17-ol-3,20-dione-d7
  • (6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-triMethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
  • Medroxyprogesterone acetate-13C2-d3
  • 6alpha-Methyl-17alpha-hydroxypregn-4-ene-3,20-dione
  • Medoxyprogesterone
  • medroxyprogesterone solution,100ppm
  • Medroxyprogesterone acetate Related Compound B
  • farlutal
  • medroxyprogesteron
  • u8840
  • 6α-methyl-17α-hydroxyprogesterone
  • MEDROXYPROGESTERONE VETRANAL, 100 MG
  • 6A-METHYL-17A-HYDROXYPROGESTERONE
  • MEDROXYPROGESTERONE MM(CRM STANDARD)
  • Medroxyprogesteronebase
  • 17-Hydroxy-6α-methylpregn-4-ene-3,20-dione
  • 17α-hydroxy-6α-methyl-4-pregnene-3,20-dione
  • (6S,8R,9R,10S,13S,14R,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
  • 17a-Hydroxy-6a-methylprogesterone
  • 17-Hydroxy-6a-methyl-pregn-4-ene-3,20-dione
  • 17-Hydroxy-6a-methylpregn-4-ene-3,20dione
  • 17-Hydroxy-6a-methylprogesterone
  • 6a-Methyl-17a-hydroxypregn-4-ene-3,20-dione
  • 6a-Methyl-17-hydroxyprogesterone
  • 6a-Methyl-4-pregnen-17-a-ol-3,20-dione
  • 6a-Methyl-4-pregnen-17a-ol-3,20-dione
  • NSC 27408
  • Pregn-4-ene-3,20-dione, 17-hydroxy-6a-methyl- (7CI, 8CI)
  • Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6a)- (9CI)
  • MEDROXYPROGESTERONE
  • METHYLOXYPROGESTERONE
  • HYDROXYMETHYLPROGESTERONE
  • 17ALPHA-HYDROXY-6ALPHA-METHYL-4-PREGNENE-3,20-DIONE
  • 17-hydroxy-6-methyl-20-dion(6alpha)-pren-4-ene-
  • 6alpha-methyl-4-pregnen-17alpha-ol-3,20-dione
  • 17ALPHA-HYDROXY-6ALPHA-METHYLPROGESTERONE
  • 6-DIHYDROMEGESTROL
  • 6ALPHA-METHYL-17ALPHA-HYDROXY-PROGESTERONE
  • 6-ALPHA-METHYL-17-HYDROPROGESTERONE
  • 6ALPHA-METHYL-5-PREGNEN-17ALPHA-OL-3,20-DIONE
  • 4-PREGNEN-6-ALPHA-METHYL-17-OL-3,20-DIONE
  • 17-hydroxy-6-alpha-methyl-pregn-4-ene-20-dione
  • 17-hydroxy-6alpha-methyl-pregn-4-ene-20-dione
  • 17-hydroxy-6alpha-methyl-pregn-4-ene-3,20-dione
  • 17-hydroxy-6alpha-methylprogesterone
  • 17-hydroxy-6-methyl-20-dion(6-alpha)-pregn-4-ene-
  • Medroxyprogesterone Acetate EP impurity B
  • Pregn-4-ene-3,20-dione,17-hydroxy-6-methyl-, (6a)-
  • Medroxyprogesterone (Medroxyprogesterone Acetate EP Impurity B)
  • Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6α)-
  • Medroxyprogesterone Solution in Acetonitrile, 100μg/mL
  • Medroxyprogesterone Acetate Impurity 2 (Medroxyprogesterone Acetate EP Impurity B)
  • MedroxyprogesteroneQ: What is Medroxyprogesterone Q: What is the CAS Number of Medroxyprogesterone Q: What is the storage condition of Medroxyprogesterone Q: What are the applications of Medroxyprogesterone
  • Medroxyprogesterone Acetate Related Compound B (17-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione) (1378023)
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