URSODEOXYCHOLIC-2,2,4,4-D4 ACID

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ursodeoxycholic acid-d₄ (UDCA-d₄) is intended for use as an internal standard for the quantification of UDCA (Item No. 15121) by GC- or LC-MS. UDCA is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; ). UDCA is also a metabolite of lithocholic acid (LCA; ) in human liver microsomes. It inhibits taurocholic acid uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC₅₀ value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.

Verwenden

Ursodeoxycholic Acid-d4 is a deuterated form of Ursodeoxcholic Acid (U850000), which is used as an anticholelithogenic. Ursodeoxcholic Acid is an epimer with Chenodiol with respect to the hydroxyl group at C7. Ursodeoxycholic Acid-d4 was used as an internal standard for rapid quantification of bile acids by liquid chromatography-tandem mass spectrometry.

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32024	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-4000505016 13380397412	3001272453@qq.com	China	5050	50
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9679	58
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	18044	56
Artis Biotech Co. Ltd.	0575-18780151478 18582380095	sales@artisbio.com	China	2965	58
Chengdu Novel Biomedical Co., Ltd.	028-85255396 18302801538	cdnovell@163.com	China	2304	58
Nanjing Haolv Biotechnology Co.,Ltd	025-84622273 17361806303	3004208264@qq.com	China	3021	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11217	58

347841-46-7()Verwandte Suche:

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• URSODEOXYCHOLIC-2,2,4,4-D4 ACID
• Ursodeoxycholic-d4 Acid
• (4R)-4-[(3R,5R,7S,8R,9S,10S,13R,14S,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• (4R)-4-[(3R,5R,7S,8R,9S,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• Ursodiol-d4 (Ursodeoxycholic Acid-d4)
• Ursodeoxycholic acid-[d4] (Solution)
• URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 95% CHEMICAL PURITY
• URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
• Ursodeoxycholic Acid-d4 MaxSpec? Standard
• Ursodeoxycholic Acid-2,2,4,4-d4 (Major)
• (4R)-4-[(3R,5S,7S,8R,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• 2H4]-Ursodeoxycholic Acid
• Urosodeoxycholic Acid Impurity 28
• *Dronedarone Impurity 37 ( Tributylamine)
• URSODEOXYCHOLICACID(2,2,4,4-D4) IN METHANOL
• 347841-46-7
• C24H36D4O4
• Bile Acids - 13C & 2H