4-Acetoxyindole
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- CAS-Nr.
- 5585-96-6
- Englisch Name:
- 4-Acetoxyindole
- Synonyma:
- 1H-indol-4-yl acetate;2-(1H-indol-4-yl)acetate;Acetic acid 1H-indol-4-yl ester;ACETOXYINDOLE;4-ACETOXYINDOLE;4-acacetoxyindole;4-INDOLYL ACETATE;4-INDOXYL ACETATE;4-Acetoxy-1H-indole;4-Acetoxyindole 98%
- CBNumber:
- CB4477655
- Summenformel:
- C10H9NO2
- Molgewicht:
- 175.18
- MOL-Datei:
- 5585-96-6.mol
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4-Acetoxyindole Eigenschaften
- Schmelzpunkt:
- 100-102°C
- Siedepunkt:
- 339.1±15.0 °C(Predicted)
- Dichte
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Löslichkeit
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 16.38±0.30(Predicted)
- Farbe
- Off-White to Beige
- InChI
- InChI=1S/C10H9NO2/c1-7(12)13-10-4-2-3-9-8(10)5-6-11-9/h2-6,11H,1H3
- InChIKey
- ZXDMUHFTJWEDEF-UHFFFAOYSA-N
- SMILES
- N1C2=C(C(OC(=O)C)=CC=C2)C=C1
- CAS Datenbank
- 5585-96-6(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xi |
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| WGK Germany |
3 |
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| Hazard Note |
Irritant |
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| HS Code |
2933998090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H332 |
Gesundheitsschädlich bei Einatmen. |
Akute Toxizität inhalativ |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P271, P304+P340, P312 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
| P310 |
Sofort GIFTINFORMATIONSZENTRUM/Arzt/ anrufen. |
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4-Acetoxyindole Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
4-acetoxylindole is also known as 4-Indolyl acetate. It can be used as standards of the reverse phase HPLC during separation of small molecules. It can also be used as reactant during the preparation of inhibitors of HIV-attachment, prostanoid EP3 antagonist, indolyl-nitroalkanes and psilocybin.
Verwenden
Reactant for preparation of:• ;Inhibitors of HIV-1 attachment1• ;Prostanoid EP3 receptor antagonist, as a novel antiplatelet agent2• ;Indolyl-nitroalkanes via N-bromosuccinimide catalyzed synthesis3• ;Psilocybin as a medicinal agent4
Allgemeine Beschreibung
4-Acetoxyindole is a chromophore that belongs to the pyrrole family of compounds. It has been shown to react with an ionic liquid under acidic conditions to form a protonated intermediate, which can be deprotonated by a nucleophile. This reaction yields an acetate anion and a fluorescing product. 4-Acetoxyindole also reacts with deuterium gas, yielding an acetate, a deuterium atom, and fluorescing product. The reaction is reversible and the yield of the product depends on the concentration of the reactants. 4-Acetoxyindole has strong carbonyl groups that make it reactive towards other functional groups. These reactions are useful for synthesizing heterocycles such as indoles and isoquinolines.
Einzelnachweise
http://www.sigmaaldrich.com/catalog/product/aldrich/259047?lang=en®ion=US
https://pubchem.ncbi.nlm.nih.gov/compound/4-Acetoxyindole
4-Acetoxyindole Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Acetoxyindole Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 239)Lieferanten
5585-96-6()Verwandte Suche:
- 4-ACETOXYINDOLE
- 4-INDOXYL ACETATE
- 4-INDOLYL ACETATE
- 4-INDOLYL ACETATE 99%
- ACETOXYINDOLE
- 4-Acetoxy-1H-indole
- 1H-Indol-4-ol,4-acetate
- 4-Acetoxyindole 98%
- 4-Индолил ацетат, 4-Indoxyl acetate, 1H-indol-4-yl acetate, 4-Acetoxyindole
- 4-Acetoxyindole in stock Factory
- 4-acacetoxyindole
- 5585-96-6 4-Acetoxyindole C10H9NO2
- 1H-indol-4-yl acetate
- 2-(1H-indol-4-yl)acetate
- Acetic acid 1H-indol-4-yl ester
- 5585-96-6
- Heterocyclic Building Blocks
- Indoles
- Building Blocks
- IndolesOxindoles
- Indoles and derivatives
- Building Blocks
- C10
- Chemical Synthesis
- Heterocyclic Building Blocks
- Indoles
- Indoline & Oxindole
- blocks
- 5585-96-6
