2-Amino-6-hydroxy-1H-pyrimidin-4-on
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- CAS-Nr.
- 56-09-7
- Bezeichnung:
- 2-Amino-6-hydroxy-1H-pyrimidin-4-on
- Englisch Name:
- 2-Amino-4,6-dihydroxypyrimidine
- Synonyma:
- 2-AMINOPYRIMIDINE-4,6-DIOL;2-amino-6-hydroxy-1h-pyrimidin-4-one;4(3H)-Pyrimidinone, 2-amino-6-hydroxy-;2-ADHP;NSC 15920;NSC 18692;AKOS 92830;AKOS BBS-00007961;TIMTEC-BB SBB004247;6-dihydroxypyriMidine
- CBNumber:
- CB6342676
- Summenformel:
- C4H5N3O2
- Molgewicht:
- 127.1
- MOL-Datei:
- 56-09-7.mol
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2-Amino-6-hydroxy-1H-pyrimidin-4-on Eigenschaften
- Schmelzpunkt:
- >300 °C (lit.)
- Siedepunkt:
- 235.85°C (rough estimate)
- Dichte
- 1.4748 (rough estimate)
- Brechungsindex
- 1.5000 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- Löslichkeit
- Soluble in Aqueous Alkali.
- pka
- 7.45±0.10(Predicted)
- Aggregatzustand
- Powder
- Farbe
- Off-white to light pink or light yellow
- BRN
- 510297
- InChIKey
- AUFJTVGCSJNQIF-UHFFFAOYSA-N
- CAS Datenbank
- 56-09-7(CAS DataBase Reference)
- EPA chemische Informationen
- 2-Amino-6-hydroxy-4(1H)-pyrimidinone (56-09-7)
2-Amino-6-hydroxy-1H-pyrimidin-4-on Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
2-Amino-4,6-dihydroxypyrimidine is a hydroxypyrimidine.
Chemische Eigenschaften
White Solid
Verwenden
2-Amino-4,6-dihydroxypyrimidine acts as an intermediate in the production of antimicrobial guanylsulfonamides. It also acts as an intermediate in pharmaceuticals and agrochemicals.
Synthese
The synthesis of 2-Amino-4,6-dihydroxypyrimidine is as follows:
A freshly-prepared sodiummethoxide solution in methanol (25 ml) was added to a round-bottomed flask containing guanidine hydrochloride(15 mmol), stirred for a few minutes, before dimethyl malonate (15 mmol)was slowly added. The mixture was heated under reflux for about 2-3hours. After evaporation of the solvent under reduced pressure, the resultingwhite solid was dissolved in a minimum amount of water and the pH adjusted to 6with 10% HCl. The precipitate obtained was filtered and washed with distilledwater and ethanol, respectively, to obtain pure 2-amino-4,6-pyrimidinediol.(Note: sodium methoxide solution was prepared by addition of small pieces ofsodium metal in methanol).Yield: 85%;solid, m.p. 195-197 °C.
2-Amino-6-hydroxy-1H-pyrimidin-4-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Amino-6-hydroxy-1H-pyrimidin-4-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 376)Lieferanten
56-09-7(2-Amino-6-hydroxy-1H-pyrimidin-4-on)Verwandte Suche:
- 2 - aMino - 4, 6-2 hydroxy pyriMidine
- 4(1H)-PYRIMIDINONE, 2-AMINO-6-HYDROXY-
- AKOS BBS-00007961
- AKOS 92830
- LABOTEST-BB LT00080685
- 4(1H)-Pyrimidinone, 2-amino-6-hydroxy- (8CI,9CI)
- 2-Amino-6-hydroxy-1H-pyrimidin-4-on
- 2-Amino-6-hydroxy-3H-pyrimidin-4-one
- 2-Amino-4,6-dihydroxypyrimidine,98%
- 2-Amino-3,4-dihydro-6-hydroxypyrimidine-4-one
- 2-Amino-6-hydroxypyrimidin-4(1H)-one
- 4,6-Dihydroxy-2-aminopyrimidine
- 6-dihydroxypyriMidine
- 2-AMino-4,6-dihydroxypyriMidine, 98% 100GR
- 2-AMino-4,6-dihydroxypyriMidine, 98% 25GR
- 2-amino-6-hydroxy-4(1h)-pyrimidinon
- 2-amino-6-hydroxy-4(1H)-Pyrimidinone
- 2-AMino-4,6-dioxypyriMidine
- 2-AMino-6-hydroxy-4(3H)-pyriMidinone
- NSC 15920
- NSC 18692
- 2-aMino-6-hydroxypyriMidin-4(3H)-one
- 2-AMino-4,6-dihydroxypyriMidine, 97+%
- 2-Amino-6-hydroxypyrimidin-4(3H)
- TIMTEC-BB SBB004247
- 2-AMINO-4,6-PYRIMIDINEDIOL
- 2-AMINO-4,6-DIHYDROXYPYRIMIDINE
- 2-ADHP
- 2-Amino-4,6-dihydroxypyrimidine >
- 2-Amino-4,6-dihydmidine
- 2-Amino-4,6-dihydroxypyrimidine ISO 9001：2015 REACH
- 2-amino-4-hydroxy-1H-pyrimidin-6-one
- 4(3H)-Pyrimidinone, 2-amino-6-hydroxy-
- 2-amino-6-hydroxy-1h-pyrimidin-4-one
- 2-AMINOPYRIMIDINE-4,6-DIOL
- 56-09-7
- 1956-0'9-7
- 1956-09-07
- 1956-09-7
- 1965-09-7
- 20-70-5
- C4H5N3O2
- Building Blocks
- Heterocyclic Building Blocks
- Pyrimidines
- Amines
- Aromatics
- Heterocycles
- 5-FOA
- Bases & Related Reagents
- Nucleotides
- Nucleotides and Nucleosides
- Pyrimidines
- PYRIMIDINE
- Pyridines, Pyrimidines, Purines and Pteredines
- Heterocycle-Pyrimidine series
