Levonorgestrel

Levonorgestrel Struktur
797-63-7
CAS-Nr.
797-63-7
Bezeichnung:
Levonorgestrel
Englisch Name:
Levonorgestrel
Synonyma:
L-NORGESTREL;levonova;Levonorgestrel for system suitability 1 CRS;wy-5104;postinor;Microlut;Microval;norplant2;Levonelle;Norgeston
CBNumber:
CB7125746
Summenformel:
C21H28O2
Molgewicht:
312.45
MOL-Datei:
797-63-7.mol

Levonorgestrel Eigenschaften

Schmelzpunkt:
206°C
alpha 
D20 -32.4° (c = 0.496 in CHCl3)
Siedepunkt:
392.36°C (rough estimate)
Dichte
1.0697 (rough estimate)
Brechungsindex
1.4900 (estimate)
storage temp. 
Sealed in dry,2-8°C
Löslichkeit
Practically insoluble in water, sparingly soluble in methylene chloride, slightly soluble in ethanol (96 per cent).
Aggregatzustand
Solid
pka
13.09±0.40(Predicted)
Farbe
Crystals from MeOH/CHCl3
Wasserlöslichkeit
10mg/L(temperature not stated)
Merck 
13,6736
BCS Class
1
InChI
InChI=1/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/s3
InChIKey
WWYNJERNGUHSAO-HABXDNTMNA-N
SMILES
C([C@]12CC[C@]3([H])[C@@]4([H])CCC(=O)C=C4CC[C@@]3([H])[C@]1([H])CC[C@@]2(O)C#C)C |&1:1,4,6,16,18,22,r|
CAS Datenbank
797-63-7(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn,T
R-Sätze: 20/21/22-40-60
S-Sätze: 22-36
WGK Germany  3
RTECS-Nr. JF8225000
HS Code  2937230000
Giftige Stoffe Daten 797-63-7(Hazardous Substances Data)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H351 Kann vermutlich Krebs verursachen. Karzinogenität Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
H362 Kann Säuglinge über die Muttermilch schädigen. Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
Sicherheit
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P260 Dampf/Aerosol/Nebel nicht einatmen.
P263 Kontakt während der Schwangerschaft /und der Stillzeit vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P308+P313 BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

Levonorgestrel Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R40:Verdacht auf krebserzeugende Wirkung.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

Levonorgestrel exhibits some androgenic activity but no glucocortic oid or antimineraloc orticoid action. Levonorgestrel can be administered orally, transdermally (combined with estradiol and formulated as a 7-day patch), and for prolonged, continuous use, via an intrauterine device (IUD). The oral bioavailability of levonorgestrel is approximately 95%. From a protein binding pers pective, 48% of an oral dose is bound to SHBG, and 50% is bound to albumin. Levonorgestrel under goes metabolic reduction of its ketone and is hydroxylated.

Chemische Eigenschaften

White Solid

Definition

A synthetic steroid hormone used as an ingredient of oral contraceptives. Approved by FDA.

Sicherheitsprofil

Human reproductive effects byingestion: menstrual cycle changes, fertility index.Questionable carcinogen with experimental neoplastigenicdata. When heated to decomposition it emits acrid smokeand irritating fumes.

Levonorgestrel Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Levonorgestrel Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 378)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Fortuna Chemical Co.,Ltd
+8618007136271
hk@fortunachem.com China 5998 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12829 58
Wuhan Haorong Biotechnology Co.,ltd
+86-18565342920; +8618565342920
sales@chembj.net China 289 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21639 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075
jack.li@time-chemicals.com China 1803 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9220 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
sales@fine-chemtech.com CHINA 885 55
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 296 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58

797-63-7(Levonorgestrel)Verwandte Suche:


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