14,15-Dihydro-14-hydroxy-eburname-nin-14-carboxylsäure-methylester,(3 alpha, 14 beta, 16 alpha),-
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- CAS-Nr.
- 1617-90-9
- Bezeichnung:
- 14,15-Dihydro-14-hydroxy-eburname-nin-14-carboxylsäure-methylester,(3 alpha, 14 beta, 16 alpha),-
- Englisch Name:
- Vincamine
- Synonyma:
- Vinca;Vraap;Perval;Equipur;Minorin;Monorin;Novicet;Pervone;Oxybral;Angiopac
- CBNumber:
- CB7344925
- Summenformel:
- C21H26N2O3
- Molgewicht:
- 354.44
- MOL-Datei:
- 1617-90-9.mol
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14,15-Dihydro-14-hydroxy-eburname-nin-14-carboxylsäure-methylester,(3 alpha, 14 beta, 16 alpha),- Eigenschaften
- Schmelzpunkt:
- 232 °C (dec.)(lit.)
- Siedepunkt:
- 487.66°C (rough estimate)
- alpha
- 42.8 º (c=1 in pyridine)
- Dichte
- 1.1640 (rough estimate)
- Brechungsindex
- 1.6500 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- Löslichkeit
- Chloroform (Slightly), DMSO (Slightly)
- Aggregatzustand
- Solid
- pka
- 12.13±0.40(Predicted)
- Farbe
- White to Off-White
- Optische Aktivität
- [α]23/D +42.8°, c = 1 in pyridine
- Merck
- 14,9983
- Stabilität:
- Hygroscopic
- LogP
- 3.100 (est)
- NIST chemische Informationen
- Vincamine(1617-90-9)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
22 |
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| S-Sätze: |
36-26 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
YY8575000 |
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| HS Code |
29399990 |
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| Giftige Stoffe Daten |
1617-90-9(Hazardous Substances Data) |
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| Toxizität |
LD50 in mice (mg/kg): 75 i.v.; >1000 s.c. (Szporny, Szász); 1000 orally (Szabo, Nagy) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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14,15-Dihydro-14-hydroxy-eburname-nin-14-carboxylsäure-methylester,(3 alpha, 14 beta, 16 alpha),- Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white to almost white fine crystalline powder
Verwenden
Vincamine is often used as a nootropic agent to combat the effects of aging, or in conjunction with other nootropics (such as piracetam) for a variety of purposes. Vincamine is a peripheral vasodilator that increases blood flow to the brain.
Weltgesundheitsorganisation (WHO)
Vincamine, an alkaloid derived from Vinca minor, is claimed to
increase cerebral circulation and utilization of oxygen. It is used in a variety of
cerebral disorders and is widely marketed for this purpose.
Allgemeine Beschreibung
Vincamine is a monoterpenoid indole alkaloid found in the leaves of
Vinca minor L., belonging to the Apocynaceae family.
14,15-Dihydro-14-hydroxy-eburname-nin-14-carboxylsäure-methylester,(3 alpha, 14 beta, 16 alpha),- Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Trimethylphosphit
Sauerstoff
Natriumhydrid
Aspidospermidin-3-carbonsure, 2,3-Didehydro-, Methylester, (5α,12β,19α)-
(3α,16α)-D-Homoeburnamenin-14,15-dion
ethyl 3-{[2-(1H-indol-3-yl)ethyl]amino}propanoate
Aspidospermidin-3-carbonsure, 2,3,6,7-Tetradehydro-, Methylester, (5α,12β,19α)-
Methanol
2-(Indol-3-yl)ethylamin
Downstream Produkte
14,15-Dihydro-14-hydroxy-eburname-nin-14-carboxylsäure-methylester,(3 alpha, 14 beta, 16 alpha),- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 450)Lieferanten
1617-90-9(14,15-Dihydro-14-hydroxy-eburname-nin-14-carboxylsäure-methylester,(3 alpha, 14 beta, 16 alpha),-)Verwandte Suche:
Ethylacrylat
ISOXADIFEN-ETHYL
Ethylpyruvat
Ethylacetat
Ethanol
Ameisensäure-ethylester
Ethyl-4-hydroxybenzoat
3,6-Bis[(4-chlor-2-phosphonophenyl)azo]-4,5-dihydroxynaphthalin-2,7-disulfonsure
Vinblastin
Vincristin
Vinpocetin
Apovincamin
N,N,1-Trimethyl-1H-pyrrol-2-methylamin
4-Aminopentyldiethylamin
1-Ethyl-2-methyl-1H-indol
Methyl-(3α,14β,16α)-14,15-dihydro-14-hydroxyeburnamenin-14-carboxylatmonohydrochlorid
14,15-Dihydro-14-hydroxy-eburname-nin-14-carboxylsäure-methylester,(3 alpha, 14 beta, 16 alpha),-
Methyl-(3α,14β,16α)-14,15-dihydro-14-hydroxyeburnamenin-14-carboxylat, [R-(R*,R*)]-Tartrat (1:1)
- (+)-cis-Vincamine
- (3alpha,14beta,16alpha)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acidmethyl ester
- (3alpha,14beta,16alpha)-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid methyl ester
- 14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid methyl ester
- Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3a,14b,16a)-
- Oxicebral
- Vincamine(8.5%)
- VINCAMINE(P)
- Methyl (3alpha,14beta,16alpha)-14-hydroxy-14,15-dihydroeburnamenine-14-carboxylate
- Methy(3α,16α)-14,15-dihydro-14β-hydroxy-eburnamenine-14-carboxylate
- 14,15-dihydro-14-hydroxyeburnamenine-14-carboxylicacidmethylester
- 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine, eburnamenine-14-carboxylic acid deriv.
- Alkaloid obtained from Vinca minor
- Anasclerol
- Anasclerol (base)
- Angiopac
- Arteriovinca
- cis-Vincamine
- Decincan
- Devincan
- Devinkan
- Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3alpha,14beta,16alpha)-
- eburnamenine-14-carboxylicacid,14,15-dihydro-14-hydroxy-,methylester,(3a
- Eburnamine-14-carboxylic acid,14,15-dihydro-14-hydroxy-, methyl ester,3alpha,14beta,16alpha)-
- Equipur
- lpha,14beta,16.)
- Methyl 14-hydroxy-14,15-dihydroeburnamenine-14-carboxylate
- Methyl vincaminate
- methylvincaminate
- Minorin
- Minorine
- Monorin
- VINCAMINE(RG)
- Vincamine (base and/or unspecified salts)
- (3aS,5S,11S)-3a-Ethyl-5-hydroxy-1,2,3,3a,4,5,10,11b-octahydro-11H-5a,11a-diaza-benzo[cd]fluoranthene-5-carboxylic acid methyl ester
- 14,15-DIHYDRO-14-HYDROXYBURNAMENINE-14-CARBOXYLIC ACID METHYL ESTER
- VINCAMINE
- VINCAMINE BASE
- Teprosilic
- VINCAMINE 98+%
- Novicet
- NSC-91998
- Ocu-vinc
- Oxygeron
- Perval
- Pervincamine
- Pervone
- Sostenil
- Tripervan
- Vinca
- Vincachron
- Vincadar
- Vinca-Ecobi
- Vincafarm
- Vincafolina
- Vincafor
- Vincagil
- Vincalen
