Pipacyclin

1110-80-1

CAS-Nr.: 1110-80-1

Bezeichnung:: Pipacyclin

Englisch Name:: pipacycline

Synonyma:: Sieromicin;Pipacicline;Mepicycline;pipacycline;Tetrasolvina;(4S)-4β-Dimethylamino-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,6α,10,12,12aβ-pentahydroxy-N-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-6-methyl-1,11-dioxo-2-naphthacenecarboxamide;2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-N-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-

CBNumber:: CB7928471

Summenformel:: C29H38N4O9

Molgewicht:: 586.638

MOL-Datei:: 1110-80-1.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 15

Pipacyclin Eigenschaften

alpha: D20 -195° (c = 0.5); D20 -175° (c = 0.5 in methanol)

Siedepunkt:: 895.8±65.0 °C(Predicted)

Dichte: 1.55±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: Soluble in DMSO

pka: 4.50±1.00(Predicted)

Sicherheit

Toxizität	LD50 i.v. in white mice: 188 mg/kg (Scalvini, Delmonte)

Pipacyclin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Pipacycline (mepicycline) is a semi-synthetic tetracycline formed by a Mannich condensation of formaldehyde and 4-hydroxyethylpiperazine with tetracycline. The introduction of the piperazine improves bioavailability, but Mannich bases are pro-drugs, converting back to the parent compound. Pipacycline is used commercially as a salt in combination with penicillin V for parenteral use (penimepicycline). The intrinsic in vitro activity and SARs for the amide region of the tetracycline molecule have not investigated extensively. Pipacycline has not been extensively cited in the literature.

Definition

ChEBI: Tetracycline in which a hydrogen attached to the amide nitrogen is substituted by a 4-[(2-hydroxyethyl)piperazin-1-yl]methyl group.

Pipacyclin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Tetracyclin Paraformaldehyde

Downstream Produkte

Pipacyclin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 15)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19743	58
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55954	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Meng Cheng Technology (Shanghai) Co., LTD	400-820-6829	sales@mitachieve.com	China	8864	58
Hubei Xinyang Medical Technology Co., Ltd	15347293736 15347293736	2853117764@qq.com	China	8594	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58

1110-80-1(Pipacyclin)Verwandte Suche:

Tetracyclin 1,2,3,4-Tetrahydro-4-methylnaphthalin-1-on alpha-Tetralol 1,2,3,4-Tetrahydronaphthalin-1,5-diol Cyclohex-1-enylmethylketon Pipacyclin

(4S)-4β-Dimethylamino-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,6α,10,12,12aβ-pentahydroxy-N-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
Mepicycline
Pipacicline
Sieromicin
Tetrasolvina
pipacycline
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-N-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-
1110-80-1
C29H38N4O9