Xylazin

Xylazine Struktur
7361-61-7
CAS-Nr.
7361-61-7
Bezeichnung:
Xylazin
Englisch Name:
Xylazine
Synonyma:
Xylazine (free base);2-(2,6-dimethylanilino)-5,6-dihydro-4h-1,3-thiazine;wh7286;Xylazin;bay1470;XYLAZINE;Mobay Rompun;Xylazine, >=99%;Xylazine powder;Xylazine(RoMpun)
CBNumber:
CB8130978
Summenformel:
C12H16N2S
Molgewicht:
220.33
MOL-Datei:
7361-61-7.mol

Xylazin Eigenschaften

Schmelzpunkt:
140 C
Siedepunkt:
334.2±52.0 °C(Predicted)
Dichte
1.0905 (rough estimate)
Brechungsindex
1.5700 (estimate)
storage temp. 
-20°C
Löslichkeit
Soluble in methanol at 50mg/ml. Also soluble in dilute acid solutions.
Aggregatzustand
Powder
pka
7.67±0.20(Predicted)
InChI
InChI=1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)
InChIKey
BPICBUSOMSTKRF-UHFFFAOYSA-N
SMILES
S1CCCN=C1NC1=C(C)C=CC=C1C
CAS Datenbank
7361-61-7(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher T,Xi
R-Sätze: 25-36/37/38
S-Sätze: 45-37/39-26
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS-Nr. XJ0776300
HazardClass  6.1
HS Code  2934990002
Toxizität LD50 in mice (mg/kg): 43 i.v.; 121 s.c.; 240 orally; LD50 in rats (mg/kg): 130 orally (Sagner)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizität oral Kategorie 3 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit

Xylazin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R25:Giftig beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Xylazine is an agonist of α2-adrenergic receptors (Ki = 194 nM). It is an analog of clonidine, an α2-adrenergic receptor agonist used to reduce blood pressure. Xylazine is used for sedation, anesthesia, and analgesia in non-human mammals. This product is also available as an analytical reference standard .

Verwenden

Xylazine is an α2 class of adrenergic receptor agonist. Xylazine is a clonidine analoque that acts on presynaptic and postsynaptic receptors as an a 2-adrenergic agonist.

Allgemeine Beschreibung

Xylazine is soluble in methanol (50 mg/ml), yielding a clear, colorless solution. It is also soluble in dilute HCl acid and in chloroform. Xylazine is practically insoluble in water and in alkali solutions.

Mechanism of action

Xylazine is marketed as its hydrochloride salt as Rompun (100 mg/mL) and Anased (20 mg/mL) injectable solutions for intravenous administration to horses and dogs, respectively. The actions of xylazine may be reversed by the administration of yohimbine, an indolalkylamine alkaloid, that blocks those α2- adrenoreceptors that are stimulated by xylazine.

Nebenwirkungen

High doses of Xylazine can cause dizziness, vomiting, high blood sugar, blurry vision and even overdose deaths. If you inject xylazine into your body, you also may develop skin ulcers and severe wounds that can spread and worsen quickly. Xylazine can lead to depression of the central nervous system along with other adverse effects. As for animals, they may show profound salivation following an injection with xylazine. Other adverse effects for dogs and cats include: muscle tremors, bradycardia with AV-block, hypotension, reduced respiratory rate, movement in response to strong auditory stimuli, and increased urination in cats.

Sicherheitsprofil

Poison by ingestion, subcutaneous, and intravenous routes. Human systemic effects: change in motor activity, fall in blood pressure, miosis, pleural thickening, pulse rate decrease, somnolence. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Xylazin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

7361-61-7(Xylazin)Verwandte Suche:


  • 2-(2,6-dimethylphenylamino)-4h-5,6-dihydro-1,3-thiazine
  • 5,6-dihydro-2-(2,6-xylidino)-4h-1,3-thiazine
  • 5,6-dihydro-2-(2,6-xylidino)-4h-3-thiazine
  • 2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine
  • Xylazine Base & HCL
  • Xylazine,2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride
  • Xylazine (200 mg)
  • Xylazine(RoMpun)
  • (5,6-Dihydro-4H-[1,3]thiazin-2-yl)-(2,6-diMethyl-phenyl)-aMine, N-(2,6-DiMethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-aMine
  • Xylazine N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
  • Xylazine, >=99%
  • Xylazin
  • bay1470
  • n-(2,6-dimethylphenyl)-5,6-dihydro-4h-3-thiazine-2-amine
  • n-(5,6-dihydro-4h-1,3-thiazinyl)-6-xylidine
  • wh7286
  • N-(2,6-DIMETHYLPHENYL)-5,6-DIHYDRO-4H-1,3-THIAZIN-2-AMINE
  • XYLAZINE
  • 2-[2,6-DIMETHYLPHENYLAMINO]-4H-5,6-DIHYDROTHIAZINE
  • (5,6-DIHYDRO-4H-[1,3]THIAZIN-2-YL)-(2,6-DIMETHYLPHENYL)-AMINE
  • AKOS BBS-00000613
  • XYLAZINE HYDROCHLORIDE A2 ADRENOCEPTOR A GONI
  • XYLAZINE, IMPURITY EN-(2,6-DIMETHYLPHENYL)-S-METHYLDITHIOUREA EP STANDARD
  • XYLAZINE, USP STANDARD
  • XYLAZINE, IMPURITY C2,6-DIMETHYLPHENYL ISOTHIOCYANATE EP STANDARD
  • 4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-
  • XYLAZINE HCL/BASE
  • 1,3-THIAZINE,5,6-DIHYDRO-2-(2,6-XYLIDINO)-
  • xylazine free base
  • (5,6-Dihydro-4H-[1,3]thiazin-2-yl)-(2,6-dimethyl-p
  • Mobay Rompun
  • 2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-1,3-thiazine
  • 3-benzodioxole-5-carboxylic acid
  • Xylazine (1720407)
  • Xylazine with lowest price(WhatsApp+8619930501653
  • Xylazine 7361-61-7
  • Xylazine / Xylazine hydrochloride
  • Xylazine USP/EP/BP
  • Xylazine powder
  • Xylazine Basic information
  • Xylazine Pharmaceutical Intermediates
  • Xylazine HCL hydrochloride
  • xylazine hcl Veterinary drugs
  • High Quality Adrenoceptor Agonists Xylazine
  • Xylazine white Crystal
  • 2(-2,6-Dimethylphenylamino)-5
  • Trimethothiazine
  • 2-(2,6-dimethylanilino)-5,6-dihydro-4h-1,3-thiazine
  • Xylazine (free base)
  • Keratin hydrolyzed 69430-36-0
  • Xylazine ready stock
  • Xylazine in Acetonitrile
  • 7361-61-7
  • 7361-61-7
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