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Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz

Bucladesine sodium Struktur
16980-89-5
CAS-Nr.
16980-89-5
Bezeichnung:
Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz
Englisch Name:
Bucladesine sodium
Synonyma:
DC 2797;,5ÕDBcAMP-Na;N6-2ÕPrestwick_32;CAMP, DB-, NA;BUCLADESINE NA;dt5621sodiumsalt;DIB-3:5-CAMP, NA;bucladesinesodium
CBNumber:
CB8236166
Summenformel:
C18H25N5NaO8P
Molgewicht:
493.39
MOL-Datei:
16980-89-5.mol
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Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz Eigenschaften

Schmelzpunkt:
>173°C (dec.)
storage temp. 
-20°C
Löslichkeit
H2O: 50 mg/mL
Aggregatzustand
powder
Farbe
white
Merck 
14,1463
Stabilität:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChIKey
DBXVIQJWMFGXGO-AOTDUVMNNA-N
SMILES
O([C@@H]1[C@]2([H])OP(O)(=O)OC[C@@]2([H])O[C@H]1N1C=NC2C(=NC=NC1=2)NC(=O)CCC)C(=O)CCC.[NaH] |&1:1,2,10,13,r|
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
S-Sätze: 24/25
WGK Germany  2
RTECS-Nr. ES5055500
F  10-21
HS Code  29349990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Bucladesine sodium is a derivative of cyclic-AMP with cardiac stimulant and peripheral vasodilatory properties. It is reported to be useful in cardiac insufficiency, especially after heart surgery.

Verwenden

Bucladesine sodium is an analog of cyclic AMP that stimulates cAMP-dependent protein kinase. It has vasodilator properties and is used as a cardiac stimulant.

Application

N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt has been used:
as a medium supplement for neural crest stem cells (NCSCs) differentiation
as a component of thawing medium for cryopreserved human iPSC (induced pluripotent stem cell)-derived neurons
in serum-free Dulbecco′s modified eagle′s medium (DMEM) to induce astrocyte differentiation

Definition

ChEBI: Bucladesine sodium is a 3',5'-cyclic purine nucleotide.

Allgemeine Beschreibung

A cell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (PKA). Causes an increase in the steady state level of parathyroid hormone-related peptide mRNA. Also acts as a Hh pathway antagonist. Shown to induce apoptosis in vascular smooth muscle cells.

Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 327)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
HangZhou RunYan Pharma Technology Co.,LTD.
+86-88660901 +86-18112526015
 sales@runyanpharma.com China 326 58
Hangzhou Meiya Pharmaceutical Co Ltd
+86-021-33686691 +8618001850931
 sales@meiyapharm.com China 57 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177
 peter@yan-xi.com China 6011 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32686 60
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linda@hubeijusheng.com CHINA 22968 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Shanghai Longyu Biotechnology Co., Ltd. 		+8615821988213
 info@longyupharma.com China 2531 58

16980-89-5(Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz)Verwandte Suche:

Nadid Butyramid Adenosin-3',5'-phosphatmonohydrat Bucladesin Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz
  • dibutylcyclicampsodium
  • dibutylcyclicampsodiumsalt
  • dt5621sodiumsalt
  • e,butyrate(ester),monosodiumsalt
  • monosodiumdibutyrylcyclicamp
  • n-(9-beta-d-ribofuranosyl-9h-purin-6-yl)-butyramidcyclichydrogenphosphat
  • n6,02’-dibutyryladenosine3’,5’-cyclicmonophosphatesodiumsalt
  • n6,2’-o-dibutyryladenosine-3’,5’-cyclicmonophosphate(dbcamp),sodiumsalt
  • N,2'-O-Dibutanoyladenosine 3',5'-(phosphoric acid sodium) salt
  • N,2'-O-Dibutyryladenosine-3',5'-phosphoric acid sodium salt
  • Sodium bucladesine
  • ,5Õ
  • -cyclophosphate sodium salt monohydrate
  • N6-2Õ
  • -O-Dibutyryl-adenosine 3Õ
  • Adenosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, monosodium salt
  • Calcium Dibutyacyladenosine Cyclophosphate
  • N6,2'-O-DIBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHA
  • N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLO-P HOSPHATE SO-SALT
  • Dibutyacyladenosine
  • 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv.
  • Butyramide, N-(9-b-D-ribofuranosyl-9H-purin-6-yl)-, cyclic hydrogen phosphate butyrate (ester), monosodium salt (8CI)
  • DC 2797
  • Dibutyryl 3',5'-cyclic AMP sodium salt
  • Dibutyryl cyclic AMP monosodium salt
  • Dibutyryl cyclic AMP sodium
  • N6,2'-O-Dibutyryl-3',5'-cyclic AMP sodium salt
  • N6,2'-O-Dibutyryladenosine-3',5'-monophosphate monosodium salt
  • N6,O2'-Dibutyryl-3',5'-cyclic AMP sodium salt
  • N-6,O-2'-Dibutyryladenosine cyclic 3',5'-monophosphate sodium salt
  • Sodium N6,2'-O-dibutyryladenosine 3',5'-cyclic phosphate
  • DIBUTYRYL-CYCLICAMP
  • BUCLADESINE[N-6,O-2''-DIBUTYRYL ADENOSINE CYCLIC 3'',5''-MONOPHOSPHATE]
  • N6,2'-O-DIBUTRYL-ADENISINE-3',5'-CYCLICMONPHOSPHATE SODIUM SALT
  • Bucladesine sodium salt, Dibutyryl cAMP sodium salt, Dibutyryl cyclic-AMP sodium salt
  • Bucladesine, Dibutyryl cyclic-AMP
  • N6,2μ-O-Dibutyryladenosine 3μ,5μ-cyclic monophosphate monohydrate sodium salt
  • ibutyryl cyclic AMP sodium
  • N6,O2-DIBUTYRYLADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE NA
  • Dibutyacyladenosine cyclphosphate
  • Adenosine,N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, sodiuM salt(1:1)
  • Adenosine 3?,5?-cyclic Monophosphate, N?,O
  • Dibutyryl-cAMP sodium salt, >=98%
  • adenosine,n-(1-oxobutyl)-,cyclic3’,5’-(hydrogenphosphate)-2’-butanoate,m
  • bucladesinesodium
  • butyramide,n-(9-beta-d-ribofuranosyl-9h-purin-6-yl)-,cyclichydrogenphosphate,butyrate(ester),monosodiumsalt
  • dibutylcampsodiumsalt
  • sodiumdibutyryl3’,5’-cyclicamp
  • sodiumdibutyrylcamp
  • N6, O2-DIBUTYRYLADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE SODIUM SALT
  • N6,O2'-DIBUTYRYL ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • N6,O2'-DIBUTYRYLADENOSINE-3':5'-PHOSPHATE CYCLIC NA-SALT
  • N6,O2'-DIBUTYRYLADENOSINE-3',5'-PHOSPHATE CYCLIC SODIUM SALT
  • N6,2'-O-DIBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • N6,2'-O-DIBUTYRYLADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID, SODIUM
  • ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, N6,O2'-DIBUTYRYL-, SODIUM SALT
  • ADENOSINE-3',5'-CYCLIC MONOPHOSPHORIC ACID, N,2'O-DIBUTYRYL, SODIUM SALT
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