7,8-DIHYDRO-L-BIOPTERIN
- CAS No.
- 6779-87-9
- Chemical Name:
- 7,8-DIHYDRO-L-BIOPTERIN
- Synonyms
- BH2;DIHYDROBIOPTERIN;7,8-dihydrobiopterin;Biopterin Impurity 1;Biopterin impurity 6;7,8-DIHYDRO-L-BIOPTERIN;Sapropterin Impurity 18;L-erythro-Dihydrobiopterin;L-erythro-7,8-Dihydrobiopterin;2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydro-1H-pteridin-4-one
- CBNumber:
- CB0320957
- Molecular Formula:
- C9H13N5O3
- Molecular Weight:
- 239.23
- MDL Number:
- MFCD07375453
- MOL File:
- 6779-87-9.mol
- MSDS File:
- SDS
| Melting point | >300°C dec. |
|---|---|
| Boiling point | 470.8±55.0 °C(Predicted) |
| Density | 1.88 |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | Aqueous Acid (Slightly, Sonicated), Aqueous Base (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | 10.47±0.20(Predicted) |
| color | Pale Yellow to Brown |
| BRN | 536551 |
| Stability | Hygroscopic |
| InChIKey | FEMXZDUTFRTWPE-AWFVSMACSA-N |
| CAS DataBase Reference | 6779-87-9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| F | 3-10 |
7,8-DIHYDRO-L-BIOPTERIN price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 37272 | 7,8-Dihydro-L-biopterin ≥94% (HPLC) | 6779-87-9 | 10mg | $121 | 2024-03-01 | Buy |
| Sigma-Aldrich | 37272 | 7,8-Dihydro-L-biopterin ≥94% (HPLC) | 6779-87-9 | 50mg | $470 | 2024-03-01 | Buy |
| Cayman Chemical | 81882 | 7,8-dihydro-L-Biopterin ≥97% | 6779-87-9 | 5mg | $45 | 2024-03-01 | Buy |
| Cayman Chemical | 81882 | 7,8-dihydro-L-Biopterin ≥97% | 6779-87-9 | 10mg | $72 | 2024-03-01 | Buy |
| Cayman Chemical | 81882 | 7,8-dihydro-L-Biopterin | 6779-87-9 | 50mg | $330 | 2024-03-01 | Buy |
7,8-DIHYDRO-L-BIOPTERIN Chemical Properties,Uses,Production
Description
BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.
Chemical Properties
Yellow Powder
Uses
BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.
Uses
An oxidation producct of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of G
Uses
The reduced form of Biopterin. An oxidation product of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.
Definition
ChEBI: L-erythro-7,8-dihydrobiopterin is a 7,8-dihydrobiopterin in which the 1,2-dihydroxypropyl group has (1R,2S)-configuration; naturally occurring form. It is an enantiomer of a D-erythro-7,8-dihydrobiopterin.
References
[1] shen r, alam a, zhang y. inhibition of gtp cyclohydrolase i by pterins[j]. biochimica et biophysica acta (bba)-general subjects, 1988, 965(1): 9-15.
[2] sugiyama t, levy b d, michel t. tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells[j]. journal of biological chemistry, 2009, 284(19): 12691-12700.
7,8-DIHYDRO-L-BIOPTERIN Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 18958018566; | info@afinechem.com | China | 15377 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9923 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |