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BMS-986205

CAS No.
1923833-60-6
Chemical Name:
BMS-986205
Synonyms
Linrodostat;CS-2743;F001287;F-001287;BMS-986205;BMS 986205;BMS986205;Linrodostat(BMS-986205);BMS-986205(Linrodostat);LINRODOSTAT;BMS 986205;BMS986205;(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid
CBNumber:
CB03339862
Molecular Formula:
C24H24ClFN2O
Molecular Weight:
410.91
MDL Number:
MFCD31619233
MOL File:
1923833-60-6.mol
Last updated:2023-05-21 10:59:17

BMS-986205 Properties

Boiling point 606.8±45.0 °C(Predicted)
Density 1?+-.0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:42.0(Max Conc. mg/mL);73.75(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);175.59(Max Conc. mM)
pka 13.80±0.70(Predicted)
FDA UNII 0A7729F42K
NCI Drug Dictionary linrodostat

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

BMS-986205 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B596415 BMS-986205 1923833-60-6 10mg $1890 2021-12-16 Buy
Biosynth Carbosynth BB165429 BMS 986205 1923833-60-6 50mg $507.5 2021-12-16 Buy
Biosynth Carbosynth BB165429 BMS 986205 1923833-60-6 10mg $145 2021-12-16 Buy
ChemScene CS-0021719 Linrodostat 99.92% 1923833-60-6 5mg $156 2021-12-16 Buy
ChemScene CS-0021719 Linrodostat 99.92% 1923833-60-6 10mg $288 2021-12-16 Buy
Product number Packaging Price Buy
B596415 10mg $1890 Buy
BB165429 50mg $507.5 Buy
BB165429 10mg $145 Buy
CS-0021719 5mg $156 Buy
CS-0021719 10mg $288 Buy

BMS-986205 Chemical Properties,Uses,Production

Description

BMS-986205, also known as Linrodostat, ONO-7701 and F001287, a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities.

Biological Activity

Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.

Uses

BMS-986205 is a compound being studied for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders.

BMS-986205 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 99)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Biochempartner
0086-13720134139 candy@biochempartner.com CHINA 967 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hangzhou Proserre Chemical Co.,Ltd.
+86-571-86088112 info@proserre.com China 1077 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58

View Lastest Price from BMS-986205 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BMS-986205 pictures 2022-02-19 BMS-986205
1923833-60-6
US $0.00 / gram 1gram 99% 10kg Zhejiang J&C Biological Technology Co.,Limited
  • BMS-986205 pictures
  • BMS-986205
    1923833-60-6
  • US $0.00 / gram
  • 99%
  • Zhejiang J&C Biological Technology Co.,Limited
BMS-986205 LINRODOSTAT;BMS 986205;BMS986205 BMS 986205;BMS986205 BMS-986205(Linrodostat) CS-2743 (2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methyl-, cis-(αR)- Linrodostat (R)-N-(4-Chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide Linrodostat(BMS-986205) cis-(αR)-N-(4-Chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methylcyclohexaneacetamide cis-(alphaR)-N-(4-Chlorophenyl)-4-(6-fluoro-quinolin-4-yl)-alpha-methylcyclohexaneacetamide F001287 F-001287 1923833-60-6 923833-60-6 C24H24ClFN2O API