Clobetasone butyrate
- CAS No.
- 25122-57-0
- Chemical Name:
- Clobetasone butyrate
- Synonyms
- eumovate;Clobetasone-17-butyrate;sn203;Emovate;CCl 5537;molivate;GR 2/1214;Kindavate;(16-beta)-);17-Butyrate
- CBNumber:
- CB0497976
- Molecular Formula:
- C26H32ClFO5
- Molecular Weight:
- 478.98
- MDL Number:
- MFCD00133196
- MOL File:
- 25122-57-0.mol
- MSDS File:
- SDS
Melting point | 90-100° |
---|---|
Boiling point | 573.3±50.0 °C(Predicted) |
Density | 1.1736 (estimate) |
storage temp. | Refrigerator, Under Inert Atmosphere |
solubility | Practically insoluble in water, freely soluble in acetone and in methylene chloride, slightly soluble in ethanol (96 per cent). |
color | White to Off-White |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
InChIKey | FBRAWBYQGRLCEK-JGSYYNBSNA-N |
SMILES | [C@]1(C(=O)CCl)(OC(=O)CCC)[C@@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@]12C |&1:0,11,14,16,26,28,33,r| |
CAS DataBase Reference | 25122-57-0(CAS DataBase Reference) |
FDA UNII | 8U0H6XI6EO |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
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Signal word | Warning | |||||||||
Hazard statements | H351 | |||||||||
Precautionary statements | P280 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 40 | |||||||||
Safety Statements | 22-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | TU4154083 | |||||||||
HS Code | 29372290 | |||||||||
Toxicity | mouse,LD50,intraperitoneal,500mg/kg (500mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 838, 1983. | |||||||||
NFPA 704 |
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Clobetasone butyrate price More Price(21)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C5548 | Clobetasone butyrate ≥98% | 25122-57-0 | 100mg | $61.9 | 2024-03-01 | Buy |
Sigma-Aldrich | C2285000 | Clobetasone butyrate European Pharmacopoeia (EP) Reference Standard | 25122-57-0 | c2285000 | $153 | 2024-03-01 | Buy |
TCI Chemical | C3510 | Clobetasone Butyrate >98.0%(HPLC) | 25122-57-0 | 50mg | $30 | 2024-03-01 | Buy |
TCI Chemical | C3510 | Clobetasone Butyrate >98.0%(HPLC) | 25122-57-0 | 250mg | $194 | 2024-03-01 | Buy |
Sigma-Aldrich | Y0001137 | Clobetasone butyrate for system suitability European Pharmacopoeia (EP) Reference Standard | 25122-57-0 | y0001137 | $150 | 2024-03-01 | Buy |
Clobetasone butyrate Chemical Properties,Uses,Production
Chemical Properties
White or almost white powder.
Uses
Clobetasone butyrate is a synthetic glucocorticoid which is used as an anti-inflammatory in the treatment of various skin disorders. As a steroid medicine, it can used on the skin to treat swelling, itching and irritation. Such as eczema, including ;contact dermatitis; psoriasis; insect bites and stings; nappy rash.
Definition
ChEBI: Clobetasone butyrate is an organic molecular entity.
Mechanism of action
Topical corticosteroids (Clobetasone butyrate) inhibit the migration of macrophages and leukocytes into areas of inflamed skin by reversing vascular dilation and permeability, resulting in decreased erythema, edema and pruritus.
Side effects
Some people get a burning or stinging feeling for a few minutes when they put clobetasone cream or ointment on their skin. Clobetasone cream contains cetostearyl alcohol and chlorocresol, which may cause local skin reactions or allergic reactions.
Clobetasone butyrate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12466 | 58 |
Hebei Duling International Trade Co. LTD | +8617333973358 | sales01@hbduling.cn | China | 15547 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8829 | 58 |
Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 968 | 58 | |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
View Lastest Price from Clobetasone butyrate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-06-05 | Clobetasone butyrate
25122-57-0
|
US $60.00 / kg | 1kg | 99% | 100 tons/month | Hebei Duling International Trade Co. LTD | ||
2023-09-06 | Clobetasone butyrate
25122-57-0
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | ||
2023-08-22 | Clobetasone butyrate
25122-57-0
|
US $25.00 / kg | 1kg | 99% | 100tons | Anhui Ruihan Technology Co., Ltd |
- Clobetasone butyrate
25122-57-0
- US $60.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
- Clobetasone butyrate
25122-57-0
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
- Clobetasone butyrate
25122-57-0
- US $25.00 / kg
- 99%
- Anhui Ruihan Technology Co., Ltd