Molnupiravir
- CAS No.
- 2492423-29-5
- Chemical Name:
- Molnupiravir
- Synonyms
- Molnupiravir-001-QA;Molnupiravir In-House;Uridine, 4-oxime, 5'-(2-methylpropanoate), (4Z)-;Molnupiravir D7Q: What is Molnupiravir D7 Q: What is the CAS Number of Molnupiravir D7;(2R,3S,4R,5R)-3,4-dihydroxy-5-[(4Z)-4-hydroxyimino-2-oxo-pyrimidin-1-yl]tetrahydrofuran-2-yl]methyl 2-methylpropanoate;((2R,3S,4R,5R)-3,4-Dihydroxy-5-((Z)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate;MolnupiravirQ: What is Molnupiravir Q: What is the CAS Number of Molnupiravir Q: What is the storage condition of Molnupiravir;((2R,3S,4R,5R)-3,4-Dihydroxy-5-((Z)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate (Molnupiravir Impurity)
- CBNumber:
- CB08369543
- Molecular Formula:
- C13H19N3O7
- Molecular Weight:
- 329.31
- MDL Number:
- MFCD32663515
- MOL File:
- 2492423-29-5.mol
| Density | 1.62±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMSO : 100 mg/mL (303.67 mM; Need ultrasonic) |
| pka | 6.71±0.20(Predicted) |
| FDA UNII | YA84KI1VEW |
Molnupiravir price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114880 | Molnupiravir 99.94% | 2492423-29-5 | 200mg | $450 | 2021-12-16 | Buy |
| ChemScene | CS-0114880 | Molnupiravir 99.94% | 2492423-29-5 | 500mg | $950 | 2021-12-16 | Buy |
| ChemScene | CS-0114880 | Molnupiravir 99.94% | 2492423-29-5 | 1g | $1550 | 2021-12-16 | Buy |
| ChemScene | CS-0114880 | Molnupiravir 99.94% | 2492423-29-5 | 25mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-0114880 | Molnupiravir 99.94% | 2492423-29-5 | 50mg | $150 | 2021-12-16 | Buy |
Molnupiravir Chemical Properties,Uses,Production
Description
Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection.
Definition
ChEBI: Molnupiravir is a nucleoside analogue that is N(4)-hydroxycytidine in which the 5'-hydroxy group is replaced by a (2-methylpropanoyl)oxy group. It is the prodrug of the active antiviral ribonucleoside analog N(4)-hydroxycytidine (EIDD-1931), has activity against a number of RNA viruses including SARS-CoV-2, MERS-CoV, and seasonal and pandemic influenza viruses. It is currently in phase III trials for the treatment of patients with COVID-19. It has a role as a prodrug, an anticoronaviral agent and an antiviral drug. It is a nucleoside analogue, an isopropyl ester and a ketoxime. It is functionally related to a N(4)-hydroxycytidine.
Biological Activity
Molnupiravir is a broad-spectrum antiviral prodrug of the nucleoside analog β-D-N4-hydroxycytidine (NHC). It competes predominantly with CTP for incorporation; it induces lethal viral mutagenesis by increasing G to A and C to U transition mutations without inhibition of RNA synthesis in replicating coronaviruses, which prevents the development of viral resistance. In primary airway epithelial cell cultures, Molnupiravir dose-dependently inhibits SARS-CoV-2 infectious virus production; it also inhibits MERS-CoV and SARS-CoV with EC50 values in the submicromolar range. In mice infected with SARS-CoV or MERS-CoV, it improves pulmonary function, and reduces virus titer and body weight loss. Molnupiravir also displays in vivo efficacy against seasonal and pandemic influenza A shed virus. It is orally bioavailable.
storage
Store at -20°C
Molnupiravir Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Proserre Chemical Co.,Ltd. | +86-571-86088112 | info@proserre.com | China | 1077 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Nanjing Shizhou Biotechnology Co., Ltd | +86-15850508050 +86-15850508050 | sean.lv@synzest.com | China | 323 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28404 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 18958018566; | info@afinechem.com | China | 15377 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 19949 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4604 | 58 |
| Jinan Chenghui Shuangda biological Co., LTD | 0531-58897003 15550412551 | market@jnchsd.com | China | 217 | 62 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9756 | 58 |
View Lastest Price from Molnupiravir manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-05-14 | Uridine, 4-oxime, 5'-(2-methylpropanoate), (4Z)-
2492423-29-5
|
US $1.10 / g | 1g | 99.9% Min | 100 Tons | Dideu Industries Group Limited |
-
- Uridine, 4-oxime, 5'-(2-methylpropanoate), (4Z)-
2492423-29-5
- US $1.10 / g
- 99.9% Min
- Dideu Industries Group Limited