ChemicalBook >> CAS DataBase List >>Selamectin

Selamectin

Selamectin structure

CAS No.: 220119-17-5

Chemical Name:: Selamectin

Synonyms: Skudin;Stronghold;Selamectin;Selamection;Selamectin（b）;Selamectin CRS;hypnocarpic acid;Sierra rhzomorph;selamectin ceutical;Selamectin (1611729)

CBNumber:: CB0947411

Molecular Formula:: C43H63NO11

Molecular Weight:: 769.97

MDL Number:: MFCD31621085

MOL File:: 220119-17-5.mol

Last updated:2024-04-26 14:50:00

Request For Quotation

Selamectin Properties

Melting point	>180°C
Boiling point	917.0±65.0 °C(Predicted)
Density	1.35±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Dichloromethane (Slightly, Heated), DMSO (Slightly)
pka	10.34±0.70(Predicted)
color	White to Yellow
Stability	Hygroscopic
InChIKey	AFJYYKSVHJGXSN-KAJWKRCWSA-N
CAS DataBase Reference	220119-17-5
FDA UNII	A2669OWX9N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H413
Precautionary statements	P273-P501
WGK Germany	3
HS Code	2932206000

Selamectin price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	32476	Selamectin VETRANAL	220119-17-5	10mg	$575	2024-03-01	Buy
Sigma-Aldrich	1611729	Selamectin United States Pharmacopeia (USP) Reference Standard	220119-17-5	350mg	$2150	2024-03-01	Buy
Cayman Chemical	21529	Selamectin ≥98%	220119-17-5	1mg	$32	2024-03-01	Buy
Cayman Chemical	21529	Selamectin ≥98%	220119-17-5	5mg	$122	2024-03-01	Buy
Cayman Chemical	21529	Selamectin ≥98%	220119-17-5	10mg	$184	2024-03-01	Buy

Product number	Packaging	Price	Buy
32476	10mg	$575	Buy
1611729	350mg	$2150	Buy
21529	1mg	$32	Buy
21529	5mg	$122	Buy
21529	10mg	$184	Buy

Selamectin Chemical Properties,Uses,Production

Description

Selamectin is formulated as a spot-on for cats and dogs to control fleas (Ctenocephalides spp.) and flea-allergy dermatitis, to prevent heartworm disease, and to control ear mites (Otodectes cynotes) in cats and dogs. It is also approved for the treatment and control of sarcoptic mange (Sarcoptes scabiei) in dogs and hookworms (Ancylostoma tubaeformis) and roundworms (Toxocara cati) in cats.

Description

Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. At 0.1 μg/ml, selamectin is reported to inhibit growth in an H. contortus larval development assay.

Uses

Selamectin is a topical parasiticide and also used as a veterinary antihelminithic agent on animals.

Uses

Selamectin is a semi-synthetic avermectin derivative prepared by selective hydrolysis and oximation of doramectin. Selamectin is a potent nematocide used for the treatment of endo- and exo- parasites of domestic animals, notably cats and dogs. Like the other milbemycin/avermectins, selamectin selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite.

Definition

ChEBI: Selamectin is a milbemycin.

Veterinary Drugs and Treatments

Topical selamectin (Revolution?—Pfizer) is indicated for flea infestations (Ctenocephalides felis), prevention of heartworm disease (Dirofilaria immitis), and for ear mites (Otodectes cynotis) in both dogs and cats. Additionally in dogs, it is indicated for sarcoptic mange (Sarcoptes scabeii), and tick infestations (Dermacentor variabilis). In cats: hookworm (Ancylostoma tubaeforme) and roundworm (Toxocara cati). The product (Revolution?) is labeled as not effective against either adult heartworms or clearing circulating microfilaria, but it possibly may have some efficacy with prolonged, continuous administration (Atkins 2007b).

Toxicity evaluation

Acute oral LD₅₀ for rats: >1,600 mg/kg

Selamectin Preparation Products And Raw materials

Raw materials

Preparation Products

Selamectin Suppliers

Global( 241)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ENBRIDGE PHARMTECH CO., LTD.	+8613812269233	tinayang@enbridgepharm.com	China	303	58
AFINE CHEMICALS LIMITED	0571-85134551 18958018566;	info@afinechem.com	China	15377	58
Henan Tengmao Chemical Technology Co. LTD	+8615238638457	salesvip2@hntmhg.com	China	415	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	18229	58
Sigma Audley	+86-18336680971 +86-18126314766	nova@sh-teruiop.com	China	525	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	sarah@tnjone.com	China	1125	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	3001	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9341	55

Supplier	Advantage
ENBRIDGE PHARMTECH CO., LTD.	58
AFINE CHEMICALS LIMITED	58
Henan Tengmao Chemical Technology Co. LTD	58
Anhui Ruihan Technology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Sigma Audley	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55

View Lastest Price from Selamectin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-05-08	Selamectin 220119-17-5	US $0.00 / Kg/Bag	2Kg/Bag	99% up, High Density	20 tons	Sinoway Industrial co., ltd.
2024-04-23	Selamectin 220119-17-5	US $5.00 / kg	1kg	99.92%	50000tons	Ouhuang Engineering Materials (Hubei) Co., Ltd
2024-04-16	Selamectin 220119-17-5	US $9000.00 / g	100g	99%	10kg	Hebei ZB Gamay Biological Technology Co.,Ltd

Selamectin
220119-17-5
US $0.00 / Kg/Bag
99% up, High Density
Sinoway Industrial co., ltd.

Selamectin
220119-17-5
US $5.00 / kg
99.92%
Ouhuang Engineering Materials (Hubei) Co., Ltd

Selamectin
220119-17-5
US $9000.00 / g
99%
Hebei ZB Gamay Biological Technology Co.,Ltd

Selamectin Spectrum

Selamectin(220119-17-5)¹HNMR

220119-17-5(Selamectin)Related Search:

Diaquo[(1R,2R)-1,2-cyclohexanediaMine]platinuM DiMer Dinitrate OXALIC ACID Nitroclofene acepromazine Imidacloprid

Amitraz Moxidectin Ascomycin Succinylcholine Chloride Terbinafine Hydrochloride

Selamectin FEMA 3693

1of3

Selamectin AverMectin A1a,25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-Methyl-a-L-arabino-hexopyranosyl)-5-deMethoxy-25-de(1-Methylpropyl)-22,23-dihydro-5-(hydroxyiMino)-,(5Z)- hypnocarpic acid (5Z)-25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a Revolution (antibiotic) Stronghold Selamectin CRS Avermectin A1a, 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-, (5Z)- Oxaliplatin Impurity5（EP Impurity D） selamectin ceutical Avermectin A1a, 25-cyclohexyl-4-O-de(2,6-dideoxy-3-O-methyl-... Selamection Selamectin (1611729) Sierra rhzomorph Skudin (2R,2a'E,2a1'S,4'E,5S,6S,6'S,7'S,8'E,11'R,15'S,17a'R,20'Z,20a'R)-6-Cyclohexyl-2a1'-hydroxy-7'-(((2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-20'-(hydroxyimino)-5,6',8',19'-tetramethyl-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one Selamectin（b） (2R,2a'E,2a1'S,4'E,5S,6S,6'S,7'S,8'E,11'R,15'S,17a'R,20'Z,20a'R)-6-Cyclohexyl-2a1'-hydroxy-7'-(((2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-20'-(hydroxyimino)-5,6',8',19'-tetramethyl-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one 220119-17-5 C43H63NO11 Anthelmintic ectoparasiticide API 220119-17-5