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1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE

CAS No.
943-88-4
Chemical Name:
1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE
Synonyms
NSC31752;AI3-00222;NSC-31752;NSC 31752;ANISALACETONE;p-Anisalacetone;anisylideneacetone;Ani-sylideneacetone;p-Anisilidenacetone;p-Anisylideneacetone
CBNumber:
CB1245673
Molecular Formula:
C11H12O2
Molecular Weight:
176.21
MDL Number:
MFCD00017251
MOL File:
943-88-4.mol
Last updated:2024-03-28 13:39:29

1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE Properties

Melting point 75-77°
Boiling point 267.83°C (rough estimate)
Density 1.0558 (rough estimate)
refractive index 1.5100 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Very Slightly)
form Solid
color White or yellowish leafy crystals.
LogP 2.25
EWG's Food Scores 1-3
FDA UNII 79U9LYF10I
EPA Substance Registry System 3-Buten-2-one, 4-(4-methoxyphenyl)- (943-88-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT
HS Code  2914500090
Toxicity Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg (Wohl, 1974).

1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M226670 4-(4-Methoxyphenyl)-3-buten-2-one 943-88-4 5g $720 2021-12-16 Buy
Apolloscientific OR26402 4-(4-Methoxyphenyl)but-3-en-2-one 943-88-4 5g $492 2021-12-16 Buy
Matrix Scientific 043222 4-(4-Methoxyphenyl)-3-buten-2-one >95% 943-88-4 5g $285 2021-12-16 Buy
SynQuest Laboratories 2917-1-44 4-(4-Methoxyphenyl)but-3-en-2-one 943-88-4 5G $365 2021-12-16 Buy
Matrix Scientific 043222 4-(4-Methoxyphenyl)-3-buten-2-one >95% 943-88-4 500mg $53 2021-12-16 Buy
Product number Packaging Price Buy
M226670 5g $720 Buy
OR26402 5g $492 Buy
043222 5g $285 Buy
2917-1-44 5G $365 Buy
043222 500mg $53 Buy

1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE Chemical Properties,Uses,Production

Aroma

Slightly pungent, but in dilution sweet, floral and creamy odor of considerable tenacity. 
1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE, like many related ketones, has met with much resistance from perfumers and dermatologists. However, it has survived all attacks under the usual and probably reasonable argument, that in normal concentrations, it will have no harmful effects on the human skin. Undoubtedly, perfumers are using scores of materials with a much shorter history of successful application.
It finds use in many floral perfume compositions, mainly Cassie bases, Acacia, Lilac, Sweet Pea, Hyacinth, etc. In even lower concentration, it may give interesting effects in Lavender, Fougeres, New Mown Hay (for which it was originally intended), etc.

Occurrence

Has apparently not been reported to occur in nature.

Uses

4-(4-methoxyphenyl)-3-buten-2-one is used in preparation of Thiazole derivatives as protein secretion inhibitors.

Preparation

From anisaldehyde and acetone by condensation using a suitable catalyst.

Metabolism

When the side chain of a mixed ketone contains a double bond, both the keto group and the double bond are potentially reducible in vivo. In a related material, methyl styryl ketone ( C6 H5 CH:CHCOCH3 ) , the keto group appears to be more readily reduced than the double bond,with reduction via C6 H5 CH:CH.CH(OH)CH3to the completely reduced carbinol compoundC6 H5[CH2]2CH(OH) CH3, which is found as the main product (Fischer & Bielig, 1940). The ether link is relatively stable in substituted anisoles, such as anethole (p-CH3OC 6H4CH:CH CH4), containinga potential carboxyl group attached to the aromatic ring (Williams, 1959).

1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32715 60
career henan chemical co
+86-0371-86658258 15093356674; sales@coreychem.com China 29914 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
ShenZhen H&D Pharmaceutical Technology Co., LTD
+86-0755-22677845 +86-13627253706 sale@hdimpurity.com China 2432 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131980 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35906 56

View Lastest Price from 1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dobutamine Impurity 25 pictures 2024-03-29 Dobutamine Impurity 25
943-88-4
US $0.00 / mg 10mg 0.98 10g ShenZhen H&D Pharmaceutical Technology Co., LTD
(3E)-4-(4-Methoxyphenyl)-3-buten-2-one 4-Methoxystyrylmethyl ketone Methoxybenzalacetone p-Anisylideneacetone 4-(4-methoxyphenyl)-3-buten-2-one (en) 4-Methoxybenzalacetone 4'-Methoxybenzylideneacetone 4-Methoxybenzylideneacetone anisylideneacetone 4-(P-METHOXYPHENYL)-3-BUTEN-2-ONE 4-(4-METHOXYPHENYL)-3-BUTEN-2-ONE 4-(4-METHOXY-PHENYL)-BUT-3-EN-2-ONE 1(4-Methoxyphenyl)-but-1-en-3-on 1-(4-Methoxyphenyl)-but-1-en-3-one 3-Buten-2-one, 4-(p-methoxyphenyl)- 4-(4-methoxyphenyl)-3-buten-2-on ANISALACETONE 3-Buten-2-one, 4-(4-methoxyphenyl)- AI3-00222 4-(P-METHOXYPHENYL)-3-BUTEN-2-ONE 98% Ani-sylideneacetone Methyl p-methoxystyryl ketone methyl-p-methoxycinnamylketone methylp-methoxystyrylketone p-Anisalacetone p-Anisilidenacetone p-Methoxybenzalacetone p-Methoxybenzylideneacetone p-methoxystyrylmethylketone 1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE 4-(p-Methoxyphenyl)-3-butene-2-one@1000 μg/mL in AcCN NSC31752 NSC-31752 NSC 31752 Dobutamine Impurity 25 Chlorobutanol Impurity?5 (S 421) 943-88-4 CH3OC6H4CHCHCOCH3