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KN93 hydrochloride

KN93 hydrochloride structure

CAS No.: 1956426-56-4

Chemical Name:: KN93 hydrochloride

Synonyms: CS-1449;KN-93 HCl;KN-93-HCI;KN-93 HCI;KN93 (HCI);KN-93 (HCI);KN93 hydrochloride;KN 93 hydrochloride;KN-93 (hydrochloride)

CBNumber:: CB12666647

Molecular Formula:: C26H30Cl2N2O4S

Molecular Weight:: 537.5

MDL Number:: MFCD27992054

MOL File:: 1956426-56-4.mol

Last updated:2023-06-08 09:02:12

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KN93 hydrochloride Properties

storage temp.	Store at -20°C
solubility	DMF:10.0(Max Conc. mg/mL);18.6(Max Conc. mM) DMSO:20.5(Max Conc. mg/mL);38.14(Max Conc. mM) Water:0.45(Max Conc. mg/mL);0.84(Max Conc. mM)
form	A crystalline solid

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

NFPA 704

	0
2		0

KN93 hydrochloride price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	13864	KN-93 (hydrochloride) ≥98%	1956426-56-4	1mg	$107	2024-03-01	Buy
Cayman Chemical	13864	KN-93 (hydrochloride) ≥98%	1956426-56-4	5mg	$471	2024-03-01	Buy
Cayman Chemical	13864	KN-93 (hydrochloride) ≥98%	1956426-56-4	10mg	$836	2024-03-01	Buy
Biorbyt Ltd	orb611908	KN-93 HCl >98%	1956426-56-4	100mg	$646	2021-12-16	Buy
ChemScene	CS-1561	KN-93hydrochloride 99.43%	1956426-56-4	50mg	$720	2021-12-16	Buy

Product number	Packaging	Price	Buy
13864	1mg	$107	Buy
13864	5mg	$471	Buy
13864	10mg	$836	Buy
orb611908	100mg	$646	Buy
CS-1561	50mg	$720	Buy

KN93 hydrochloride Chemical Properties,Uses,Production

Biological Activity

KN93 hydrochloride is a cell-permeable, reversible and competitive inhibitor of calmodulin-dependent kinase type II (CaMKII) with Ki of 370 nM.

in vitro

After 2 days of KN-93 treatment, 95% of cells are arrested in G1. G1 arrest is reversible; 1 day after KN93 release, a peak of cells had progressed into S and G2-M. KN93 also blocks cell growth stimulated by basic fibroblast growth factor, platelet-derived growth factor-BB, and epidermal growth factor in NIH 3T3 fibroblasts.

target

Ki: 370 nM (CaMK-II)

KN93 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

KN93 hydrochloride Suppliers

Global( 56)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4664	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7553	61
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4863	58
Shanghai JiYi Biotechnology Co. Ltd.	13621943973	sales@shjiyipharmatech.com	China	1166	55

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Career Henan Chemica Co	58
InvivoChem	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aladdin Scientific	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
Amadis Chemical Company Limited	58
Haoyuan Chemexpress Co., Ltd.	61
MedChemexpress LLC	58
Shanghai JiYi Biotechnology Co. Ltd.	55

KN 93 hydrochloride KN-93 (hydrochloride) KN93 hydrochloride KN-93 HCl CS-1449 KN93 (HCI) KN-93 (HCI) KN-93 HCI KN-93-HCI 1956426-56-4 C26H30Cl2N2O4S