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ML335

CAS No.
1069498-96-9
Chemical Name:
ML335
Synonyms
ML335;CYM51010;CID23723457;ML 335,ML335;CYM51010(ML335);Ethyl 1-(4-acetamidobenzyl)-4- phenethylpiperidine-4-carboxylate;1-[[4-(Acetylamino)phenyl]methyl]-4-(2-phenylethyl)-4-Piperidinecarboxylic acid ethyl ester;4-Piperidinecarboxylic acid, 1-[[4-(acetylamino)phenyl]methyl]-4-(2-phenylethyl)-, ethyl ester
CBNumber:
CB12750520
Molecular Formula:
C25H32N2O3
Molecular Weight:
408.53
MDL Number:
MFCD12985402
MOL File:
1069498-96-9.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:15

ML335 Properties

storage temp. 2-8°C
solubility DMSO: soluble10mg/mL, clear
form powder
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
NFPA 704
0
2 0

ML335 price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0980 CYM51010 ≥98% (HPLC) 1069498-96-9 5mg $119 2024-03-01 Buy
Sigma-Aldrich SML0980 CYM51010 ≥98% (HPLC) 1069498-96-9 25mg $594 2024-03-01 Buy
Cayman Chemical 15196 ML-335 ≥98% 1069498-96-9 1mg $44 2024-03-01 Buy
Cayman Chemical 15196 ML-335 ≥98% 1069498-96-9 5mg $118 2024-03-01 Buy
Cayman Chemical 15196 ML-335 ≥98% 1069498-96-9 10mg $193 2024-03-01 Buy
Product number Packaging Price Buy
SML0980 5mg $119 Buy
SML0980 25mg $594 Buy
15196 1mg $44 Buy
15196 5mg $118 Buy
15196 10mg $193 Buy

ML335 Chemical Properties,Uses,Production

Description

The μ-opioid receptor (OPRM1) is the primary site of action for morphine and other opioids associated with the treatment of pain. The occupancy of δ-opioid receptors (OPRD1) by antagonists has been shown to enhance OPRM1 binding and signaling activity. Because heteromerization of OPRM1 and OPRD1 is thought to be a potential mechanism by which this occurs, compounds are being sought that selectively activate OPRM1-OPRD1 heterodimerization while alleviating the unwanted effects associated with prolonged opiate use. ML-335 is the first identified agonist for OPRM1-OPRD1 heterodimerization (EC50 = 403 nM) that demonstrates selectivity over the individual OPRM1 and OPRD1 receptors and the serotonin HT5A receptor (EC50s = 14.9, 1.1, and >40 μM, respectively).

Uses

ML-335 is an agonist for μ-opioid receptor (OPRM1)- δ-opioid receptors (OPRD1) heterodimerization.

Uses

ML335, is a selective activator of both TREK-1 and TREK-2.

ML335 Preparation Products And Raw materials

Raw materials

Preparation Products

ML335 Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139 orders@jknbiochem.com China 4664 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4182 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2989 58
1-[[4-(Acetylamino)phenyl]methyl]-4-(2-phenylethyl)-4-Piperidinecarboxylic acid ethyl ester CID23723457 CYM51010 ML335 4-Piperidinecarboxylic acid, 1-[[4-(acetylamino)phenyl]methyl]-4-(2-phenylethyl)-, ethyl ester CYM51010(ML335) Ethyl 1-(4-acetamidobenzyl)-4- phenethylpiperidine-4-carboxylate ML 335,ML335 1069498-96-9