PYRROLNITRIN
- CAS No.
- 1018-71-9
- Chemical Name:
- PYRROLNITRIN
- Synonyms
- 52230;A-10338;pyroace;nsc-107654;pyrollnitrin;Pyrrolnitrine;Antibiotic A-10338;3-chloro-4-(3-chloro-2-nitrophenyl)-pyrrol;PYRROLE,3-CHLORO-4-(3-CHLORO-2-NITROPHENYL)-;3-chloro-4-(2’-nitro-3’-chlorophenyl)pyrrole
- CBNumber:
- CB1498369
- Molecular Formula:
- C10H6Cl2N2O2
- Molecular Weight:
- 257.07
- MDL Number:
- MFCD00865605
- MOL File:
- 1018-71-9.mol
- MSDS File:
- SDS
| Melting point | 124.5° |
|---|---|
| Boiling point | 410.5±45.0 °C(Predicted) |
| Density | 1.5834 (rough estimate) |
| refractive index | 1.6100 (estimate) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 10 mM |
| form | A solid |
| pka | 14.28±0.50(Predicted) |
| FDA UNII | N0P24B6EDQ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Toxicity | LD50 in rats, rabbits (mg/kg): 68, 105 i.p. (Nishida) | |||||||||
| NFPA 704 |
|
PYRROLNITRIN price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P8861 | Pyrrolnitrin from Pseudomonas cepacia ≥98% (HPLC), solid | 1018-71-9 | 1MG | $385 | 2023-06-20 | Buy |
| American Custom Chemicals Corporation | API0008411 | PYRROLNITRIN 95.00% | 1018-71-9 | 1MG | $994.68 | 2021-12-16 | Buy |
PYRROLNITRIN Chemical Properties,Uses,Production
Description
Pyrrolnitrin, isolated from Pseudomonas species, is highly active against fungi, particularly trichophyte species.
Uses
Antifungal.
Uses
Pyrrolnitrin from Pseudomonas cepacia has been used as a standard in the detection of pyrrolnitrin in Serratia marcescens cell culture extract.
Definition
ChEBI: A member of the class of pyrroles carrying chloro and 3-chloro-2-nitrophenyl substituents at positions 3 and 4 respectively.
Origin
Pyrrolnitrin was found in the cells of Pseudomonas pyrrocinia grownin a medium containing a high concentration of inorganic phosphate.It was discovered by Arima of the University of Tokyo in collaboration with Fujisawa Pharmaceutical Industries Co. in 1965.
Biological Activity
Pyrrolnitrin shows strong activity against a variety of fungi and weak activity against grampositive bacteria.
Biochem/physiol Actions
Pyrrolnitrin blocks the terminal electron transport between succinate or reduced NADH and coenzyme Q. In mitochondria preparations of S. cerevisiae, the antibiotic inhibited succinate oxidase, NADH oxidase, succinate cythochrome C reductase, and NADH-cytochrome C reductase. Pyrrolnitrin is involved in many cellular processes such as oxidative stress, electron transport, DNA and RNA synthesis.
PYRROLNITRIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18219 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21688 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9634 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9923 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
View Lastest Price from PYRROLNITRIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-29 | PYRROLNITRIN
1018-71-9
|
US $8.00-1.00 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- PYRROLNITRIN
1018-71-9
- US $8.00-1.00 / kg
- 99%
- Henan Fengda Chemical Co., Ltd