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ChemicalBook >> CAS DataBase List >>H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2

H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2

H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Structure
H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 structure
CAS No.
111857-96-6
Chemical Name:
H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
Synonyms
BIM 23042;BIM 23042 TFA;(D-2-Nal5,Cys6;BIM-23042, DC-13-217;H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2;(D-2-NAL5,CYS6·11,TYR7,D-TRP8,VAL10,2-NAL12)-SOMATOSTATIN;(D-2-NAL5,CYS6'11,TYR7,D-TRP8,VAL10,2-NAL12)-SOMATOSTATIN-14 (5-12) AMIDE;(D-2-Nal?,Cys?·??,Tyr?,D-Trp?,Val??,2-Nal??)-Somatostatin-14 (5-12) amide trifluoroacetate salt;L-Alaninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-3-(2-naphthalenyl)-, cyclic (2→7)-disulfide
CBNumber:
CB2221348
Molecular Formula:
C63H73N11O9S2
Molecular Weight:
1192.45
MDL Number:
MFCD00237258
MOL File:
111857-96-6.mol
Last updated:2023-05-18 11:31:02
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H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Properties

Boiling point 1554.2±65.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
storage temp. -15°C
solubility Soluble to 1 mg/ml in 0.1% acetic acid
pka 9.90±0.15(Predicted)
form solid
color White

H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 254761 BIM 23042 111857-96-6 1mg $389 2021-12-16 Buy
American Custom Chemicals Corporation PEP0004454 BIM-23042 95.00% 111857-96-6 5MG $496.93 2021-12-16 Buy
ApexBio Technology B5401 BIM23042 111857-96-6 1mg $219 2021-12-16 Buy
Product number Packaging Price Buy
254761 1mg $389 Buy
PEP0004454 5MG $496.93 Buy
B5401 1mg $219 Buy

H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Chemical Properties,Uses,Production

Biological Activity

ki: 49 ±14 nm for neuromedin b-induced endpoint in hunmbr cellsneuromedin b, a mammalian peptide of the bombesinlike peptide family sharing amino acid homology with its amphibian counterpart ranatensin, elicits a diverse array of biological responses in central and peripheral tissues. bim 23042 [d-nal-cys-tyr- d-trp-lys-val-cys-nal-nh2] is a selective neuromedin b antagonist.

in vitro

bim 23042 has a l00-fold greater affinity for bb1 receptors than bb2 receptors. the submaximal mobilisation observed with neuromedin b (1 nm) was abolished by bim 23042 but restored with a subsequently higher concentration of neuromedin b (1 μm). bim 23042 competitively inhibited neuromedin b-induced endpoint in hunmbr cells with a ki of 49 ±14 nm [1].

References

[1] ryan rr, taylor je, daniel jl, cowan a. pharmacological profiles of two bombesin analogues in cells transfected with human neuromedin b receptors. eur j pharmacol. 1996 jun 13;306(1-3):307-14.

H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15956 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10247 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9425 58
Nanjing TGpeptide 		+86-13347807150 +86-13347807150 support@tgpeptide.com China 3279 58
Zhejiang Hangyu API Co., Ltd 		+8617531972939 anna@api-made.com China 2944 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-021-64543801 13764082696 2355241799@qq.com China 42982 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15421 60
Supplier Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Henan Aochuang Chemical Co.,Ltd. 		58
Nanjing TGpeptide 		58
Zhejiang Hangyu API Co., Ltd 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
GL Biochem (Shanghai) Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky (shanghai) International Co.,Ltd 60

View Lastest Price from H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 pictures 2022-10-12 H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
111857-96-6
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

111857-96-6(H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2)Related Search:

H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 1-NAPHTHALEN-2-YL-ETHYLAMINE 3-(NAPHTHALEN-2-YL)PROPAN-1-AMINE 2-NAPHTHALEN-2-YL-ETHYLAMINE (S)-(-)-1-(2-Naphthyl)ethylamine
H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 (D-2-NAL5,CYS6'11,TYR7,D-TRP8,VAL10,2-NAL12)-SOMATOSTATIN-14 (5-12) AMIDE (D-2-Nal5,Cys6 BIM-23042, DC-13-217 BIM 23042 L-Alaninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-3-(2-naphthalenyl)-, cyclic (2→7)-disulfide (D-2-NAL5,CYS6·11,TYR7,D-TRP8,VAL10,2-NAL12)-SOMATOSTATIN (D-2-Nal?,Cys?·??,Tyr?,D-Trp?,Val??,2-Nal??)-Somatostatin-14 (5-12) amide trifluoroacetate salt BIM 23042 TFA 111857-96-6 C63H73N11O9S2 C62H73N11O9S2