D-(-)-Salicin
- CAS No.
- 138-52-3
- Chemical Name:
- D-(-)-Salicin
- Synonyms
- SALICIN;D-SALICIN;SALICOSIDE;WHITE WILLOW;Salicine;Salicylin;Salicin-RM;SALICIN(RG);SALICIN(SH);Salicin >
- CBNumber:
- CB2349192
- Molecular Formula:
- C13H18O7
- Molecular Weight:
- 286.28
- MDL Number:
- MFCD00006590
- MOL File:
- 138-52-3.mol
- MSDS File:
- SDS
Melting point | 196-202 °C |
---|---|
Boiling point | 388.65°C (rough estimate) |
alpha | -61.5 º (c=5, water) |
Density | 1.4340 |
refractive index | -62 ° (C=3, H2O) |
storage temp. | 2-8°C |
solubility | 36g/l |
form | Fine Crystalline Powder |
pka | 12.80±0.70(Predicted) |
color | White |
Water Solubility | 36 g/L (15 ºC), 250 g/L (60 ºC) |
Merck | 14,8324 |
BRN | 89593 |
Stability | Stable, but light sensitive. Incompatible with strong oxidizing agents. |
InChIKey | NGFMICBWJRZIBI-MICYEWLZSA-N |
LogP | -1.232 (est) |
CAS DataBase Reference | 138-52-3(CAS DataBase Reference) |
FDA UNII | 4649620TBZ |
NIST Chemistry Reference | Salicin(138-52-3) |
EPA Substance Registry System | .beta.-D-Glucopyranoside, 2-(hydroxymethyl)phenyl (138-52-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H317 | |||||||||
Precautionary statements | P280-P302+P352 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 43 | |||||||||
Safety Statements | 36/37-37-24/25-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | LZ5901700 | |||||||||
F | 3-10 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29389090 | |||||||||
NFPA 704 |
|
D-(-)-Salicin price More Price(69)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | S0625 | D-(?)-Salicin ≥99% (GC) | 138-52-3 | 5g | $57.1 | 2024-03-01 | Buy |
Sigma-Aldrich | 79588 | D-(?)-Salicin analytical standard | 138-52-3 | 100mg | $230 | 2024-03-01 | Buy |
TCI Chemical | S0003 | Salicin >98.0%(HPLC) | 138-52-3 | 5g | $34 | 2024-03-01 | Buy |
TCI Chemical | S0003 | Salicin >98.0%(HPLC) | 138-52-3 | 25g | $98 | 2024-03-01 | Buy |
Alfa Aesar | A16524 | D-(-)-Salicin, 99% | 138-52-3 | 5g | $40.2 | 2024-03-01 | Buy |
D-(-)-Salicin Chemical Properties,Uses,Production
Description
D(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities, it can inhibit the LPS-induced inflammation in RAW264.7 cells and mouse models.
Chemical Properties
white crystals or powder
Uses
D-(-)-Salicin has been used:
- to study its in vitro anticoagulant and antiplatelet activities
- as a standard in high performance liquid chromatography method (HPLC) for quantitation of salicin from willow plant
- as a tastant in taste threshold assay
- as a constituent of nutrient agar-salicin medium for selective isolation of Lactobacillus paracasei
Uses
Standard substrate in evaluating enzyme Preparations contg b-glucosidase: Weidenhagen, Z. Ver. Zucker-Ind. 79, 591 (1929).
Uses
analgesic, antipyretic
Uses
H1 antihistamine (nonsedating)
Definition
ChEBI: An aryl beta-D-glucoside that is the beta-D-glucoside of the phenolic hydroxy group of salicyl alcohol.
General Description
Salicin is a non-phenolic glucosidic compound extracted from meadowsweet (Filipendula ulmaria L). It is majorly used as a substitute for quinine. Salicin can be used as a therapeutic for patients suffering from rheumatic fever. Salicin acts a metabolic precursor for salicylic acid. It is a novel phytochemical that exhibits immunological cross functions in plants and humans. Salicin facilitates growth and reproduction in plants. In addition, It also protects plants against biotic and abiotic stress.
Biochem/physiol Actions
D-(?)-Salicin exerts anti-rheumatism and anti-inflammatory activities. It inhibits lipopolysaccharide (LPS) induced inflammation in in vitro and in vivo studies. It regulates different signaling pathways such as nuclear factor kappa B (NF-κB) and mitogen-activated protein kinase (MAPK). It also regulates cytokines concentration such as tumor necrosis factor-alpha(TNF-α), interleukin-1β, interleukin-6, and interleukin-10.
Purification Methods
Crystallise D(-)-salicin from EtOAc, EtOH or water and sublime it at 190-195o/12mm. [Armour et al. J Chem Soc 412 1961, IR: Pearl & Darling J Org Chem 24 731 1959, Beilstein 17 III/IV 2986, 17/7 V 113.]
D-(-)-Salicin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
Changsha Staherb Natural Ingredients Co., Ltd. | +86-0731-84213302 +86-18374838656 | info@staherb.cn | China | 1025 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12829 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5986 | 58 |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 346 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18648 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21639 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9220 | 55 |
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32820 | 60 |
Related articles
- D-(-)-Salicin: Phytochemistry, Biosynthesis and Metabolism
- D-(-)-Salicin, a phenolic glycoside, undergoes enzymatic biosynthesis and metabolism into salicylic acid, highlighting its sig....
- Mar 11,2024
- D(-)-Salicin:anti-inflammatory, purgative and analgesic agents
- D(-)-Salicin, an organic compound with the chemical formula C13H18O7, extracted from white willow bark, is a glycoside compoun....
- Sep 15,2023
- Inhibition of D(-)-Salicin
- D(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities, it ....
- Oct 14,2019
View Lastest Price from D-(-)-Salicin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-31 | Salicin
138-52-3
|
US $29.00 / mL | 99.93% | 10g | TargetMol Chemicals Inc. | |||
2024-10-31 | Salicin
138-52-3
|
US $29.00 / mL | 99.93% | 10g | TargetMol Chemicals Inc. | |||
2024-10-31 | D-(-)-Salicin
138-52-3
|
US $0.00-0.00 / KG | 1KG | 98%min | 10tons/month | WUHAN FORTUNA CHEMICAL CO., LTD |
- Salicin
138-52-3
- US $29.00 / mL
- 99.93%
- TargetMol Chemicals Inc.
- Salicin
138-52-3
- US $29.00 / mL
- 99.93%
- TargetMol Chemicals Inc.
- D-(-)-Salicin
138-52-3
- US $0.00-0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
138-52-3(D-(-)-Salicin)Related Search:
1of4