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Norgestrel

CAS No.
6533-00-2
Chemical Name:
Norgestrel
Synonyms
sh850;wy3707;sh70850;monovar;Neogest;Ovrette;fh122-a;NORPLANT;OVRETTE(R);NORGESTREL
CBNumber:
CB2752440
Molecular Formula:
C21H28O2
Molecular Weight:
312.45
MDL Number:
MFCD01546387
MOL File:
6533-00-2.mol
Last updated:2024-10-31 13:32:20

Norgestrel Properties

Melting point 239-241 °C(lit.)
Boiling point 392.36°C (rough estimate)
Density 1.0697 (rough estimate)
refractive index 1.4900 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly, Sonicated), Dichloromethane (Slightly), Methanol (Slightly)
form Solid
pka 13.09±0.40(Predicted)
color Crystals from diethyl ether-hexane
InChIKey WWYNJERNGUHSAO-XUDSTZEESA-N
CAS DataBase Reference 6533-00-2(CAS DataBase Reference)
FDA UNII 3J8Q1747Z2
Proposition 65 List Norgestrel
NCI Drug Dictionary Norplant
EPA Substance Registry System Norgestrel (6533-00-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H315-H319-H360FD
Precautionary statements  P202-P264-P280-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  Xn
Risk Statements  20/21/22-40
Safety Statements  22-36
WGK Germany  3
RTECS  JF8259000
HS Code  2937230000
Toxicity LD50 oral in rat: 5010mg/kg
NFPA 704
0
2 0

Norgestrel price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2487 Norgestrel Pharmaceutical Secondary Standard; Certified Reference Material 6533-00-2 200MG $253 2024-03-01 Buy
Sigma-Aldrich N1250000 Norgestrel European Pharmacopoeia (EP) Reference Standard 6533-00-2 n1250000 $220 2024-03-01 Buy
Sigma-Aldrich 1472000 Norgestrel 6533-00-2 125mg $358 2024-03-01 Buy
Cayman Chemical 10006319 Norgestrel ≥95% 6533-00-2 100mg $25 2024-03-01 Buy
Cayman Chemical 10006319 Norgestrel ≥95% 6533-00-2 500mg $107 2024-03-01 Buy
Product number Packaging Price Buy
PHR2487 200MG $253 Buy
N1250000 n1250000 $220 Buy
1472000 125mg $358 Buy
10006319 100mg $25 Buy
10006319 500mg $107 Buy

Norgestrel Chemical Properties,Uses,Production

Description

Norgestrel is a synthetic progestin and a racemic mixture of dextronorgestrel and levonorgestrel , of which levonorgestrel is the biologically active component. In vivo, norgestrel administered via intrauterine device (IUD) prevents pregnancy in rats. Formulations containing nogestrel have been used as contraceptives.

Chemical Properties

White Solid

Uses

It is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.

Uses

A metabolite of Norgestrel.

Uses

analgesic, antipyretic

Uses

Progestogen; oral contraceptive. The bioactive enantiomer is levorotatory

Uses

An intermediate to the glucuronide metabolite of Levonorgestrel.

Uses

Protected D-(-)-Norgestrel

Uses

A glucuronide metabolite of Levonorgestrel.

Definition

ChEBI: Levonorgestrel is a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid and a terminal acetylenic compound. It has a role as a contraceptive drug, a progestin, a synthetic oral contraceptive and a female contraceptive drug. It is functionally related to a norgestrel. It is an enantiomer of a dexonorgestrel.

brand name

Ovrette (Wyeth).

General Description

Norgestrel, (17α)-(±)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one, and levonorgestrel, (17α)-(-)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one,have a C13 ethyl group instead of the C13 methyl but haveprogestational properties similar to those of norethindrone,with decreased androgenic effects. The ethyl group apparentlyprovides unfavorable steric interactions with the ARthat reduce the affinity compared with that with the PRs.Norgestrel is a racemic mixture, while levonorgestrel is thesingle active levorotatory enantiomer. Norgestrel is usedonly in oral contraceptives. Levonorgestrel is used in bothoral combination birth control products and polymeric implantsthat provide contraception for up to 5 years.

Safety Profile

Human reproductive effects byingestion and implant: menstrual cycle changes ordisorders and female fertility index changes. Anexperimental teratogen. Experimental reproductiveeffects. Questionable carcinogen with experimentalneoplastigenic data. An o

Norgestrel Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 227)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou ICH Biofarm Co., Ltd
+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 998 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 615 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21639 55
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29815 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32024 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10319 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34553 58

View Lastest Price from Norgestrel manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Norgestrel pictures 2024-10-31 Norgestrel
6533-00-2
US $70.00-31.00 / mg 99.91% 10g TargetMol Chemicals Inc.
Norgestrel pictures 2024-10-31 Norgestrel
6533-00-2
US $0.00-0.00 / KG 50g 98%-102%;USP 10KG WUHAN FORTUNA CHEMICAL CO., LTD
Norgestrel pictures 2024-04-17 Norgestrel
6533-00-2
US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
  • Norgestrel pictures
  • Norgestrel
    6533-00-2
  • US $70.00-31.00 / mg
  • 99.91%
  • TargetMol Chemicals Inc.
  • Norgestrel pictures
  • Norgestrel
    6533-00-2
  • US $0.00-0.00 / KG
  • 98%-102%;USP
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Norgestrel pictures
  • Norgestrel
    6533-00-2
  • US $1.10 / g
  • 99.0% min
  • Shaanxi Dideu Medichem Co. Ltd
dl-13b-ethyl-17a-ethynyl-17b-hydroxygon-4-en-3-one 4-GONEN-13BETA-ETHYL-17ALPHA-ETHYNYL-17BETA-OL-3-ONE 4-PREGNEN-13BETA-ETHYL-18,19-DINOR 17BETA-OL-3-ONE-20-YNE 4-ESTREN-17-ALPHA-ETHYNYL-18-HOMO-17-BETA-OL-3-ONE(+/-) D(-)-NORGESTREL D-NORGESTREL (+-)-13-ethyl-17-hydroxy-18,19-dinor-17-alpha-pregn-4-en-20-yn-3-one 13-ethyl-17-hydroxy-19-dinorpregn-4-en-20-yn-3-on(17-alpha)-(+-)-1 monovar sh70850 sh850 wy3707 (17a)-(-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one Neogest Ovrette (+-)-13-Ethyl-17a-ethynyl-17-hydroxygon-4-en-3-one (+-)-17a-Ethynyl-13b-ethylgon-4-en-17b-ol-3-one (+-)-17a-Ethynyl-13-ethyl-17-hydroxygon-4-en-3-one 13-Ethyl-17a-ethynyl-17b-hydroxy-4-gonen-3-one 13-beta-ethyl-17-beta-hydroxy-18,19-dinor-17-alpha-pregn-4-en-20-yn-3-one Norgestrel (DL-) LEVONORGESTRAL Norgestrel Solution, 100ppm Norgestrel IP alpha-norgestrel dl-13-beta-ethyl-17-alpha-ethynyl-17-beta-hydroxygon-4-en-3-one dl-13-beta-ethyl-17-alpha-ethynyl-19-nortestosterone dl-norgestrel fh122-a ldnorgestrel Methylnorethindrone 18,19-Dinor-17a-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (+-)- (8CI) 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17a)-(+-)- (9CI) a-Norgestrel dl-11b-Ethyl-17a-ethynyl-17b-hydroxygon-4-en-3-one 18-Methyl Norgestrel 17-ALPHA-ETHYNYL-18-HOMO-19-NORTESTOSTERONE OVRETTE(R) NORPLANT NORGESTREL NORGESTREL(LEVO) 18,19-Dinor-17-alpha-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (+-) rac-(13R*)-13-Ethyl-17α-hydroxy-18,19-dinorpregna-4-ene-20-yne-3-one Norgestrel (125 mg) 18,19-DINOR-13-BETA-ETHYL-17-BETA-HYDROXY-4-PREGNEN-20-YN-3-ONE 18,19-DINOR-4-PREGNEN-20-YN-3-ONE 13BETA-ETHYL-17ALPHA-ETHYNYL-17BETA-HYDROXYGON-4-EN-3-ONE (+/-)-13-ETHYL-17ALPHA-HYDROXY-18,19-DINORPREGN-4-EN-20-YN-3-ONE (±) Di-Norgestrel (17α)-(+/-)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one Levonorgestrel-D6 Levonorgestrel-d6((-)-Norgestrel-2,2,4,6,6,10-d6) Novogestrel Norgestrel CRS Norgestrel RS Norgestrel USP/EP/BP Norgestrel Steroids Powders (+/-)-NORGESTREL-D6