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ChemicalBook >> CAS DataBase List >>8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Structure
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane structure
CAS No.
423165-13-3
Chemical Name:
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
Synonyms
Maraviroc interMediate(Tropine aMine );-8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl);8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-...;8-benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octane;exo-8-Benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE;8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;(3-exo)-8-Benzyl-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;exo-8-benzyl-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octane;(1R,3s,5S)-8-Benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
CBNumber:
CB41475489
Molecular Formula:
C20H28N4
Molecular Weight:
324.46
MDL Number:
MFCD12911892
MOL File:
423165-13-3.mol
Last updated:2023-11-02 08:54:11
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8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Properties

Melting point 149 ºC
Boiling point 481.5±55.0 °C(Predicted)
Density 1.20
storage temp. 2-8°C
solubility soluble in Chloroform, Dichloromethane
form Solid
pka 9.71±0.40(Predicted)
color Brown
InChI InChI=1/C20H28N4/c1-14(2)20-22-21-15(3)24(20)19-11-17-9-10-18(12-19)23(17)13-16-7-5-4-6-8-16/h4-8,14,17-19H,9-13H2,1-3H3/t17-,18+,19-
InChIKey YHGHRIAZABSSGB-REPLKXPHNA-N
SMILES C1C[C@]2([H])C[C@@H](N3C(C(C)C)=NN=C3C)C[C@@]1([H])N2CC1C=CC=CC=1 |&1:2,5,16,r|
FDA UNII YLC8DY2K99

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS05
Signal word  Danger
Hazard statements  H302-H412-H318
Precautionary statements  P273-P501-P264-P270-P301+P312-P330-P501-P280-P305+P351+P338-P310

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B281420 8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]octane 423165-13-3 10mg $145 2021-12-16 Buy
Biosynth Carbosynth FB55799 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 423165-13-3 500mg $160 2021-12-16 Buy
Biosynth Carbosynth FB55799 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 423165-13-3 1g $240 2021-12-16 Buy
Biosynth Carbosynth FB55799 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 423165-13-3 2g $350 2021-12-16 Buy
American Custom Chemicals Corporation CCH0040425 8-BENZYL-3-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-EXO-8-AZABICYCLO[3.2.1]OCTANE 95.00% 423165-13-3 5MG $495.48 2021-12-16 Buy
Product number Packaging Price Buy
B281420 10mg $145 Buy
FB55799 500mg $160 Buy
FB55799 1g $240 Buy
FB55799 2g $350 Buy
CCH0040425 5MG $495.48 Buy

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Chemical Properties,Uses,Production

Chemical Properties

Brown Solid

Synthesis

A solution of N-(8-benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-isobutyramide in dichloromethane was slowly added to a slurry of phosphorous pentachloride in dichloromethane at 0 °C, and the mixture was allowed to warm to ambient temperature over 2 hours. The resulting solution was cooled to 0°C, and a solution of acetyl hydrazide in amyl alcohol was slowly added at 10 °C. The reaction was stirred at ambient temperature overnight. The mixture was then cooled to 0°C and treated with 2N sodium hydroxide at 20°C, and the pH was adjusted to 9 with 30% aqueous sodium hydroxide. The organic layer was separated and the aqueous layer was extracted with dichloromethane. The combined organic layers were dried and concentrated to about volume. Ethyl acetate and acetic acid were added and the mixture was heated to 80° C for 1 hour, cooled to ambient temperature and stirred overnight. The solution was cooled to 0°C and the pH was adjusted to about 12 with 2N sodium hydroxide. The organic layer was separated and the aqueous layer was extracted with ethyl acetate. The combined organic layers were dried and concentrated to give 8-Benzyl-3-(3-isopropyl-5-methyl-4h-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octane. Yield: 65%.
8-Benzyl-3-(3-isopropyl-5-methyl-4h-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octane

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Preparation Products And Raw materials

Raw materials

Preparation Products

(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane-p-toluenesulfonate

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Suppliers

Global( 58)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Mediking Biopharm Co., Ltd
+undefined15901403431 sales01@mediking.cn China 150 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 6000 58
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9341 55
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81148696 +8615536356810 1047@dideu.com China 2643 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17367 58
Supplier Advantage
Beijing Mediking Biopharm Co., Ltd
58
Hebei Yanxi Chemical Co., Ltd. 		58
Hangzhou FandaChem Co.,Ltd. 		55
Shenzhen Nexconn Pharmatechs Ltd 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
career henan chemical co 		58
Shaanxi Dideu Medichem Co. Ltd 		58
SIMAGCHEM CORP 		58

View Lastest Price from 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE pictures 2023-10-07 8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE
423165-13-3
 US $0.00 / kg 1kg 0.99 20tons Hebei Yanxi Chemical Co., Ltd.
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane pictures 2022-01-18 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
423165-13-3
 US $0.00 / KG 1KG 97.6% 100 tons Honest Joy Holdings Limited
8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE pictures 2020-04-28 8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE
423165-13-3
 US $0.10 / KG 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd

423165-13-3(8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane )Related Search:

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8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 8-Azabicyclo[3,2,1]octane3-[3-methyl-5-(1-methlethyl)-4H-1,2,4-triazol-4-yl]-8-(phenylmethyl) exo-8-Benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 3-[3-Methyl-5-(1-Methylethyl)-4H-1,2,4-triazol-4-yl]-8-(phenylMethyl)-(3-exo)-8-azabicyclo[3.2.1]octane Maraviroc interMediate(Tropine aMine ) 8-Azabicyclo[3.2.1]octane,3-[3-Methyl-5-(1-Methylethyl)-4H-1,2,4-triazol-4-yl]-8-(phenylMethyl)-,(3-exo)- (1R,3s,5S)-8-Benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane -8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl) 8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE exo-8-benzyl-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octane (3-exo)-3-[3-Methyl-5-(1-methylethyl)-4H-1,2,4-triazol- 4-yl] -8-(phenylmethyl)-8-azabicyclo[3.2.1]octane 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-... 8-benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octane (3-exo)-8-Benzyl-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 423165-13-3