ChemicalBook >> CAS DataBase List >>H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH

H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH

H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH structure

CAS No.: 136461-80-8

Chemical Name:: H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH

Synonyms: Osteocalcin(1-49);BGP (1-49) (HUMAN);BONE GLA PROTEIN (HUMAN);OSTEOCALCIN (1-49) (HUMAN);GLA17,21,24-OSTEOCALCIN (HUMAN);BONE GLA PROTEIN (1-49) (HUMAN);OSTEOCALCIN (HUMAN, GLA17,21,24);[GLA17,21,24]-OSTEOCALCIN (1-49);Osteocalcin fragment 1-49 Human >=94% (HPLC), solid;YLYQWLGAPVPYPDPL-GLA-PRR-GLA-VC-GLA-LNPDCDELADHIGFQEAYRRFYGPV

CBNumber:: CB4370884

Molecular Formula:: C269H381N67O82S2

Molecular Weight:: 5929.43

MDL Number:: MFCD00147801

MOL File:: 136461-80-8.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:21

Request For Quotation

H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH Properties

storage temp.	-20°C
solubility	Formic Acid: 1 mg/ml
form	solid
FDA UNII	C5F7I87K3N

SAFETY

Risk and Safety Statements

WGK Germany	3
HS Code	2934999090

H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	O5761	Osteocalcin fragment 1-49 Human ≥94%(HPLC),solid	136461-80-8	500μg	$852	2024-03-01	Buy
Sigma-Aldrich	O5761	Osteocalcin fragment 1-49 Human ≥94% (HPLC), solid	136461-80-8	1mg	$1640	2024-03-01	Buy
Cayman Chemical	24723	Osteocalcin (1-49) (human) (trifluoroacetate salt) ≥95%	136461-80-8	100μg	$459	2024-03-01	Buy
Cayman Chemical	24723	Osteocalcin (1-49) (human) (trifluoroacetate salt) ≥95%	136461-80-8	500μg	$1148	2024-03-01	Buy
Biorbyt Ltd	orb372957	Osteocalcin (1-49) > 95%	136461-80-8	1mg	$1412.7	2021-12-16	Buy

Product number	Packaging	Price	Buy
O5761	500μg	$852	Buy
O5761	1mg	$1640	Buy
24723	100μg	$459	Buy
24723	500μg	$1148	Buy
orb372957	1mg	$1412.7	Buy

H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH Chemical Properties,Uses,Production

Description

Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget''s disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in women. In vitro, osteocalcin induces chemotaxis of MDA-MB-231 breast cancer cells, human peripheral blood monocytes, and rat osteosarcoma cells with osteoblast-like characteristics. It is also expressed by vascular smooth muscle cells (VSMCs) displaying an osteoblast-like phenotype and has been positively associated with calcification of aortic tissue and heart valves in humans.

H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH Suppliers

Global( 69)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10247	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	999	58
Hangzhou Go Top Peptide Biotech	0571-88211921	sales1@gotopbio.com	CHINA	2609	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
Nanjing TGpeptide	+86-13347807150 +86-13347807150	support@tgpeptide.com	China	3279	58
Zhejiang Hangyu API Co., Ltd	+8617531972939	anna@api-made.com	China	2944	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-021-64543801 13764082696	2355241799@qq.com	China	42982	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632	sales@reading-chemicals.com	China	15185	58

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Cellmano Biotech Limited	58
Hangzhou Go Top Peptide Biotech	58
Chengdu Youngshe Chemical Co., Ltd.	58
Nanjing TGpeptide	58
Zhejiang Hangyu API Co., Ltd	58
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58

136461-80-8(H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH)Related Search:

GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLU-PRO-ARG H-PHE-TYR-GLY-PRO-VAL-OH H-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH Osteocalcin (1-43) Osteocalcin 30-43 Fragment

Osteoblast Activating Peptide (mouse, rat) SALCOMINE 2,4-PENTANEDIONE, SILVER DERIVATIVE METHYL ISOCYANOACETATE Tris(2,4-pentanedionato)chroMiuM(III)

Ethyl isocyanoacetate DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) N-BUTYLISOCYANIDE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Tosylmethyl isocyanide

PHENYLSELENOL TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Benzyl isocyanide

1of4

TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL (DISULFIDE BRIDGE: CYS23-CYS29) TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL: YLYQWLGAPVPYPDPL-GLA-PRR-GLA-VC-GLA-LNPDCDELADHIGFQEAYRRFY YLYQWLGAPVPYPDPL-Gla-PRR-Gla-VC-Gla-LNPDCDELADHIGFQEAYRRFYGPV(Gla=γ-CarboxyglutamicAcid:Disulfidebridge:23-29) Tyr-Leu-Tyr-Gln-Trp-Leu-Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-Gla-Pro-Arg-Arg-Gla-Val-Cys-Gla-Leu-Asn-Pro-Asp-Cys-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val(Disu OSTEOCALCIN (HUMAN, GLA17,21,24) OSTEOCALCIN (1-49) (HUMAN) TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL YLYQWLGAPVPYPDPL-GLA-PRR-GLA-VC-GLA-LNPDCDELADHIGFQEAYRRFYGPV H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH [GLA17,21,24]-OSTEOCALCIN (1-49) GLA17,21,24-OSTEOCALCIN (HUMAN) BONE GLA PROTEIN (HUMAN) BONE GLA PROTEIN (1-49) (HUMAN) BGP (1-49) (HUMAN) Osteocalcin(1-49) Osteocalcin fragment 1-49 Human >=94% (HPLC), solid 136461-80-8 C269H381N67O82S2 Intracellular Calcium Signaling BioChemical Calcium-associated Proteins Cell Biology Cell Signaling and Neuroscience peptide Calcium Associated Protein FragmentsPeptides and Proteins Calcium-associated Proteins Proteins for Cell Biology Ion Channel Modulating Peptides Peptides for Cell Biology