ChemicalBook >> CAS DataBase List >>6,7,8-TRIMETHOXYCOUMARIN

6,7,8-TRIMETHOXYCOUMARIN

CAS No.
6035-49-0
Chemical Name:
6,7,8-TRIMETHOXYCOUMARIN
Synonyms
BG8;BG 8;BG-8;DIMETHYLFRAXETIN;Di-O-Methylfraxetin;O,O-DIMETHYLFRAXETIN;DIMETHYLFRAXETIN, O,O-;Dimethylfraxetin, >99%;Fraxetin dimethyl ether;6,7,8-TRIMETHOXYCOUMARIN
CBNumber:
CB5237142
Molecular Formula:
C12H12O5
Molecular Weight:
236.22
MDL Number:
MFCD00145039
MOL File:
6035-49-0.mol
Last updated:2024-10-31 18:15:48

6,7,8-TRIMETHOXYCOUMARIN Properties

Melting point 104-105°C
Boiling point 338.68°C (rough estimate)
Density 1.249
refractive index 1.5140 (estimate)
storage temp. 2-8°C
solubility DMSO : 125 mg/mL (529.17 mM; Need ultrasonic and warming)
form Cryst.
color White to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Risk Statements  22
Safety Statements  22-45
HS Code  29322090
NFPA 704
0
2 0

6,7,8-TRIMETHOXYCOUMARIN price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 300192 Dimethylfraxetin 6035-49-0 20mg $462 2021-12-16 Buy
American Custom Chemicals Corporation PXT0000775 DIMETHYLFRAXETIN 95.00% 6035-49-0 5MG $502.7 2021-12-16 Buy
Biorbyt Ltd orb593888 Di-O-methylfraxetin 6035-49-0 20mg $513.4 2021-12-16 Buy
ChemScene CS-7783 Dimethylfraxetin 99.97% 6035-49-0 25mg $552 2021-12-16 Buy
Biorbyt Ltd orb104580 Dimethylfraxetin >98%,Standard References Grade 6035-49-0 20mg $569.5 2021-12-16 Buy
Product number Packaging Price Buy
300192 20mg $462 Buy
PXT0000775 5MG $502.7 Buy
orb593888 20mg $513.4 Buy
CS-7783 25mg $552 Buy
orb104580 20mg $569.5 Buy

6,7,8-TRIMETHOXYCOUMARIN Chemical Properties,Uses,Production

Chemical Properties

White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Fraxinuschinensis Roxb.

Uses

Dimethylfraxetin has a bactericidal, anti-inflammatory, anti-radiation damage, and immune-enhancing effects.

Definition

ChEBI: 6,7,8-trimethoxy-1-benzopyran-2-one is a member of coumarins.

Biological Activity

Dimethylfraxetin is a Carbonic anhydrase inhibitor with a Ki of 0.0097 μM.

in vitro

At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study .

target

Ki: 0.0097 μM (Carbonic anhydrase)

454-73-9
1099-45-2
6035-49-0
Synthesis of 6,7,8-TRIMETHOXYCOUMARIN from 3-FLUORO-5-NITROBENZOTRIFLUORIDE and Ethyl (triphenylphosphoranylidene)acetate

6,7,8-TRIMETHOXYCOUMARIN Preparation Products And Raw materials

Global( 171)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangsu Yongjian Pharmaceutical Co.,Ltd
+86-0523-80183620 +86-17701422015 982552664@qq.com China 258 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18648 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29886 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953 sales@pioneerbiotech.com China 3000 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58

View Lastest Price from 6,7,8-TRIMETHOXYCOUMARIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dimethylfraxetin pictures 2024-10-31 Dimethylfraxetin
6035-49-0
US $35.00-136.00 / mg ≥95% 10g TargetMol Chemicals Inc.
6,7,8-Trimethoxycoumarin pictures 2023-02-24 6,7,8-Trimethoxycoumarin
6035-49-0
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
6,7,8-TRIMETHOXYCOUMARIN  pictures 2021-10-30 6,7,8-TRIMETHOXYCOUMARIN
6035-49-0
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
O,O-DIMETHYLFRAXETIN 6,7,8-TRIMETHOXYCOUMARIN DIMETHYLFRAXETIN, O,O-(RG) DIMETHYLFRAXETIN DIMETHYLFRAXETIN, O,O- 6,7,8-Trimethoxy-2H-1-benzopyran-2-one Di-O-Methylfraxetin Fraxetin dimethyl ether CouMarin, 6,7,8-triMethoxy- 2H-1-Benzopyran-2-one,6,7,8-triMethoxy Dimethylfraxetin 6,7,8-Trimethoxycoumarin Fraxetin dimethylether (6,7,8-OMe) DIMETHYLFRAXETIN, O,O-(P) 6,7,8-TriMethoxy-2H-chroMen-2-one Dimethylfraxetin, >99% 6,7,8-TRIMETHOXYCOUMARIN ISO 9001:2015 REACH BG 8 BG8 BG-8 6035-49-0 6035-94-0 Coumarins chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract