ChemicalBook >> CAS DataBase List >>Miriplatin
Miriplatin
- CAS No.
- 141977-79-9
- Chemical Name:
- Miriplatin
- Synonyms
- Mibo;Miripla;SM 11355;[(1R,2R)-1,2-Cyclohexanediamine]bis(myristato)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis...;Miriplatin,SM11355,inhibit,Inhibitor,SM 11355,DNA Alkylator/Crosslinker;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum(II)
- CBNumber:
- CB52612602
- Molecular Formula:
- C34H66N2O4Pt
- Molecular Weight:
- 762
- MDL Number:
- MOL File:
- 141977-79-9.mol
Last updated:2023-06-12 13:24:31
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
|---|---|
| solubility | DMF : < 1 mg/mL (insoluble) |
| FDA UNII | 780F0P8N4I |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Miriplatin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2720 | Miriplatin >97.5% (Pt analysis) | 141977-79-9 | 10MG | $75.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2720 | Miriplatin >97.5% (Pt analysis) | 141977-79-9 | 50MG | $306 | 2024-03-01 | Buy |
| ChemScene | CS-3921 | Miriplatin >98.0% | 141977-79-9 | 100mg | $220 | 2021-12-16 | Buy |
| AK Scientific | 3854AH | Miriplatin | 141977-79-9 | 50mg | $236 | 2021-12-16 | Buy |
| ChemScene | CS-3921 | Miriplatin >98.0% | 141977-79-9 | 10mg | $70 | 2021-12-16 | Buy |
Miriplatin Chemical Properties,Uses,Production
Uses
Miplatin is a platinum-based anticancer drug developed by Japan's Sumitomo Pharmaceutical Co., Ltd. It is used in the treatment of liver cancer, malignant lymphoma, non-small cell lung cancer, small cell lung cancer and superficial bladder cancer.
Biological Activity
Miriplatin (SM-11355) is a derivative of cisplatin containing myristate as a carrier ligand. It is a novel lipophilic platinum complex for the treatment of hepatocellular carcinoma.
in vitro
Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.
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in vivo
Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces tumor growth rates the growth of tumor in rats bearing AH109A cells.
Miriplatin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 136)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Jinan Honest Pharm Co., Ltd | +8615318812076 | zpy8217@163.com | China | 286 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8348 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 18958018566; | info@afinechem.com | China | 15377 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9330 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
View Lastest Price from Miriplatin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-11-01 | Miriplatin
141977-79-9
|
US $0.00-0.00 / g | 1g | 90.0% min | 100kgs/month | Hangzhou ICH Biofarm Co., Ltd | |
 |
2021-07-13 | Miriplatin
141977-79-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-09 | Miriplatin
141977-79-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Miriplatin
141977-79-9
- US $0.00-0.00 / g
- 90.0% min
- Hangzhou ICH Biofarm Co., Ltd
-
- Miriplatin
141977-79-9
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Miriplatin
141977-79-9
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
141977-79-9(Miriplatin)Related Search:
[(1R,2R)-1,2-Cyclohexanediamine]bis(myristato)platinum
Miripla
SM 11355
(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum
(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum(II)
(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis...
(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)platinum
Mibo
Miriplatin,SM11355,inhibit,Inhibitor,SM 11355,DNA Alkylator/Crosslinker
141977-79-9
C34H68N2O4Pt