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ChemicalBook >> CAS DataBase List >>N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1)

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1)

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Structure
N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) structure
CAS No.
1374744-69-0
Chemical Name:
N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1)
Synonyms
CL121;TG101348(2ClH.H2O);Fedratinib HCl hydrate;Fedratinib Hydrochloride;Fedratinibdihydrochloride;TG-101348 hydrochloride hydrate;Fedratinib HCl hydrate，TG101348;Fedratinib hydrochloride hydrate;SAR 302503 hydrochloride hydrate;TG-101348 dihydrochloride hydrate
CBNumber:
CB52651162
Molecular Formula:
C27H40Cl2N6O4S
Molecular Weight:
615.6153
MDL Number:
MFCD28137677
MOL File:
1374744-69-0.mol
Last updated:2023-09-20 16:43:00
Request For Quotation

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Properties

solubility DMSO:250.0(Max Conc. mg/mL);409.09(Max Conc. mM)
FDA UNII UH9J2HBQWJ

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0028556 Fedratinibhydrochloridehydrate 99.82% 1374744-69-0 5mg $50 2021-12-16 Buy
ChemScene CS-0028556 Fedratinibhydrochloridehydrate 99.82% 1374744-69-0 10mg $70 2021-12-16 Buy
ChemScene CS-0028556 Fedratinibhydrochloridehydrate 99.82% 1374744-69-0 100mg $150 2021-12-16 Buy
ChemScene CS-0028556 Fedratinibhydrochloridehydrate 99.82% 1374744-69-0 200mg $250 2021-12-16 Buy
ChemScene CS-0028556 Fedratinibhydrochloridehydrate 99.82% 1374744-69-0 500mg $550 2021-12-16 Buy
Product number Packaging Price Buy
CS-0028556 5mg $50 Buy
CS-0028556 10mg $70 Buy
CS-0028556 100mg $150 Buy
CS-0028556 200mg $250 Buy
CS-0028556 500mg $550 Buy

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Chemical Properties,Uses,Production

Uses

A potent, highly selective and ATP-competitive JAK2 inhibitor with an IC50 of 3 nM for JAK2 and JAK2V617F.

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Preparation Products And Raw materials

Raw materials

Preparation Products

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Suppliers

Global( 35)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Beijing Mesochem Technology Co.,Ltd 		+8613651027935 rachel@mesochem.com China 191 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Shanghai Thunder Biological Technology Co., Ltd. 18621609968 1162686636@qq.com China 578 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
Shanghai Hanhong Scientific Co.,Ltd. 021-021-64543801 13764082696 2355241799@qq.com China 42982 64
Jinan Trio PharmaTech Co., Ltd. +86 (531) 88811783 sales@trio-pharmatech.com (International market) China 1856 62
Supplier Advantage
Zhejiang J&C Biological Technology Co.,Limited 		58
InvivoChem 		58
Beijing Mesochem Technology Co.,Ltd 		58
TargetMol Chemicals Inc. 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Amadis Chemical Company Limited 		58
Shanghai Thunder Biological Technology Co., Ltd. 58
Shanghai Boyle Chemical Co., Ltd. 55
Shanghai Hanhong Scientific Co.,Ltd. 64
Jinan Trio PharmaTech Co., Ltd. 62

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) Spectrum

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1)(1374744-69-0)1HNMR
N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate (1:2:1) TG101348(2ClH.H2O) TG-101348 dihydrochloride hydrate CL121 N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide hydrochloride hydrate Fedratinib hydrochloride hydrate N-(tert-Butyl)-3-((5-methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)amino)benzenesulfonamide dihydrochloride hydrate Fedratinib (TG101348) dihydrochloride hydrate SAR 302503 hydrochloride hydrate TG-101348 hydrochloride hydrate Fedratinib Hydrochloride Fedratinib HCl hydrate，TG101348 Fedratinib dihydrochloride monohydrate Fedratinibdihydrochloride STAT5,JAK2V617F,myeloproliferative,TG-101348 hydrochloride,Janus kinase,phosphorylation,anti-proliferation,FLT3,Apoptosis,inhibit,RET,orally,JAK,SAR 302503 hydrochloride,Fedratinib hydrochloride hydrate,anti-cancer,JAK2,Inhibitor,Fedratinib hydrochloride Fedratinib HCl hydrate 1374744-69-0 C27H36N6O3S2HClH2O