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Acetyl Hexapeptide-1

CAS No.
448944-47-6
Chemical Name:
Acetyl Hexapeptide-1
Synonyms
melitane;ACETYL HEXAPEPTIDE-1;melitane/acetylhexapeptide-1;peptides Acetyl Hexapeptide-1;Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH2;Acetyl Hexapeptide-1 (Reference: Melitane);N-Acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophanamide;L-Tryptophanamide, N-acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-;N-Acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophanamide USP/EP/BP;Glp-Gly-Cys-Cys-Asn-Gly-Pro-Lys-Gly-Cys-Ser-Ser-Lys-Trp-Cys-Arg-Asp-His-Ala-Arg-Cys-Cys-NH2(Cys3&Cya15,Cys4&Cys22,Cys10&Cys23)
CBNumber:
CB53052034
Molecular Formula:
C43H59N13O7
Molecular Weight:
870.01
MDL Number:
MOL File:
448944-47-6.mol
Last updated:2024-05-18 08:51:57

Acetyl Hexapeptide-1 Properties

Density 1.39±0.1 g/cm3(Predicted)
pka 13.36±0.46(Predicted)
InChIKey WPIQUSRULDNCKM-IFSWANACSA-N
SMILES C(N)(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1N=CNC=1)NC(=O)[C@H](C)NC(=O)[C@H](CCCC)NC(C)=O

Acetyl Hexapeptide-1 Chemical Properties,Uses,Production

Description

Acetyl hexapeptide-1 is a synthetic peptide composed of the amino acids alanine, arginine, histidine, leucine, phenylalanine and tryptophan. It helps skin better defend itself from environmental aggressors by virtue of a calming effect. This peptide can also help promote a visibly more even skin tone by playing a role in how melanin moves through skin.
Acetyl Hexapeptide-1 is a bit of a special snowflake among peptides as it's not a wrinkle-smoothing, anti-aging active like most of the other ones but it can stimulate pigmentation and melanin production (by interacting with a skin cell receptor called MC1R).
As melanin not only gives the skin its nice tanned color but also works as a natural protection factor, Acetyl Hexapeptide-1, aka Melitane does the same. It not only boosts a natural or an artificial tan but gives extra protection against UV-induced DNA and free radical damage and protects the skin against UV-caused redness.

Definition

Acetyl Hexapeptide-1 is the reaction product of Alanine, arginine, histidine, leucine, phenylalanine and tryptophane hexapeptide with acetic acid. It activates the regulation of melanin synthesis, relating the protection of natural light and inflammatory regulator.

Application

Acetyl Hexapeptide-1 works as a bio-α-MSH peptide analog. It stimulates hair pigmentation, darkens hair and reverses the gray hair process. It also can help repair DNA damage caused by UV exposure and reduce the skin erythema.

benefits

Acetyl Hexapeptide-1has affinity to MC1-R, which is a biomimeticpeptide simulating a-MSH, promote melaninproduction by combining with MC1-R,lt alsopromotes transfer melanin from melanocytes tokeratinocytes, coloring the hair.Its recommended dosage is 0.1~5%.

Mechanism of action

Acetyl Hexapeptide-1 is a novel acetyl hexapeptide, which mainly acts on a presynaptic membrane and a postsynaptic membrane to reduce the transmission of neurotransmitters and reduce the shrinkage of muscles, thereby achieving the purpose of smoothing expression lines and the addition of acetyl hexapeptide-1 to cosmetics does not cause the instability of the cosmetic properties.

Acetyl Hexapeptide-1 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 114)Suppliers
Supplier Tel Email Country ProdList Advantage
Apeloa production Co.,Limited
+86-19131931000 +86-19131931000 admin@apcl.com.cn China 227 58
Shanghai Yunao International Trade Co., Ltd
+8617621705551 asdf@shanghaihg.cn China 265 58
Henan Tengmao Chemical Technology Co. LTD
+8615238638457 salesvip2@hntmhg.com China 415 58
Wuhan Haorong Biotechnology Co.,ltd
+8618565342920 sales@chembj.net China 270 58
zhuzhou dingcheng meihei comestic co.,ltd
+undefined18873369619 dingchengbusiness8@163.com China 242 58
Shanghai Affida new material science and technology center
+undefined15081010295 2691956269@qq.com China 371 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177 sarah@tnjone.com China 1125 58
Shanghai Getian Industrial Co., LTD
+86-15373193816 +86-15373193816 mike@ge-tian.com China 274 58
Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58
Rixing Chemical CO.,LTD
+86-13237129059 -13237129059 sales@rixingchemi.com CHINA 229 55

View Lastest Price from Acetyl Hexapeptide-1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Acetyl Hexapeptide-1 pictures 2024-05-18 Acetyl Hexapeptide-1
448944-47-6
US $26.00-22.00 / box 1box 99% 100000box Shanghai Getian Industrial Co., LTD
Acetyl Hexapeptide-1 pictures 2024-05-17 Acetyl Hexapeptide-1
448944-47-6
US $15.00-10.00 / kg 1kg 99% 1000kg Wuhan Cell Pharmaceutical Co., Ltd
Acetyl Hexapeptide-1 pictures 2024-05-07 Acetyl Hexapeptide-1
448944-47-6
US $0.00-0.00 / kg 1kg 99% 500 Wuhan Haorong Biotechnology Co.,Ltd
N-Acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophanamide melitane ACETYL HEXAPEPTIDE-1 melitane/acetylhexapeptide-1 peptides Acetyl Hexapeptide-1 L-Tryptophanamide, N-acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl- N-Acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophanamide USP/EP/BP Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH2 Glp-Gly-Cys-Cys-Asn-Gly-Pro-Lys-Gly-Cys-Ser-Ser-Lys-Trp-Cys-Arg-Asp-His-Ala-Arg-Cys-Cys-NH2(Cys3&Cya15,Cys4&Cys22,Cys10&Cys23) Acetyl Hexapeptide-1 (Reference: Melitane) 448944-47-6 C43H59N13O7