ChemicalBook >> CAS DataBase List >>ML335
ML335
- CAS No.
- 825658-06-8
- Chemical Name:
- ML335
- Synonyms
- TREK-1/2 Activator;ML335; ML-335; ML 335; TREK-1/2 ACTIVATOR;Potassium Channel,ML-335,ML 335,ML335,KcsA,Inhibitor,inhibit;Benzamide, N-[(2,4-dichlorophenyl)methyl]-4-[(methylsulfonyl)amino]-
- CBNumber:
- CB53373069
- Molecular Formula:
- C15H14Cl2N2O3S
- Molecular Weight:
- 373.25
- MDL Number:
- MFCD06003481
- MOL File:
- 825658-06-8.mol
Last updated:2023-06-30 15:45:59
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H315-H335 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| NFPA 704 |
|
ML335 price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 27635 | ML335 | 825658-06-8 | 5mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 27635 | ML335 | 825658-06-8 | 10mg | $115 | 2024-03-01 | Buy |
| Cayman Chemical | 27635 | ML335 | 825658-06-8 | 25mg | $254 | 2024-03-01 | Buy |
| Cayman Chemical | 27635 | ML335 | 825658-06-8 | 50mg | $477 | 2024-03-01 | Buy |
| TRC | M425225 | ML335 | 825658-06-8 | 5mg | $185 | 2021-12-16 | Buy |
ML335 Chemical Properties,Uses,Production
Description
Two-pore domain potassium (K2P) channels of the TREK subfamily regulate neuronal excitability, influence pain, temperature perception and responses to anesthetics. ML-335 (825658-06-8) is a novel, selective TREK-1,2 activator with EC50s of 14.3 and 5.2 μM.1?It represents an important new pharmacological tool for studying the physiology of TREK channels.
Uses
ML335, is a selective activator of both TREK-1 and TREK-2.
storage
Store at +4°C
References
1) Lolicato?et al.?(2017),?K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site; Nature,?547?364
ML335 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 35)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4182 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9824 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29796 | 68 |
| Medi-tech Bioscientific Co., Ltd. | 0519-83246372 13585352506 | China | 1844 | 58 |
825658-06-8(ML335)Related Search:
ML335; ML-335; ML 335; TREK-1/2 ACTIVATOR
TREK-1/2 Activator
Benzamide, N-[(2,4-dichlorophenyl)methyl]-4-[(methylsulfonyl)amino]-
Potassium Channel,ML-335,ML 335,ML335,KcsA,Inhibitor,inhibit
825658-06-8