TUFTSIN
- CAS No.
- 9063-57-4
- Chemical Name:
- TUFTSIN
- Synonyms
- Taftsin;TUFTSIN;Tuftsin(3TFA);THR-LYS-PRO-ARG;TUFTSIN 2ACOH 4H2O;H-Thr-Lys-Pro-Arg-OH;THR-LYS-PRO-ARG 2ACOH 4H2O;L-Thr-L-Lys-L-Pro-L-Arg-OH;Tuftsin hydrate acetate salt;Tuftsin Tuftsin acetate salt hydrate
- CBNumber:
- CB5769625
- Molecular Formula:
- C21H40N8O6
- Molecular Weight:
- 500.59
- MDL Number:
- MFCD00076891
- MOL File:
- 9063-57-4.mol
- MSDS File:
- SDS
| Density | 1.48±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | −20°C |
| pka | 3.60±0.21(Predicted) |
| Water Solubility | Water : ≥ 160 mg/mL (319.62 mM) |
| Sequence | H-Thr-Lys-Pro-Arg-OH |
| FDA UNII | QF5336J16C |
TUFTSIN price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-7100 | Tuftsin 98.40% | 9063-57-4 | 5mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-7100 | Tuftsin 98.40% | 9063-57-4 | 10mg | $84 | 2021-12-16 | Buy |
| ChemScene | CS-7100 | Tuftsin 98.40% | 9063-57-4 | 25mg | $114 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0003512 | TUFTSIN 95.00% | 9063-57-4 | 5MG | $570 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0003512 | TUFTSIN 95.00% | 9063-57-4 | 10MG | $689 | 2021-12-16 | Buy |
TUFTSIN Chemical Properties,Uses,Production
Uses
Tuftsin is an immunostimulatory agent that induces bactericidal and tumoricidal activity by promoting phagocytosis, antigen presentation and cell migration.
Biological Activity
Tuftsin is a tetrapeptide and a macrophage/microglia activator.
in vitro
Tuftsin is a tetrapeptide, Thr-Lys-Pro-Arg, which resides in the Fc-domain of the heavy chain of immunoglobulin G. Tuftsin possesses a broad spectrum of activities related primarily to the immune system function and exerts on phagocytic cells, notably on macrophages. Tuftsin's capacity to augment cellular activation is mediated by specific receptors that are identified, characterized, and recently isolated from rabbit peritoneal granulocytes. Tuftsin, a macrophage/microglial activator, dramatically improves the clinical course of experimental autoimmune encephalomyelitis (EAE), a well-established animal model for MS. Tuftsin administration correlates with upregulation of the immunosuppressive Helper-2 Tcell (Th2) cytokine transcription factor GATA-3. Tuftsin promotes phagocytic activity for cells of monocytic origin, such as neutrophils, macrophages and microglia, all of which are thought to express Tuftsin receptors.
target
| Human Endogenous Metabolite < span> |
TUFTSIN Preparation Products And Raw materials
Raw materials
Preparation Products
TUFTSIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10247 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3582 | 58 |
| Nanjing TGpeptide | +86-13347807150 +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
