N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
- CAS No.
- 4784-40-1
- Chemical Name:
- N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
- Synonyms
- Ao Suoma hydrochloride;Oxomemazine hydrochloride;Oxomemazine·hydrochloric acid;N,N,β-Trimethyl-[10H]-phenothiazine-10-propanamine 5,5-dioxide hydrochloride;N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride;10-(3-(dimethylamino)-2-methylpropyl)-10H-phenothiazine 5,5-dioxide hydrochloride
- CBNumber:
- CB5925092
- Molecular Formula:
- C18H23ClN2O2S
- Molecular Weight:
- 366.9
- MDL Number:
- MFCD11044395
- MOL File:
- 4784-40-1.mol
- MSDS File:
- SDS
Last updated:2023-05-04 15:15:30
| FDA UNII | 6BOK44G9K6 |
|---|
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H317 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501 |
N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0009065 | METHDILAZINE HYDROCHLORIDE 95.00% | 4784-40-1 | 50MG | $697.34 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009065 | METHDILAZINE HYDROCHLORIDE 95.00% | 4784-40-1 | 500MG | $1758.49 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009065 | METHDILAZINE HYDROCHLORIDE 95.00% | 4784-40-1 | 1G | $2355.15 | 2021-12-16 | Buy |
N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride Chemical Properties,Uses,Production
Originator
Doxergan,Specia,France,1964
Manufacturing Process
Phenothiazine is reacted with 3-dimethylamino-2-methylpropyl chloride in the presence of sodium amide to give 3-(10-phenthiazinyl)-2-methyl-1dimethylaminopropane. 11.9 g of of this intermediate is dissolved with agitation in glacial acetic acid (120 cc). Pure sulfuric acid (d = 1.83; 0.5 cc) is added and a mixture of glacial acetic acid (10 cc) and hydrogen peroxide (8.5 cc of a solution containing 38 g of hydrogen peroxide in 100 cc) is then run in over 20 minutes. The temperature rises from 25°C to 35°C and is then kept at 60°C for 18 hours. The mixture is cooled and water (150 cc) is added and, with cooling, aqueous sodium hydroxide (d = 1.33; 220 cc). The resulting
mixture is extracted with ethyl acetate (3 x 100 cc), the solvent is evaporated on a water bath and the residue is recrystallized from heptane (150 cc). 3(9,9-dioxy-10-phenthiazinyl)-2-methyl-1-dimethylaminopropane (78 g) is obtained, MP 115°C.
The corresponding hydrochloride prepared in ethyl acetate and recrystallized from a mixture of ethanol and isopropanol melts at 250°C.
Therapeutic Function
Antihistaminic
N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride Suppliers
Global( 23)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2255 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9330 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9427 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9798 | 50 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Beijing JHYB Pharmaceutical Technology Co., Ltd | (86)-010-88593845 | China | 29 | 62 | |
| Shanghai ring qi biological technology co., LTD | 13524106587 | sales@hq-chem.com | China | 225 | 58 |
| Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd. | 029-87576359 17691182729 | 1018@dideu.com | China | 1986 | 58 |
| Hefei fuya biotechnology co. LTD | 18096409024 | sales02@foreversyn.com | China | 1953 | 58 |
View Lastest Price from N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-06-15 | N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
4784-40-1
|
US $6780.00 / KG | 1KG | 98% | 1-100kg | Baoji Guokang Bio-Technology Co., Ltd. | |
 |
2021-07-13 | N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
4784-40-1
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-09 | N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
4784-40-1
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
4784-40-1
- US $6780.00 / KG
- 98%
- Baoji Guokang Bio-Technology Co., Ltd.
-
- N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
4784-40-1
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
4784-40-1
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
4784-40-1(N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride)Related Search:
Oxomemazine hydrochloride
Oxomemazine·hydrochloric acid
Ao Suoma hydrochloride
10-(3-(dimethylamino)-2-methylpropyl)-10H-phenothiazine 5,5-dioxide hydrochloride
N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
N,N,β-Trimethyl-[10H]-phenothiazine-10-propanamine 5,5-dioxide hydrochloride
4784-40-1