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tasquinimod

CAS No.
254964-60-8
Chemical Name:
tasquinimod
Synonyms
TASQ);ABR-215050;tasquinimod;Tasquinimod, >98%;Tasquinimod(ABR-215050);7-diMethoxy-4-quinolinyl)oxy]-;ABR-215050; ABR215050; ABR 215050;7-Dimethoxy-quinolin-4-yloxy)-phenylamine;4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]quinoline-3-carboxamide;4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-(4-(trifluoromethyl)-phenyl)-1,2-dihydroquinoline-3-c
CBNumber:
CB61508619
Molecular Formula:
C20H17F3N2O4
Molecular Weight:
406.36
MDL Number:
MFCD18251454
MOL File:
254964-60-8.mol
MSDS File:
SDS
Last updated:2024-10-31 18:15:48

tasquinimod Properties

Boiling point 501.5±50.0 °C(Predicted)
Density 1.427±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility insoluble in H2O; ≥20.32 mg/mL in DMSO; ≥4.75 mg/mL in EtOH with gentle warming and ultrasonic
form solid
pka 4.50±1.00(Predicted)
color White to light yellow
FDA UNII 756U07KN1R
NCI Drug Dictionary tasquinimod

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

tasquinimod price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 17692 Tasquinimod ≥98% 254964-60-8 1mg $49 2024-03-01 Buy
Cayman Chemical 17692 Tasquinimod ≥98% 254964-60-8 5mg $202 2024-03-01 Buy
Cayman Chemical 17692 Tasquinimod ≥98% 254964-60-8 10mg $356 2024-03-01 Buy
Cayman Chemical 17692 Tasquinimod ≥98% 254964-60-8 25mg $593 2024-03-01 Buy
Tocris 7051 Tasquinimod ≥98%(HPLC) 254964-60-8 25 $295 2021-12-16 Buy
Product number Packaging Price Buy
17692 1mg $49 Buy
17692 5mg $202 Buy
17692 10mg $356 Buy
17692 25mg $593 Buy
7051 25 $295 Buy

tasquinimod Chemical Properties,Uses,Production

Description

Tasquinimod is an orally-active quinoline-3-carboxamide derived from roquinimex, an immunomodulatory quinolone with applications in some cancers and autoimmune diseases. Tasquinimod inhibits tumor angiogenesis and supplements radiation or chemotherapy in animal models of prostate cancer. While its precise mechanism of action remains unclear, tasquinimod has been reported to alter signaling through S100A9, thrombospondin-1, HIF-1α, androgen receptor, VEGF, and HDAC3/4.

Uses

Tasquinimod is an orally active antiangiogenic agent which may inhibit HDAC4 signalling. This affects cancer cell survival thus making this compound and anti-cancer agent.

target

tumor microenvironment

storage

Store at -20°C

1354639-61-4
22864-65-9
254964-60-8
Synthesis of tasquinimod from Methyl 4-hydroxy-5-Methoxy-1-Methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate and 4-TRIFLUOROMETHYL-N-METHYLANILINE 97
Global( 108)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32820 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29886 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32024 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com China 52849 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38463 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58

View Lastest Price from tasquinimod manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tasquinimod pictures 2024-10-31 Tasquinimod
254964-60-8
US $99.00-218.00 / mg 99.69% 10g TargetMol Chemicals Inc.
tasquinimod pictures 2019-07-06 tasquinimod
254964-60-8
US $1.00 / KG 1KG 98-100% 1000kg Career Henan Chemical Co
  • Tasquinimod pictures
  • Tasquinimod
    254964-60-8
  • US $99.00-218.00 / mg
  • 99.69%
  • TargetMol Chemicals Inc.
  • tasquinimod pictures
  • tasquinimod
    254964-60-8
  • US $1.00 / KG
  • 98-100%
  • Career Henan Chemical Co

tasquinimod Spectrum

4-Hydroxy-5-methoxy-N-methyl-1-methyl-2-oxo-N-(4-trifluoromethylphenyl)-1,2-dihydroquinoline-3-carboxamide N-Methyl-N-(4-trifluoromethylphenyl)-1,2-dihydro-4-hydroxy-5-methoxy-1-methyl-2-oxoquinoline-3-carboxamide tasquinimod ABR-215050 3-QuinolinecarboxaMide, 1,2-dihydro-4-hydroxy-5-Methoxy-N,1-diMethyl-2-oxo-N-[4-(trifluoroMethyl)phenyl]- 4-Hydroxy-5-Methoxy-1-Methyl-2-oxo-1,2- dihydro-quinoline-3-carboxylic acid Methyl- (4-trifluoroMethyl-phenyl)-aMide 1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-trifluoromethyl)phenyl]-3-quinolinecarboxamide 4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-(4-(trifluoromethyl)-phenyl)-1,2-dihydroquinoline-3-c 4-Hydroxy-N-[4-(trifluoromethyl)phenyl]-5-methoxy-N,1-dimethyl-2-oxo-1,2-dihydroquinoline-3-carboxamide ABR-215050; ABR215050; ABR 215050 Tasquinimod, >98% Tasquinimod(ABR-215050) TASQ) 7-diMethoxy-4-quinolinyl)oxy]- 7-Dimethoxy-quinolin-4-yloxy)-phenylamine 4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-(4-(trifluoromethyl)phenyl)-1,2-dihydroquinoline-3-carboxamide 4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]quinoline-3-carboxamide 254964-60-8 Angiogenesis inhibitor S100 calcium binding protein A9 modulator Inhibitors