ChemicalBook >> CAS DataBase List >>trans-Dichlorodiamineplatinum(II)
trans-Dichlorodiamineplatinum(II)
- CAS No.
- 14913-33-8
- Chemical Name:
- trans-Dichlorodiamineplatinum(II)
- Synonyms
- CPDC;CIS-DDP;PLATINEX;PLATINOL;NEOPLATIN;PLATAMINE;BRIPLATIN;CISPLATYL;CISMAPLAT;nsc131558
- CBNumber:
- CB6236182
- Molecular Formula:
- Cl2H4N2Pt
- Molecular Weight:
- 298.03
- MDL Number:
- MFCD00011623
- MOL File:
- 14913-33-8.mol
- MSDS File:
- SDS
Last updated:2023-05-15 10:42:46
| Melting point | 340 °C (dec.)(lit.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO (Sparingly) |
| form | crystalline |
| color | yellow |
| Water Solubility | Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water. |
| Exposure limits |
ACGIH: TWA 0.002 mg/m3 NIOSH: IDLH 4 mg/m3; TWA 0.002 mg/m3 |
| NCI Dictionary of Cancer Terms | Platinol |
| FDA UNII | BW0OY6ZTD4 |
| EPA Substance Registry System | Platinum, diamminedichloro-, (SP-4-1)- (14913-33-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H317-H318-H334 | |||||||||
| Precautionary statements | P280-P302+P352-P305+P351+P338+P310 | |||||||||
| Hazard Codes | T,Xn | |||||||||
| Risk Statements | 45-25-41-68-42/43-40-23/24/25 | |||||||||
| Safety Statements | 53-26-39-45-36/37-24-23 | |||||||||
| RIDADR | UN 3288 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TP2455000 | |||||||||
| F | 10-21 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 28439000 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,27mg/kg (27mg/kg),Chemico-Biological Interactions. Vol. 5, Pg. 415, 1972. | |||||||||
| NFPA 704 |
|
trans-Dichlorodiamineplatinum(II) price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3252 | Transplatin pharmaceutical secondary standard, certified reference material | 14913-33-8 | 50MG | $576 | 2024-03-01 | Buy |
| Sigma-Aldrich | P1525 | trans-Platinum(II)diammine dichloride | 14913-33-8 | 1g | $323 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP544 | Transplatin British Pharmacopoeia (BP) Reference Standard | 14913-33-8 | 25MG | $266 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1672803 | Transplatin United States Pharmacopeia (USP) Reference Standard | 14913-33-8 | 25mg | $1490 | 2024-03-01 | Buy |
| Alfa Aesar | 010472 | trans-Diamminedichloroplatinum(II), Pt 64.5% min | 14913-33-8 | 1g | $211 | 2024-03-01 | Buy |
trans-Dichlorodiamineplatinum(II) Chemical Properties,Uses,Production
Chemical Properties
Yellow Powder or Crystal
Uses
Transplatin is the trans stereoisomer impurity of trans-Dichlorodiamineplatinum(II), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.
Uses
Transplatin is the trans stereoisomer impurity of Cisplatin (C499500), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.
Definition
ChEBI: A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic.
Safety Profile
Poison by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. See also PLATINUM COMPOUNDS. When heated to decomposition it emits toxic fumes of NOx and Cl-.
trans-Dichlorodiamineplatinum(II) Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 142)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4022 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9126 | 58 |
View Lastest Price from trans-Dichlorodiamineplatinum(II) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-09 | trans-Dichlorodiamineplatinum(II)
14913-33-8
|
US $0.00 / G | 10G | 98%min | 30kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2019-09-02 | trans-Dichlorodiamineplatinum(II)
14913-33-8
|
US $7.00 / KG | 1KG | 99% | 1000kg | Career Henan Chemical Co |
-
- trans-Dichlorodiamineplatinum(II)
14913-33-8
- US $0.00 / G
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- trans-Dichlorodiamineplatinum(II)
14913-33-8
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
14913-33-8(trans-Dichlorodiamineplatinum(II))Related Search:
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CIS-DICHLOROBIS(PYRIDINE)PLATINUM(II)
1of4
TRANS-DICHLORODIAMINEPLATINUM(II)
TRANS-DICHLORODIAMMINE-PLATINUM[II]
NEOPLATIN
PLATINUM DIAMMINO DICHLORIDE
PLATAMINE
PLATINOL
PLATINOXAN
PLATIBLASTIN
PLATINEX
TRANS-DIAMMINEDICHLOROPLATINUM(II), 99.99%
trans-Diamminedichloroplatinum(II), 99.9%
trans-Dichlorodiamineplatinum(II), 99.95%
trans-Dichlorodiammineplatinum(II),99%
TRANS-PLATINUM(II)DIAMINEDICHLORIDE
TRANS-DIAMINECHLOROPLATINUM(II)
TRANS-DIAMINEDICHLOROPLATINUM(II)
trans-Diamminedichloroplatinum(II), Pt 64.5% min
trans-Diamminedichloroplatinum(II), trans-Dichlorodiammineplatinum(II)
Transplatin (25 mg)
trans-Dichlorodiamineplatinum(II)trans-DDPTransplatin
trans-DichlorodiaMineplatinuM(II), 99.95%, (trace Metal basis)
LEDERPLATIN
BRIPLATIN
DIAMMINEDICHLOROPLATINATE (II)
CIS-PLATINUM
CIS-PLATINUM(II)DIAMINE DIHYDROCHLORIDE
CIS-PLATINUM(II)DIAMMINE DICHLORIDE
CISPLATYL
CIS PT(NH3)2CL2
CISMAPLAT
CISPLATIIN
CISPLATIN DIHYDROCHLORIDE
CIS-DIAMMINEPLATINUM(II) DICHLORIDE
CIS-DICHLORODIAMINEPLATINUM(II)
CIS-DICHLORODIAMMINE PLATINUM[II]
CIS-DICHLORODIAMMINOPLATINUM
CIS-DDP
CIS-DIAMMINEPLATINUM (II) CHLORIDE
CIS-DIAMMINEDICHLOROPLATINUM(II)
CIS-DIAMMINEDICHLORPLATINE
CIS-DIAMINEDICHLOROPLATINUM
CIS-DIAMINODICHLOROPLATINUM
CPDC
trans-PlatinuMdiaMMine dichloride (II)
Trans-DiamMinedichloroplatinum(II), Pt Min
transplatin
trans-platinumdiamminedichloride
cisplatin bulk drug impurity A
trans-dichloro-diaminoplatinum (II)
TRANS-PLATINUM(II)DIAMMINE DICHLORIDE
diamminedichloro-platinu(sp-4-1)
dichlorodiamineplatinum(ii)
nsc131558
trans-diaminedichloroplatinum
trans-diamminedichloroplatinum
trans-dichlorodiammineplatinum
TRANS-DIAMMINEDICHLOROPLATINUM(II)
TRANS-DDP