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ALK inhibitor 2

ALK inhibitor 2 structure

CAS No.: 761438-38-4

Chemical Name:: ALK inhibitor 2

Synonyms: ALK inhibitor 2;2-[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-;2-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide;2-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzenesulfonamide;2-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methylbenzenesulfonamide;BenzenesulfonaMide, 2-[[5-chloro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-4-pyriMidinyl]aMino]-N-Methyl-;ALK tyrosine kinase receptor,kinase,Anaplastic lymphoma kinase (ALK),Anaplastic lymphoma kinase,CD246,testis-specific,ALK inhibitor 2,serine/threonine,adhesion,Inhibitor,focal,PTK2 protein tyrosine kinase 2,PTK2,contraception,Cluster of differentiation 246,reversible,ALK inhibitor-2,ALK inhibitor2,inhibit,FAK,Focal adhesion kinase,TSSK2,male

CBNumber:: CB62624075

Molecular Formula:: C23H28ClN7O3S

Molecular Weight:: 518.03

MDL Number:: MFCD23380589

MOL File:: 761438-38-4.mol

Last updated:2023-05-21 10:59:17

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ALK inhibitor 2 Properties

Boiling point	712.4±70.0 °C(Predicted)
Density	1.371±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Powder
pka	11.27±0.10(Predicted)

ALK inhibitor 2 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0796	ALKinhibitor2 99.77%	761438-38-4	5mg	$307	2021-12-16	Buy
ApexBio Technology	A3155	ALKinhibitor2	761438-38-4	5mg	$375	2021-12-16	Buy
ChemScene	CS-0796	ALKinhibitor2 99.77%	761438-38-4	10mg	$430	2021-12-16	Buy
ApexBio Technology	A3155	ALKinhibitor2	761438-38-4	10mg	$524	2021-12-16	Buy
Ambeed	A524942	ALKinhibitor2 98+%	761438-38-4	250mg	$576	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0796	5mg	$307	Buy
A3155	5mg	$375	Buy
CS-0796	10mg	$430	Buy
A3155	10mg	$524	Buy
A524942	250mg	$576	Buy

ALK inhibitor 2 Chemical Properties,Uses,Production

Biological Activity

ALK inhibitor 2 (compound 18) is a potent, pyrimidine ALK inhibitor. It is a potent testis-specific serine/threonine kinase 2 (TSSK2; IC50=37 nM) and focal adhesion kinase (FAK; IC50=5 nM) inhibitor.

in vitro

Testis-specific serine/threonine kinase 2 (TSSK2) is an important target for reversible male contraception. ALK inhibitor 2 (compound 18) contains a methylpiperazine A ring (R1=Me, X=N) and a D ring with R5=methylsulfonamide. ALK inhibitor 2 can undergo metabolic oxidation to form reactive adducts in the presence of glutathione.

target

IC50: 37 nM (TSSK2) and 5 nM (FAK)

ALK inhibitor 2 Preparation Products And Raw materials

Raw materials

Preparation Products

ALK inhibitor 2 Suppliers

Global( 69)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9991	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Career Henan Chemica Co	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
LEAP CHEM CO., LTD.	58
Coresyn Pharmatech Co., Ltd.	58
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

761438-38-4(ALK inhibitor 2)Related Search:

CHLOROMETHYL(DIMETHYL)METHOXYSILANE

ALK inhibitor 2 BenzenesulfonaMide, 2-[[5-chloro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-4-pyriMidinyl]aMino]-N-Methyl- 2-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methylbenzenesulfonamide 2-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzenesulfonamide 2-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide 2-[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl- ALK tyrosine kinase receptor,kinase,Anaplastic lymphoma kinase (ALK),Anaplastic lymphoma kinase,CD246,testis-specific,ALK inhibitor 2,serine/threonine,adhesion,Inhibitor,focal,PTK2 protein tyrosine kinase 2,PTK2,contraception,Cluster of differentiation 246,reversible,ALK inhibitor-2,ALK inhibitor2,inhibit,FAK,Focal adhesion kinase,TSSK2,male 761438-38-4 C23H28ClN7O3S Inhibitors