ChemicalBook >> CAS DataBase List >>AZD2461
AZD2461
- CAS No.
- 1174043-16-3
- Chemical Name:
- AZD2461
- Synonyms
- CS-739;AZD2461;AZD 2461, >=98%;AZD2461 AZD-2461;AZD2461 USP/EP/BP;4-(4-Fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one;4-[4-Fluoro-3-[(4-methoxypiperidin-1-yl)carbonyl]benzyl]phthalazin-1(2H)-one;4-[[4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one;4-[[4-Fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone;1(2H)-Phthalazinone, 4-[[4-fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-
- CBNumber:
- CB62655394
- Molecular Formula:
- C22H22FN3O3
- Molecular Weight:
- 395.43
- MDL Number:
- MFCD24386811
- MOL File:
- 1174043-16-3.mol
Last updated:2023-06-30 15:45:59
| Density | 1.33±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | 2-8°C |
| solubility | insoluble in H2O; ≥16.35 mg/mL in DMSO; ≥45.2 mg/mL in EtOH with ultrasonic |
| pka | 12.07±0.40(Predicted) |
| form | powder |
| color | white to beige |
| FDA UNII | 3K288XF5XJ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H373-H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P260-P314-P501 | |||||||||
| NFPA 704 |
|
AZD2461 price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1858 | AZD2461 ≥98% (HPLC) | 1174043-16-3 | 5MG | $102 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML1858 | AZD2461 ≥98% (HPLC) | 1174043-16-3 | 25MG | $413 | 2023-06-20 | Buy |
| Cayman Chemical | 16876 | AZD 2461 ≥95% | 1174043-16-3 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 16876 | AZD 2461 ≥95% | 1174043-16-3 | 5mg | $183 | 2024-03-01 | Buy |
| Cayman Chemical | 16876 | AZD 2461 ≥95% | 1174043-16-3 | 10mg | $341 | 2024-03-01 | Buy |
AZD2461 Chemical Properties,Uses,Production
Uses
4-[4-Fluoro-3-[(4-methoxypiperidin-1-yl)carbonyl]benzyl]phthalazin-1(2H)-one is a phthalazinone derivative and potential PARP inhibitor.
Biochem/physiol Actions
AZD2461, an olaparib analog, is an orally available, potent and selective PARP1 and PARP2 inhibitor that is a poor substrate for drug transporters. AZD2461 exhibits a high efficacy in olaparib-resistant tumors that overexpress P-glycoprotein.
storage
Store at -20°C
Synthesis of AZD2461 from 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid and 4-Methoxypiperidine hydrochloride
AZD2461 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 108)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 | info@pbpharm.com | CHINA | 498 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27894 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
View Lastest Price from AZD2461 manufacturers
1174043-16-3(AZD2461)Related Search:
AZD2461
4-[4-Fluoro-3-[(4-methoxypiperidin-1-yl)carbonyl]benzyl]phthalazin-1(2H)-one
1(2H)-Phthalazinone, 4-[[4-fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-
AZD 2461, >=98%
4-[[4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one
4-[[4-Fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone
CS-739
AZD2461 USP/EP/BP
4-(4-Fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
AZD2461 AZD-2461
1174043-16-3
Inhibitors
Inhibitor