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Cefodizime

Cefodizime Structure
Cefodizime structure
CAS No.
69739-16-8
Chemical Name:
Cefodizime
Synonyms
FIR-221;Estrofan;Cefodizim;Cefodizme;CEFODIZIME;Cefodizime,CDZM;CefodizMe SodiuM;Sodium cefodizime;CEFODIZIME FREE ACID;Cefodizime USP/EP/BP
CBNumber:
CB6299020
Molecular Formula:
C20H20N6O7S4
Molecular Weight:
584.67
MDL Number:
MFCD00864926
MOL File:
69739-16-8.mol
Last updated:2024-04-28 15:15:04
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Cefodizime Properties

Melting point >170°C (dec.)
alpha D25 -55.9°
Density 1.86±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka pK1 2.85; pK2 3.37; pK3 4.18(at 25℃)
color White to Off-White
CAS DataBase Reference 69739-16-8(CAS DataBase Reference)
FDA UNII Z31298J4HQ
ATC code J01DD09

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38-42/43
Safety Statements  22-26-36/37/39

Cefodizime price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C242865 Cefodizime 69739-16-8 25mg $50 2021-12-16 Buy
TRC C242865 Cefodizime 69739-16-8 1g $120 2021-12-16 Buy
ChemScene CS-0028575 Cefodizime ≥97.0% 69739-16-8 50mg $80 2021-12-16 Buy
ChemScene CS-0028575 Cefodizime ≥97.0% 69739-16-8 100mg $110 2021-12-16 Buy
AK Scientific K170 Cefodizime 69739-16-8 25mg $38 2021-12-16 Buy
Product number Packaging Price Buy
C242865 25mg $50 Buy
C242865 1g $120 Buy
CS-0028575 50mg $80 Buy
CS-0028575 100mg $110 Buy
K170 25mg $38 Buy

Cefodizime Chemical Properties,Uses,Production

Chemical Properties

Cefodizime Sodium is a white to light yellowish white crystalline powder. It has no odor or a slightly peculiar odor and has a bitter taste. It is highly soluble in water (around 270g/L) but only sparingly soluble in ethanol or ether.

Uses

Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity. Cefodizime maybe useful in the treatment of otitis media, sinusitis and gynaecological infections, and for the prophylaxis or treatment of surgical infections.

Definition

ChEBI: Cefodizime is a cephalosporin compound having 5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively. It has a role as an antibacterial drug and an EC 1.14.18.1 (tyrosinase) inhibitor. It is a cephalosporin, a member of 1,3-thiazoles and an oxime O-ether.

Preparation

The synthesis of cefodizime involved the following steps:
Dissolve 6.1g of (2-mercapto-4-methylthiazol-5-yl) acetic acid in water and adjust the pH to 6.5 by adding 2 mol/L sodium hydroxide.
Heat the solution to 70°C and then add a solution of 12g of cefotaxime in 75ml of water with stirring.
Keep stirring the mixture at 70°C for 3 hours while maintaining the pH at 6.5 by adding 2 mol/L sodium hydroxide.
Cool the mixture to room temperature and acidify it to pH 2.8.
Filter the resulting precipitate and wash it with water.
Dry the precipitate under vacuum and in the presence of phosphorus pentoxide.
As a result, 10g of cefodizime is obtained.
Cefodizime, an aminothiazolylcephalosporin. V. Synthesis and structure-activity relationships in the cefodizime series. DOI: 10.7164/antibiotics.40.29

Cefodizime Preparation Products And Raw materials

Raw materials

2-Mercapto-4-methyl-5-thiazoleacetic acid Cefotaxime Ethyl acetate 2-Aminothiazole-4-acetic acid Cyclohexylurea
1-Hydroxybenzotriazole hydrate Dicyclohexylcarbodiimide Formamide

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Preparation Products

T 2588G

Cefodizime Suppliers

Global( 157)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12471 58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		+8617702722807 admin@hbouhuang.com China 3001 58
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
Hebei Guanlang Biotechnology Co., Ltd. 		+86-19930503282 alice@crovellbio.com China 8822 58
Xiamen AmoyChem Co., Ltd 		+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49391 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-519-519-85557386 marketing1@neostarunited.com China 8348 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17367 58
Hebei Runbin Biotechnology Co. LTD 		13180553332 2179877681@qq.com CHINA 996 58
Supplier Advantage
Hebei Mojin Biotechnology Co., Ltd 		58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		58
Shanghai Yingrui Biopharma Co., Ltd. 		60
Hebei Guanlang Biotechnology Co., Ltd. 		58
Xiamen AmoyChem Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
SIMAGCHEM CORP 		58
Hebei Runbin Biotechnology Co. LTD 		58

View Lastest Price from Cefodizime manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cefodizime pictures 2024-04-28 Cefodizime
69739-16-8
 US $5.00 / kg 1kg 99.92% 50000tons Ouhuang Engineering Materials (Hubei) Co., Ltd
Cefodizime pictures 2023-08-15 Cefodizime
69739-16-8
 US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Cefodizime pictures 2022-05-17 Cefodizime
69739-16-8
 US $1.10 / g 1g 99.9% Min 100 Tons Dideu Industries Group Limited
  • Cefodizime pictures
  • Cefodizime
    69739-16-8
  • US $5.00 / kg
  • 99.92%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
  • Cefodizime pictures
  • Cefodizime
    69739-16-8
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
  • Cefodizime pictures
  • Cefodizime
    69739-16-8
  • US $1.10 / g
  • 99.9% Min
  • Dideu Industries Group Limited

69739-16-8(Cefodizime)Related Search:

2-Mercapto-4-methyl-5-thiazoleacetic acid Oxygen Cefodizime sodium Ceftizoxime 4-METHYLTHIAZOLE-2-THIOL
2-Mercapto-4-methyl-1,3-thiazol-5-yl-acetic acid Ceftizoxime sodium Cefetamet hydrochloride Cefodizime 2-MERCAPTO-4-METHYL-5-HYDROXYETHYLTHIAZOLE
2-(2-AMINOTHIAZOL-4-YL)ETHYLAMINE 4-METHYL-5-THIAZOLEACETIC ACID 4,5-DIMETHYL-THIAZOLE-2-THIOL 4-Thiazoleacetamide 2-(2-AMINO-THIAZOL-4-YL)-ACETAMIDE
1,3-THIAZOL-5-YLACETIC ACID Desfuroyl Ceftiofur 2-MERCAPTO_4_METHYI_1,3-THIAZOL-5-YL-ACETIC ACID

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CEFODIZIME Cefodizime,CDZM 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R,7R)- 7-(α-(Z)-Methoxyimino-α-(2-aminothiazol-4-yl)acetamido)-3-((5-carboxymethyl-4-methylthiazol-2-yl)thiomethyl)-3-cephem-4-carboxylic acid 7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid FIR-221 Cefodizme CefodizMe SodiuM Sodium cefodizime Cefodizim 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R,7R)- CEFODIZIME FREE ACID CefodiziMe acid USP/EP/BP Cefodizime USP/EP/BP (6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((5-(carboxymethyl)-4-methylthiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Estrofan 69739-16-8 C20H20N6O7S4 C20H19N6NaO7S4 Pharmaceutical intermediate