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ChemicalBook >> CAS DataBase List >>N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Structure
N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine structure
CAS No.
1438071-12-5
Chemical Name:
N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine
Synonyms
GSK-2945;GSK-2945 (GSK2945 );GSK 2945 DISCONTINUED. Please see G797405;2-Thiophenemethanamine, N-[(4-chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro-;N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine
CBNumber:
CB63464337
Molecular Formula:
C20H18Cl2N2O2S
Molecular Weight:
421.34
MDL Number:
MFCD32204617
MOL File:
1438071-12-5.mol
Last updated:2023-05-15 10:44:01
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N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Properties

Boiling point 525.0±45.0 °C(Predicted)
Density 1.363±0.06 g/cm3(Predicted)
solubility Acetonitrile (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Sonicated)
pka 5.23±0.50(Predicted)
form Solid
color Off-White to Light Beige
Stability Hygroscopic

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Chemical Properties,Uses,Production

Uses

GSK 2945 is an antagonist with high specificity for REV-ERBα, Nuclear heme receptor reverse erythroblastosis virus, which is known to regulate circadian rhythm and more specifically, regulation of cholesterol 7α-hydroxylase (CYP7A1) and bile acid synthesis.

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine synthesis

40137-29-9
104-86-9
1438071-12-5
Synthesis of N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine from 4-CHLORO-2-METHYLBENZALDEHYDE and 4-Chlorobenzylamine

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Preparation Products And Raw materials

Raw materials

4-CHLORO-2-METHYLBENZALDEHYDE 4-Chlorobenzylamine

Preparation Products

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
ShangHai Movin Pharmaceutical Co., Ltd. 13681854265 info@moenpharm.com China 511 55
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 29778 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9180 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
ShangHai Movin Pharmaceutical Co., Ltd. 55
Energy Chemical 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
RD International Technology Co., Limited 58
N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine GSK-2945 GSK-2945 (GSK2945 ) 2-Thiophenemethanamine, N-[(4-chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro- GSK 2945 DISCONTINUED. Please see G797405 1438071-12-5