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2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide

CAS No.
1222-87-3
Chemical Name:
2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide
Synonyms
cbdp;o-Tolyl saligenin phosphate;2-(o-cresyl)-4h-1,3,2-benzodioxaphoran-2-one;2-(2-cresyl)-4h-1-3-2-benzodioxaphosphorin-2-oxide;3,2-benzodioxaphosphorin,2-(o-tolyloxy)-4h-2-oxide;phosphoricacid,cyclicmethylene-o-phenyleneo-tolylester;3,2-benzodioxaphosphorin,2-(2-methylphenoxy)-4h-2-oxide;2-(2-METHYLPHENOXY)-4H-1,3,2-BENZODIOXAPHOSPHORIN 2-OXIDE;2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-Oxide;4H-1,3,2-Benzodioxaphosphorin, 2-(2-methylphenoxy)-, 2-oxide
CBNumber:
CB6765725
Molecular Formula:
C14H13O4P
Molecular Weight:
276.22
MDL Number:
MFCD00798815
MOL File:
1222-87-3.mol
Last updated:2024-05-27 16:27:05

2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide Properties

Boiling point 362.4±42.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)

2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30169 CBDP 55824-13-0 1mg $95 2021-12-16 Buy
Cayman Chemical 30169 CBDP 55824-13-0 5mg $380 2021-12-16 Buy
Product number Packaging Price Buy
30169 1mg $95 Buy
30169 5mg $380 Buy

2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide Chemical Properties,Uses,Production

Uses

Plasma carboxylic-ester hydrolase (EC3.1.1.1) is a very important detoxification route for the toxic stereoisomers of soman. Detoxification is meant in the sense that if soman was bound to carbox-ylic-ester hydrolase, it was not free to inhibit acetylcholinesterase. CBDP (2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide) pretreatment, which inhibited irreversibly carboxylic-ester hydrolase activity without inhibiting phosphoryl phosphatase activity, potentiated the toxicity of soman in mice. In toxicity experiments, CBDP (0.5 mg/kg; iv 1 hr prior to soman) pretreatment potentiated the toxicity of C(±)P(±)-, C(+)P(?)-, and C(?)P(?)-soman to a similar degree[1].

References

[1] John G. Clement. “Stereoisomers of soman (pinacolyl methylphosphonofluoridate): Inhibition of serum carboxylic ester hydrolase and potentiation of their toxicity by CBDP (2-(2-methylphenoxy)-4H-1,3,2-benzodioxaphosphorin-2-oxide) in mice.” Toxicology and applied pharmacology 89 1 (1987): Pages 141-143.

2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 7)Suppliers
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Beijing VSciChem Technology Co., Ltd. 13811761079 vscichem@163.com China 251 64
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 sales@accelachem.com China 11660 64
Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 63720 58
Shaanxi Xihua Chemical Industry Co., Ltd 029-81122149 13992773979 1088@dideu.com China 2730 58

1222-87-3(2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide)Related Search:

2-(2-cresyl)-4h-1-3-2-benzodioxaphosphorin-2-oxide 2-(o-cresyl)-4h-1,3,2-benzodioxaphoran-2-one 3,2-benzodioxaphosphorin,2-(2-methylphenoxy)-4h-2-oxide 3,2-benzodioxaphosphorin,2-(o-tolyloxy)-4h-2-oxide cbdp phosphoricacid,cyclicmethylene-o-phenyleneo-tolylester o-Tolyl saligenin phosphate 2-(2-METHYLPHENOXY)-4H-1,3,2-BENZODIOXAPHOSPHORIN 2-OXIDE 4H-1,3,2-Benzodioxaphosphorin, 2-(2-methylphenoxy)-, 2-oxide 2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-Oxide 1222-87-3 C14H13O4P