ChemicalBook >> CAS DataBase List >>4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoroMethyl)propylidene]aMino]benzenesulfonaMide

4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoroMethyl)propylidene]aMino]benzenesulfonaMide

CAS No.
1061214-09-2
Chemical Name:
4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoroMethyl)propylidene]aMino]benzenesulfonaMide
Synonyms
SLXB-YSW;Celebrex J;Celecoxib-013;Celecoxib USP Impurity F;(Z)-4-((1,1,1-trifluoro-4-oxo;Celecoxib benzylic hydroxy impurity;1061214-09-2;Celecoxib Diketo Schiff's Base II Impurity;Celecoxib Diketo Schiff’s Base II Impurity;Celecoxib Diketo Schiff's Base II Impurityuri
CBNumber:
CB72695308
Molecular Formula:
C17H15F3N2O3S
Molecular Weight:
384.37
MDL Number:
MFCD32069550
MOL File:
1061214-09-2.mol
Last updated:2023-04-23 13:52:06

4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoroMethyl)propylidene]aMino]benzenesulfonaMide Properties

Melting point 178-179°C
Boiling point 492.4±55.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka 10.18±0.10(Predicted)
form Solid
color Yellow
FDA UNII GKR98KJ8J2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoroMethyl)propylidene]aMino]benzenesulfonaMide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M327010 4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]benzenesulfonamide 1061214-09-2 250mg $1390 2021-12-16 Buy
Product number Packaging Price Buy
M327010 250mg $1390 Buy

4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoroMethyl)propylidene]aMino]benzenesulfonaMide Chemical Properties,Uses,Production

Uses

4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]benzenesulfonamide, is an impurity of Celecoxib (C251000), which is a selective cyclooxygenase-2 (COX-2) inhibitor, an anti-inflammatory agent. It is also used in treatment of familial adenomatous polyposis.

4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoroMethyl)propylidene]aMino]benzenesulfonaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoroMethyl)propylidene]aMino]benzenesulfonaMide SLXB-YSW Celecoxib Diketo Schiff's Base II Impurity Celecoxib-013 (Z)-4-((1,1,1-trifluoro-4-oxo Celecoxib Diketo Schiff's Base II Impurityuri Celebrex J Benzenesulfonamide, 4-[[3-(4-methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]- (Z)-4-((1,1,1-trifluoro-4-oxo-4-(p-tolyl)butan-2-ylidene)amino)benzenesulfonamide 1061214-09-2 4-((1,1,1-Trifluoro-4-oxo-4-(p-tolyl)butan-2-ylidene)amino)benzenesulfonamide Celecoxib USP Impurity F Celecoxib benzylic hydroxy impurity Celecoxib Diketo Schiff’s Base II Impurity 1061214-09-2 Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds