ChemicalBook >> CAS DataBase List >>Glatiramer acetate

Glatiramer acetate

CAS No.
147245-92-9
Chemical Name:
Glatiramer acetate
Synonyms
ProtiraMer;GlatiraMer-d7;Glatirameracetat;GaltiraMer acetate;GLATIRAMER ACETATE;Chloramine B 127-52-6;Glatiramer acetate API;Glatiramer acetate USP/EP/BP;Glatiramer acetate [USAN:BAN];Pharmaceutical Glatiramer acetate
CBNumber:
CB7285192
Molecular Formula:
C25H45N5O13
Molecular Weight:
623.66
MDL Number:
MFCD27978717
MOL File:
147245-92-9.mol
MSDS File:
SDS
Last updated:2024-03-16 07:03:48

Glatiramer acetate Properties

Melting point >239°C (dec.)
storage temp. Refrigerator
solubility Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
CAS DataBase Reference 147245-92-9(CAS DataBase Reference)
FDA UNII 5M691HL4BO
ATC code L03AX13

Pharmacokinetic data

Protein binding Large

Glatiramer acetate price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 9000571 Glatiramer (acetate) ≥95% 147245-92-9 1mg $37 2024-03-01 Buy
Cayman Chemical 9000571 Glatiramer (acetate) ≥95% 147245-92-9 5mg $134 2024-03-01 Buy
Cayman Chemical 9000571 Glatiramer (acetate) ≥95% 147245-92-9 10mg $231 2024-03-01 Buy
Cayman Chemical 9000571 Glatiramer (acetate) ≥95% 147245-92-9 25mg $397 2024-03-01 Buy
Usbiological 012799 Glatiramer Acetate 147245-92-9 5mg $276 2021-12-16 Buy
Product number Packaging Price Buy
9000571 1mg $37 Buy
9000571 5mg $134 Buy
9000571 10mg $231 Buy
9000571 25mg $397 Buy
012799 5mg $276 Buy

Glatiramer acetate Chemical Properties,Uses,Production

Originator

Copaxone,Teva Pharmaceuticals,Israel

Uses

Glatiramer Acetate-Dx is labelled Glatiramer Acetate (G406800) which is a random basic synthetic copolymer of L-alanine, L-lysine, l-glutamic acid and L-tyrosine. Glatiramer acetate is an immunomodulator used in treatment of multiple sclerosis.

Uses

Glatiramer acetate is a random basic synthetic copolymer of L-alanine, L-lysine, l-glutamic acid and L-tyrosine in a molar ratio of 6:1.9:4.7:1. Glatiramer acetate is an immunomodulator used in treatment of multiple sclerosis.

Manufacturing Process

Glatiramer Acetate is water soluble copolypeptide with molecular weight 15,000-25,000.
Copolymer is prepared by copolymerization of the N-carboxyanhydrides of tyrosine, alanine, lysine, and glutamic acid. The polymerisation was carried out at ambient temperature in anhydrous dioxane with diethylamine as initiator. Glatiramer Acetate have the ratio alanin:glutamic acid:lysine:tyrosine = 1:6:4.54:2.

brand name

Copaxone (Teva).

Therapeutic Function

Immunomodulator

Clinical Use

Immunomodulating drug:

Treatment for patients at a high risk of developing multiple sclerosis and for reduction in relapses in ambulatory patients

Metabolism

A substantial fraction of a subcutaneous dose of glatiramer is believed to be hydrolysed locally. Some of the injected dose is also presumed to enter the lymphatic system, either intact or partially hydrolysed.

Glatiramer acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 200)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma Audley
+86-18336680971 +86-18126314766 nova@sh-teruiop.com China 525 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
Biochempartner
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Shochem(Shanghai) Co.,Ltd
86-21-50800795 info@shochem.com CHINA 288 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Beijing Yibai Biotechnology Co., Ltd
0086-182-6772-3597 sales04@yibaibiotech.com CHINA 419 58

View Lastest Price from Glatiramer acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Glatiramer acetate pictures 2024-04-26 Glatiramer acetate
147245-92-9
US $10.00-3.00 / g 10g 99% 300tons Hebei Dangtong Import and export Co LTD
Glatiramer acetate pictures 2024-03-16 Glatiramer acetate
147245-92-9
US $35.00-25.00 / kg 1kg 99.8% 200tons/year Sigma Audley
Glatiramer acetate pictures 2023-08-16 Glatiramer acetate
147245-92-9
US $2.00 / KG 1KG >99% 2000T Weijer International Trade (Hebei) Co., Ltd
  • Glatiramer acetate pictures
  • Glatiramer acetate
    147245-92-9
  • US $10.00-3.00 / g
  • 99%
  • Hebei Dangtong Import and export Co LTD
  • Glatiramer acetate pictures
  • Glatiramer acetate
    147245-92-9
  • US $2.00 / KG
  • >99%
  • Weijer International Trade (Hebei) Co., Ltd
ProtiraMer GaltiraMer acetate GlatiraMer-d7 Glatiramer acetate [USAN:BAN] GLATIRAMER ACETATE l-glutamic acid polymer with l-alanine, l-lysine and l-tyrosine, acetate (salt) 511: PN: WO2010103292 PAGE: 64 claiMed sequence L-Alanine polyMer with L-GlutaMic Acid L-Lysine L-Tyrosine Acetate L-GlutaMic Acid peptide with L-Alanine L-Lysine L-Tyrosine Acetate Salt L-Tyrosine polyMer with L-Alanine L-GlutaMic Acid L-Lysine Acetate acetic acid,(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid,(2S)-2-aminopentanedioic acid,(2S)-2-aminopropanoic acid,(2S)-2,6-diaminohexanoic acid Pharmaceutical Glatiramer acetate aceticacid,(2S)-2-amino-3-(4-hydroxyphenyl)propanoicacid,(2S)-2-aminopentanedioicacid,(2S)-2-aminopropanoicacid,(2S)-2,6-diaminohexanoicaci Glatiramer acetate USP/EP/BP Glatirameracetat Glatiramer acetate API Chloramine B 127-52-6 147245-92-9 C25H45N5O13 C9H11NO3C6H14N2O2C5H9NO4C3H7NO2XxC2H4O2 Amino Acids & Derivatives Intermediates & Fine Chemicals Peptides Pharmaceuticals API