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Ningetinib

Ningetinib structure

CAS No.: 1394820-69-9

Chemical Name:: Ningetinib

Synonyms: CS-2653;CT053PTSA;Ningetinib;Ningetinib(free base);Ningetinib-Tosylate(free base);Vascular endothelial growth factor receptor,inhibit,c-Met/HGFR,TAM Receptor,Mer,Tyro3,VEGFR,Ningetinib,Axl,Inhibitor;N-(3-fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide;1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl]oxy]phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-

CBNumber:: CB73367255

Molecular Formula:: C31H29FN4O5

Molecular Weight:: 556.58

MDL Number:: MFCD28502048

MOL File:: 1394820-69-9.mol

Last updated:2023-05-21 10:59:17

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Ningetinib Properties

Density	1.348±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 15 mg/ml; DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml; DMSO: 2 mg/ml
form	A crystalline solid
pka	11.00±0.70(Predicted)
FDA UNII	PW3Q92Z6A4

Ningetinib price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	25233	Ningetinib ≥98%	1394820-69-9	1mg	$48	2024-03-01	Buy
Cayman Chemical	25233	Ningetinib ≥98%	1394820-69-9	5mg	$186	2024-03-01	Buy
Cayman Chemical	25233	Ningetinib ≥98%	1394820-69-9	10mg	$301	2024-03-01	Buy
Cayman Chemical	25233	Ningetinib ≥98%	1394820-69-9	25mg	$521	2024-03-01	Buy
Biosynth Carbosynth	BN168497	Ningetinib	1394820-69-9	50mg	$750	2021-12-16	Buy

Product number	Packaging	Price	Buy
25233	1mg	$48	Buy
25233	5mg	$186	Buy
25233	10mg	$301	Buy
25233	25mg	$521	Buy
BN168497	50mg	$750	Buy

Ningetinib Chemical Properties,Uses,Production

Uses

Ningetinib, is a potent, orally bioavailable small molecule tyrosine kinase inhibitor (TKI) with IC50s of 6.7, 1.9 and <1.0 nM for c-Met, VEGFR2 and Axl, respectively.

Ningetinib Preparation Products And Raw materials

Raw materials

Preparation Products

Ningetinib Suppliers

Global( 38)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
ChemShuttle, Inc.	0510-83588313-802 18800520310;	sales@chemshuttle.com	China	2968	62
Shanghai Topbiochem Technology Co., Ltd	021-58170097	info@topbiochem.com	China	9452	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3423	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4182	55
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2990	58

Supplier	Advantage
InvivoChem	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
ChemShuttle, Inc.	62
Shanghai Topbiochem Technology Co., Ltd	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
Shanghai Lollane Biological Technology Co.,Ltd.	55
Shanghai Rechem science Co., Ltd.	58

CS-2653 Ningetinib-Tosylate(free base) Ningetinib Ningetinib(free base) CT053PTSA 1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl]oxy]phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl- N-(3-fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide Vascular endothelial growth factor receptor,inhibit,c-Met/HGFR,TAM Receptor,Mer,Tyro3,VEGFR,Ningetinib,Axl,Inhibitor 1394820-69-9