ChemicalBook >> CAS DataBase List >>CGP 71683 HYDROCHLORIDE
CGP 71683 HYDROCHLORIDE
- CAS No.
- 192322-50-2
- Chemical Name:
- CGP 71683 HYDROCHLORIDE
- Synonyms
- CGP 71683;CGP71683HCl;CGP-71683A HCl;UNII-45B73P82A3;CGP 71683 HYDROCHLORIDE;CGP 71683A hydrochloride;CGP-71683A; CGP 71683A; CGP71683A; UNII-45B73P82A3;N-[[TRANS-4-[[(4-AMINO-2-QUINAZOLINYL)AMINO]METHYL]CYCLOHEXYL]METHYL]-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;N-rel-(((1r,4r)-4-(((4-Aminoquinazolin-2-yl)amino)methyl)cyclohexyl)methyl)naphthalene-1-sulfonamide hydrochloride;1-Naphthalenesulfonamide, N-[[trans-4-[[(4-amino-2-quinazolinyl)amino]methyl]cyclohexyl]methyl]-, hydrochloride (1:1)
- CBNumber:
- CB8269070
- Molecular Formula:
- C26H30ClN5O2S
- Molecular Weight:
- 512.07
- MDL Number:
- MFCD07783999
- MOL File:
- 192322-50-2.mol
- MSDS File:
- SDS
Last updated:2023-09-04 16:42:00
| storage temp. | Inert atmosphere,2-8°C |
|---|---|
| solubility | H2O: ~14 mg/mL, soluble |
| form | solid |
| color | off-white |
| FDA UNII | 45B73P82A3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
CGP 71683 HYDROCHLORIDE price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28778 | CGP 71683 (hydrochloride) | 192322-50-2 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 28778 | CGP 71683 (hydrochloride) | 192322-50-2 | 10mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 28778 | CGP 71683 (hydrochloride) | 192322-50-2 | 5mg | $145 | 2024-03-01 | Buy |
| Tocris | 2199 | CGP71683hydrochloride ≥99%(HPLC) | 192322-50-2 | 10 | $223 | 2021-12-16 | Buy |
| Tocris | 2199 | CGP71683hydrochloride ≥99%(HPLC) | 192322-50-2 | 50 | $934 | 2021-12-16 | Buy |
CGP 71683 HYDROCHLORIDE Chemical Properties,Uses,Production
Description
CGP 71683 is an antagonist of neuropeptide Y (NPY) receptor Y5 (IC50 = 1.4 nM in a radioligand binding assay). It is selective for Y5 over Y1, Y2, and Y4 receptors (IC50s = 2,765, 7,187, and 5,637 nM, respectively). It inhibits NPY-induced increases in BT-549 cell growth and MDA-MB-231 cell migration when used at a concentration of 0.25 μM. CGP 71683 (10 mg/kg, i.p.) inhibits increases in food intake induced by intracerebroventricular administration of NPY in rats.
Biological Activity
Extremely selective, non-peptide NPY Y 5 receptor antagonist. Displays > 1000-fold selectivity over Y 1 , Y 2 and Y 4 receptors; IC 50 values are 1.4, 2765, 7187 and 5637 nM at cloned rat Y 5 , Y 1 , Y 2 and Y 4 receptors respectively. Potently inhibits NPY-induced food intake following i.p. administration in diabetic, free-feeding and fasted rats.
storage
Store at +4°C
CGP 71683 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 58)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18219 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Guangzhou Zhiya Chemdrugs Co.,Ltd | 18122150900 | sculk28@163.com | China | 646 | 55 |
192322-50-2(CGP 71683 HYDROCHLORIDE)Related Search:
CGP 71683 HYDROCHLORIDE
N-[[TRANS-4-[[(4-AMINO-2-QUINAZOLINYL)AMINO]METHYL]CYCLOHEXYL]METHYL]-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
CGP 71683
CGP71683HCl
1-Naphthalenesulfonamide, N-[[trans-4-[[(4-amino-2-quinazolinyl)amino]methyl]cyclohexyl]methyl]-, hydrochloride (1:1)
UNII-45B73P82A3
CGP-71683A; CGP 71683A; CGP71683A; UNII-45B73P82A3
CGP 71683A hydrochloride
CGP-71683A HCl
N-rel-(((1r,4r)-4-(((4-Aminoquinazolin-2-yl)amino)methyl)cyclohexyl)methyl)naphthalene-1-sulfonamide hydrochloride
NPY receptor,CGP-71683,CGP 71683,Inhibitor,inhibit,CGP71683 hydrochloride,CGP-71683 hydrochloride,CGP71683,Neuropeptide Y Receptor
192322-50-2
C26H30ClN5O2S
Analytical Standards
Analytical Chromatography Product Catalog
Forensic and Veterinary Standards
Chromatography
Drug Standards
Neuropeptide Y (NPY ) receptor