ChemicalBook >> CAS DataBase List >>4-Cyanophenylboronic acid
4-Cyanophenylboronic acid
- CAS No.
- 126747-14-6
- Chemical Name:
- 4-Cyanophenylboronic acid
- Synonyms
- SWF-108;AKOS BRN-0076;CHEMBRDG-BB 3200965;RARECHEM AH PB 0209;4-Boronobenzonitrile;4-Cyanophenylboronic;4-cyanobboronic acid;4-Cyanophenylboric acid;4-Cyanophenylboronicaci;2-Cyanophenylboroic acid
- CBNumber:
- CB8283302
- Molecular Formula:
- C7H6BNO2
- Molecular Weight:
- 146.94
- MDL Number:
- MFCD01318968
- MOL File:
- 126747-14-6.mol
- MSDS File:
- SDS
Last updated:2024-04-08 16:27:35
| Melting point | >350 °C (lit.) |
|---|---|
| Boiling point | 355.9±44.0 °C(Predicted) |
| Density | 1.25±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO, Methanol (Slightly) |
| pka | 7.38±0.10(Predicted) |
| form | Powder |
| color | White to yellow |
| BRN | 6593772 |
| CAS DataBase Reference | 126747-14-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-37/39-26-36 | |||||||||
| RIDADR | UN3439 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
4-Cyanophenylboronic acid price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 521418 | 4-Cyanophenylboronic acid ≥95% | 126747-14-6 | 1g | $40.38 | 2024-03-01 | Buy |
| Sigma-Aldrich | 521418 | 4-Cyanophenylboronic acid ≥95% | 126747-14-6 | 10g | $144.8 | 2024-03-01 | Buy |
| TCI Chemical | C1778 | 4-Cyanophenylboronic Acid (contains varying amounts of Anhydride) | 126747-14-6 | 1g | $19 | 2024-03-01 | Buy |
| TCI Chemical | C1778 | 4-Cyanophenylboronic Acid (contains varying amounts of Anhydride) | 126747-14-6 | 5g | $45 | 2024-03-01 | Buy |
| Alfa Aesar | L18007 | 4-Cyanobenzeneboronic acid, 98% | 126747-14-6 | 1g | $52.65 | 2024-03-01 | Buy |
4-Cyanophenylboronic acid Chemical Properties,Uses,Production
Description
4-Cyanophenylboronic acid can be used for palladium catalyzed Suzuki cross-coupling reactions to synthesize 6-acryl-2,4-diamino-pyrimidines and triazines. It is used as precursor in the synthesis of inhibitors such as Tpl2 kinase inhibitors and P2X7 antagonists used in the treatment of pain. It is also a reagent used for preparation of himbacine analogs as thrombin receptor antagonists and potential antiplatelet agents, trisulfonated calixarene upper-rim sulfonamido and their complexation with trimethyllysine epigenetic mark, antimalarial compounds via Suzuki cross-coupling, and deoxyuridine derivatives.
Reference
- G. Cooke, H. A. de Cremiers, V. M. Rotello, B. Tarbit, P. E. Vandersträten, Synthesis of 6-aryl-2,4-diamino-pyrimidines and triazines using palladium catalysed Suzuki cross-coupling reactions, Tetrahedron, 2001, vol. 57, pp. 2787-2789
- N. Ni, H. Chou, J. Wang, M. Li, C. Lu, P. C. Tai, B. Wang, Identification of boronic acids as antagonists of bacterial quorum sensing in Vibrio harveyi, Biochemical and Biophysical Research Communications, 2008, vol. 369, pp. 590-594
Chemical Properties
white to yellow powder
Uses
Intermediates of Liquid Crystals
Uses
suzuki reaction
Uses
4-Cyanophenylboronic Acid is a reactant used in the synthesis of (AMG-8718), an inhibitor of β-site amyloid precursor protein cleaving enzyme (BACE1).
4-Cyanophenylboronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 477)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1100 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18232 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15957 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Beijing Green Guardee Technology Co., Ltd | 86-010-69706062 | sales2@greenguardee.com | CHINA | 650 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
View Lastest Price from 4-Cyanophenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-08 | 4-Cyanophenylboronic acid
126747-14-6
|
US $34.00-1.20 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-11-30 | 4-Cyanophenylboronic acid
126747-14-6
|
US $0.00-0.00 / kg | 1kg | 99.9% | 30000 Kg | Hebei Xinsheng New Material Technology Co., LTD. | |
 |
2023-10-30 | 4-Cyanophenylboronic acid
126747-14-6
|
US $35.00-25.00 / kg | 1kg | 99% | 20 Ton | Hebei Xinsheng New Material Technology Co., LTD. |
-
- 4-Cyanophenylboronic acid
126747-14-6
- US $34.00-1.20 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4-Cyanophenylboronic acid
126747-14-6
- US $0.00-0.00 / kg
- 99.9%
- Hebei Xinsheng New Material Technology Co., LTD.
-
- 4-Cyanophenylboronic acid
126747-14-6
- US $35.00-25.00 / kg
- 99%
- Hebei Xinsheng New Material Technology Co., LTD.
126747-14-6(4-Cyanophenylboronic acid)Related Search:
4-Aminophenylboronic acid
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Methyl 4-cyanobenzoate
4-Hydroxyphenylboronic acid
3,5-Dimethylphenylboronic acid
Phenylboronic acid
Phenethylboronic acid
5-FLUORO-4-IODO-1H-PYRROLO[2,3-B]PYRIDINE
3,6-Dichloro-4-methylpyridazine
1of4
CHEMBRDG-BB 3200965
4-CYANOPHENYLBORONIC ACID
4-CYANOBENZENEBORONIC ACID
AKOS BRN-0076
RARECHEM AH PB 0209
P-CYANOPHENYLBORONIC ACID
Boronic acid, B-(4-cyanophenyl)-
BORONIC ACID, B-(4-CYANOPHENYL)-;
4-Cyanophenylboric acid
Boronic acid, (4-cyanophenyl)- (9CI)
4-Boronobenzonitrile
4-Boronobenzonitrile~4-Cyanophenylboronic acid
PARACYANOPHENYLBORONIC ACID
4-Cyanophenylboronic Acid (contains varying amounts of Anhydride)
4-Cyanophenylboronic acid ,98%
4-Cyanophenylboronic acid,97%
4-Cyanophenylboronic acid, 97%, May contain varying aMounts of anhydride
4-Cyanophenylboronic
4-Cyanophenylboronic acid , May contain varying amounts of anhydride, 97%
(4-cyanophenyl)boronic acid(SALTDATA: FREE)
-CYANOBENZENEBORONIC ACID
B-(4-Cyanophenyl)boronic acid
4-Cyanophenylboronic acid, 98%, for synthesis
4-Cyanophenylboronicaci
SWF-108
126747-14-6 4-Cyanophenylboronic acid
4-Cyanophenylboronic Acid extrapure, 95%
2-Cyanophenylboroic acid
13C6]-4-Cyanophenylboronic acid
4-cyanobboronic acid
126747-14-6
12647-14-6
Organometallic Reagents
BORONIC ACID
Boronic Acids and Derivatives
Aryl
B (Classes of Boron Compounds)
Boronic Acids
Boronic Acid
Aryl
Organoborons
Boronic Acids & Esters
Phenyls & Phenyl-Het
Boronic acids
B (Classes of Boron Compounds)
Boronic Acids & Esters
Phenyls & Phenyl-Het
Boronic Acids
Boronic Acids and Derivatives
Substituted Boronic Acids
NITRILE
blocks
BoronicAcids
Carboxes
Boronate Ester
Potassium Trifluoroborate
bc0001