ChemicalBook >> CAS DataBase List >>MI-136
MI-136
- CAS No.
- 1628316-74-4
- Chemical Name:
- MI-136
- Synonyms
- MI-136;CS-2162;MI136;MI 136;HY-19319 (MI 136;MI-136;HY-19319 (MI 136; MI136);;5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-in;5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile;1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-;PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen Receptor,Epigenetic Reader Domain,prostate
- CBNumber:
- CB83121119
- Molecular Formula:
- C23H21F3N6S
- Molecular Weight:
- 470.51
- MDL Number:
- MFCD28506294
- MOL File:
- 1628316-74-4.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:02:36
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| NFPA 704 |
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MI-136 price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19245 | MI-136 ≥98% | 1628316-74-4 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 19245 | MI-136 ≥98% | 1628316-74-4 | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 19245 | MI-136 ≥98% | 1628316-74-4 | 10mg | $283 | 2024-03-01 | Buy |
| Cayman Chemical | 19245 | MI-136 ≥98% | 1628316-74-4 | 25mg | $618 | 2024-03-01 | Buy |
| ChemScene | CS-5526 | MI-136 98.64% | 1628316-74-4 | 50mg | $650 | 2021-12-16 | Buy |
MI-136 Chemical Properties,Uses,Production
Description
MI-136 is an inhibitor of the menin-MLL interaction (IC50 = 31 nM; Kd = 23.6 nM). By blocking MLL recruitment predominantly at the level of the menin-MLL interaction, it can inhibit androgen receptor (AR)-mediated transcription. At 40 mg/kg, MI-136 has been shown to block AR signaling, inhibiting the growth of castration-resistant tumors in mice.
MI-136 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 65)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4664 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
1628316-74-4(MI-136)Related Search:
MI-136
MI-136;HY-19319 (MI 136; MI136);
HY-19319 (MI 136
1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-
5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile
5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-in
MI136;MI 136
CS-2162
PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen Receptor,Epigenetic Reader Domain,prostate
1628316-74-4
C23H21F3N6S