BAX INHIBITING PEPTIDE V5 (BIP-V5)
- CAS No.
- 579492-81-2
- Chemical Name:
- BAX INHIBITING PEPTIDE V5 (BIP-V5)
- Synonyms
- Val-Pro-Met-Leu-Lys;VAL-PRO-MET-LEU-LYS;BIP-V5;Bax inhibitor peptide V5 TFA;BAX INHIBITOR PEPTIDE V5, >99%;Bax inhibitor peptide V5 (BIP-V5);BAX INHIBITING PEPTIDE V5 (BIP-V5);L-Lysine, L-valyl-L-prolyl-L-methionyl-L-leucyl-;VAL-PRO-MET-LEU-LYS;BIP-V5;BAX INHIBITING PEPTIDE V5;BAX Inhibiting Peptide V5 >=97% (HPLC), lyophilized powder;Bax inhibitor peptide V5，Val-Pro-Met-Leu-Lys， BIP-V5，BAX Inhibiting Peptide V5
- CBNumber:
- CB8503178
- Molecular Formula:
- C27H50N6O6S
- Molecular Weight:
- 586.79
- MDL Number:
- MFCD11045561
- MOL File:
- 579492-81-2.mol
- MSDS File:
- SDS
BAX INHIBITING PEPTIDE V5 (BIP-V5) price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B1436 | BAX Inhibiting Peptide V5 ≥97% (HPLC), lyophilized powder | 579492-81-2 | 5mg | $188 | 2024-03-01 | Buy |
| Cayman Chemical | 30243 | Bax Inhibitor Peptide V5 | 579492-81-2 | 1mg | $36 | 2024-03-01 | Buy |
| Cayman Chemical | 30243 | Bax Inhibitor Peptide V5 | 579492-81-2 | 10mg | $308 | 2024-03-01 | Buy |
| Cayman Chemical | 30243 | Bax Inhibitor Peptide V5 | 579492-81-2 | 5mg | $163 | 2024-03-01 | Buy |
| TRC | B129293 | BaxInhibitorPeptideV5 | 579492-81-2 | 10mg | $495 | 2021-12-16 | Buy |
BAX INHIBITING PEPTIDE V5 (BIP-V5) Chemical Properties,Uses,Production
Description
Bax inhibitor peptide V5 is an inhibitor of Bax. It decreases levels of the pro-apoptotic proteins Bax, Bad, and NF-ĸB p65 and increases levels of the anti-apoptotic proteins X-linked inhibitor of apoptosis (XIAP) and Bcl-2 in isolated mouse pancreatic islets when used at a concentration of 100 μM. It inhibits apoptosis induced by etoposide in Hep3B human hepatoma cells when used at a concentration of 200 μM. Bax inhibitor peptide V5 (5 mg/ml, i.c.v.) decreases infarct volume and reduces ipsilateral paw preference in the cylinder rearing test, indicating an improvement in sensorimotor function, in a neonatal mouse model of hypoxic-ischemia brain injury induced by carotid artery ligation. Bax inhibitor peptide V5, when used at a concentration of 100 μM in syngeneic pancreatic islet cells prior to transplantation, inhibits increases in blood glucose levels in an intraperitoneal glucose tolerance test and increases survival in a mouse model of diabetes induced by streptozotocin (STZ; ).
Biochem/physiol Actions
BAX Inhibiting Peptide V5 protects Bax against conformational changes and it also prevents mitochondrial translocation. In vitro analysis prove that peptide V5 prevents apoptosis, mediated by a number of agents including staurosporine, ultraviolet and anti-cancer drug.
References
[1]. sawada m, hayes p, matsuyama s. cytoprotective membrane-permeable peptides designed from the bax-binding domain of ku70. nat cell biol, 2003, 5(4): 352-357.
[2]. rivas-carrillo jd, soto-gutierrez a, navarro-alvarez n, et al. cell-permeable pentapeptide v5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice. diabetes, 2007, 56(5): 1259-1267.
BAX INHIBITING PEPTIDE V5 (BIP-V5) Preparation Products And Raw materials
Raw materials
Preparation Products
BAX INHIBITING PEPTIDE V5 (BIP-V5) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10247 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3582 | 58 |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
View Lastest Price from BAX INHIBITING PEPTIDE V5 (BIP-V5) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-02-19 | BAX INHIBITING PEPTIDE V5 (BIP-V5)
579492-81-2
|
US $7.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
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- BAX INHIBITING PEPTIDE V5 (BIP-V5)
579492-81-2
- US $7.00 / KG
- 99%
- Career Henan Chemical Co