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Emedastine

CAS No.
87233-61-2
Chemical Name:
Emedastine
Synonyms
EMEDASTINE;Emedastine impurity F;Emedastine Impurity 14;1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole;1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole;1-(2-ethoxyethyl)-2-(4-Methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole;1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole;1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepine-1-yl)-1H-benzimidazole;1-(2-Ethoxyethyl)-2-[(hexahydro-4-methyl-1H-1,4-diazepin)-1-yl]-1H-benzimidazole;allergic,Histamine Receptor,antiallergic,benzimidazole,Inhibitor,skin,inhibit,Emedastine,orally,rhinitis,diseases,conjunctivitis
CBNumber:
CB8728076
Molecular Formula:
C17H26N4O
Molecular Weight:
302.41
MDL Number:
MFCD00865647
MOL File:
87233-61-2.mol
MSDS File:
SDS
Last updated:2023-09-04 15:51:00

Emedastine Properties

Boiling point 446.6±55.0 °C(Predicted)
Density 1.15±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 125 mg/mL (413.35 mM); Ethanol: 100 mg/mL (330.68 mM)
pka 8.86±0.10(Predicted)
CAS DataBase Reference 87233-61-2(CAS DataBase Reference)
FDA UNII 9J1H7Y9OJV
ATC code S01GX06

Emedastine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0028590 Emedastine ≥98.0% 87233-61-2 5mg $350 2021-12-16 Buy
American Custom Chemicals Corporation API0009136 EMEDASTINE 95.00% 87233-61-2 5MG $496.67 2021-12-16 Buy
ChemScene CS-0028590 Emedastine ≥98.0% 87233-61-2 10mg $550 2021-12-16 Buy
ChemScene CS-0028590 Emedastine ≥98.0% 87233-61-2 50mg $1650 2021-12-16 Buy
ChemScene CS-0028590 Emedastine ≥98.0% 87233-61-2 100mg $2250 2021-12-16 Buy
Product number Packaging Price Buy
CS-0028590 5mg $350 Buy
API0009136 5MG $496.67 Buy
CS-0028590 10mg $550 Buy
CS-0028590 50mg $1650 Buy
CS-0028590 100mg $2250 Buy

Emedastine Chemical Properties,Uses,Production

Uses

Antihistaminic, H1-receptor; asthma prophylactic; anti-allergic.

Definition

ChEBI: 1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the ifumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.

brand name

Emadine (Alcon).

Clinical Use

Emedastine also is a newer antihistamine used topically in the eye for conjunctivitis. It has very high H1 receptor selectivity characteristics, and it is structurally related to the benzimidazoles, such as astemizole. Inhibition of mast cell release of inflammatory mediators has been noted.

4857-06-1
87233-61-2
Synthesis of Emedastine from 2-Chlorobenzimidazole
Global( 83)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9341 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49391 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9923 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58

View Lastest Price from Emedastine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Emedastine pictures 2020-01-15 Emedastine
87233-61-2
US $1.00 / g 1g 95-99% 1ton Career Henan Chemical Co
  • Emedastine pictures
  • Emedastine
    87233-61-2
  • US $1.00 / g
  • 95-99%
  • Career Henan Chemical Co

Emedastine Spectrum

EMEDASTINE 1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole 1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepine-1-yl)-1H-benzimidazole 1-(2-Ethoxyethyl)-2-[(hexahydro-4-methyl-1H-1,4-diazepin)-1-yl]-1H-benzimidazole 1-(2-ethoxyethyl)-2-(4-Methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole 1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole Emedastine impurity F allergic,Histamine Receptor,antiallergic,benzimidazole,Inhibitor,skin,inhibit,Emedastine,orally,rhinitis,diseases,conjunctivitis Emedastine Impurity 14 87233-61-2 C17H26N4O impurity DCP