ChemicalBook >> CAS DataBase List >>4-Chloro-2,6-diaminopyrimidine

4-Chloro-2,6-diaminopyrimidine

CAS No.
156-83-2
Chemical Name:
4-Chloro-2,6-diaminopyrimidine
Synonyms
2,4-DIAMINO-6-CHLOROPYRIMIDINE;6-CHLORO-PYRIMIDINE-2,4-DIAMINE;NSC 8818;JACS-156-83-2;TIMTEC-BB SBB004123;4-Chloro-2,6-diamino;DiaMino-6-chloropyriMid;Minoxidil EP Impurity B;Minoxidil EP Impurity 3;oro-2,6-diaminopyrimidine
CBNumber:
CB9194300
Molecular Formula:
C4H5ClN4
Molecular Weight:
144.56
MDL Number:
MFCD00006097
MOL File:
156-83-2.mol
MSDS File:
SDS
Last updated:2024-09-29 20:12:18

4-Chloro-2,6-diaminopyrimidine Properties

Melting point 199-202 °C(lit.)
Boiling point 199-202 °C
Density 1.3966 (rough estimate)
vapor pressure 0.0±1.1 mmHg at 25°C
refractive index 1.702
Flash point 218.9±29.6 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility slightly soluble
pka 3.66±0.10(Predicted)
form Solid
color White to Pale Yellow
Water Solubility slightly soluble
BRN 118455
InChI InChI=1S/C4H5ClN4/c5-2-1-3(6)9-4(7)8-2/h1H,(H4,6,7,8,9)
InChIKey QJIUMVUZDYPQRT-UHFFFAOYSA-N
SMILES C1(N)=NC(Cl)=CC(N)=N1
CAS DataBase Reference 156-83-2(CAS DataBase Reference)
FDA UNII 83NU5F7ZAS
NIST Chemistry Reference Pyrimidine, 6-chloro-2,4-diamino-(156-83-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-24/25
WGK Germany  3
Hazard Note  Irritant
HS Code  29335995
NFPA 704
1
2 0

4-Chloro-2,6-diaminopyrimidine price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C33204 2,6-Diamino-4-chloropyrimidine 98% 156-83-2 5g $53.3 2024-03-01 Buy
Sigma-Aldrich C33204 2,6-Diamino-4-chloropyrimidine 98% 156-83-2 25g $166 2024-03-01 Buy
TCI Chemical C0811 6-Chloro-2,4-diaminopyrimidine >98.0%(GC)(T) 156-83-2 25g $58 2024-03-01 Buy
Alfa Aesar A17780 2,4-Diamino-6-chloropyrimidine, 98% 156-83-2 25g $0 2021-12-16 Buy
Alfa Aesar A17780 2,4-Diamino-6-chloropyrimidine, 98% 156-83-2 5g $38.8 2021-12-16 Buy
Product number Packaging Price Buy
C33204 5g $53.3 Buy
C33204 25g $166 Buy
C0811 25g $58 Buy
A17780 25g $0 Buy
A17780 5g $38.8 Buy

4-Chloro-2,6-diaminopyrimidine Chemical Properties,Uses,Production

Chemical Properties

White Cyrstalline Solid

Uses

Melamine and Related Compounds in Dog Food Using GC-MS

Definition

ChEBI: 6-chloro-2,4-pyrimidinediamine (4-Chloro-2,6-diaminopyrimidine) is a member of pyrimidines and an organohalogen compound.

Synthesis

2,4-Diamino-6-hydroxypyrimidine (1.00 g, 7.93 mmol) was added to POCl3 (9 mL) and stirred at 97 ℃ for 17 h. The reaction solution was added to ice water slowly and then stirred at 90 C for 1 h. The pH of this solution was adjusted to 8 with NaOH, and then it was extracted with EtOAC (150 mL 3). The combined organic layers were dried with Na2SO4, filtered, and concentrated to give white solid 4-Chloro-2,6-diaminopyrimidine 0.97 g, yielding 85%.
4-Chloro-2,6-diaminopyrimidine

Purification Methods

It recrystallises from boiling H2O (charcoal) as needles; it also crystallises from Me2CO. [Büttner Chem Ber 36 2232 1903, Roth J Am Chem Soc 72 1914 1950, UV: Brown & Jacobsen J Chem Soc 3172 1962, Beilstein 24 H 318, 25 III/IV 2788.]

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View Lastest Price from 4-Chloro-2,6-diaminopyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Chloro-2,6-diaminopyrimidine pictures 2024-10-31 4-Chloro-2,6-diaminopyrimidine
156-83-2
US $20.00 / kg 1kg 99% 2000kg hebei hongtan Biotechnology Co., Ltd
4-Chloro-2,6-diaminopyrimidine pictures 2024-10-31 4-Chloro-2,6-diaminopyrimidine
156-83-2
US $5.00 / kg 1kg ≥99% 1000mt/year Jinan Finer Chemical Co., Ltd
4-Chloro-2,6-diaminopyrimidine pictures 2024-10-11 4-Chloro-2,6-diaminopyrimidine
156-83-2
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
4-DiaMino-6-chloropyriMidine NSC 8818 DIAMINO-6-CHLOROPYRIMIDINE, 2,4-(SH) 2,4-DIAMINO-6-CHLOROPYRIMIDINE FOR SYNTH 2,6-DiaMino-4-chloropyriMidine 98% DiaMino-6-chloropyriMid 2,4-Diamino-6-chloropyrimidine,98% 4-Chloro-2,6-diaminopyrimidine, 4-Chloro-2,6-diamino-1,3-diazine 2,4-Diamino-6-chloropyrimidine for synthesis 2-AMINO-6-CHLORO-4-PYRIMIDINYLAMINE Pyrimidine,2,4-diamino-6-chloro- 2,4-Diamino-6-Chloro Pyridine 2,6-DIAMINO-4-CHLORO PYRIMIDINE 4-Chloro-2-6-Diaminopyrimide 2,4-Diamino-6-chloropyrimidine, 99+% 2,4-Pyrimidinediamine, 6-chloro- (9CI) 6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine 2,4-DIAMINO-6-CHLOROPYRIMIDINE/ MINOXIDIL 4-CHLORO-2,6-DIAMINOPYRIMIDINE 98% 4-CHLORO-2,6-DIAMINOPYRIMIDINE (2,4-DIAMINO-6-CHLOROPYRIMIDINE) 4-Chloropyrimidine-2,6-diamine 4-Chloro-2,6-diaminopyrimidine,98% 4-Chloro-2,6-diaminopyrimidine ,99% 2,6-Diamino-4-chloropyrimidine,4-Chloro-2,6-diaminopyrimidine 4-Chloro-2,6-diamino 2,6-Diamino-4-chloropyrimidine ,98% 2,6-Diamino-4-chloropyrimidine (Internal Standard) 4-CHLORO-2,6-DIAMINOPYRIMIDINE 6-CHLORO-PYRIMIDINE-2,4-DIYLDIAMINE 6-CHLORO-2,4-DIAMINOPYRIMIDINE TIMTEC-BB SBB004123 2,4-Pyrimidinediamine, 6-chloro- 2,4-Pyrimidinediamine,6-chloro- 4-Chloro-2,6-pyrimidinediamine 6-Chlor-2,4-diaminopyrimidin(4-2,6) 6-Chloro-2,4-pyrimidinediamine 6-chloro-4-pyrimidinediamine 156-83-2, MFCD00006097, 4-Chloro-2,6-diaminopyrimidine JACS-156-83-2 Minoxidil EP Impurity B 2,6-Diamini-4-chloro pyrimidine 2,4-Diamino-6-chloropyramidine Minoxidil Impurity 2(Minoxidil EP Impurity B) 6-Chloro-2,4-diaminopyrimidine > 2,6-Diamino-4-chloropyrimidine (Internal Standard)@1000 μg/mL in Pyridine 156-83-2, MFCD00006097, 4-ChL oro-2,6-diaminopyrimidine 2,4-DIAMINO-6-CHLOROPYRIMIDINE 6-CHLORO-PYRIMIDINE-2,4-DIAMINE 2,4-Diamino-6-chloropyrimidine (2,4-DACP) Minoxidil EP Impurity 3 DIAMINO-6-CHLOROPYRIMIDINE, 2,4- C12193500 2,6-Diamino-4-chloropyrimidine 156-83-2 C4H5CIN4 HETERO CHLORIDE Pyrimidines Heterocyclic Building Blocks